Gladyshev, Vadim N.

Comparative Genomics of Trace Elements: Emerging Dynamic View of Trace Element Utilization and Function

Zhang, Y., & Gladyshev, V. N. (2009) · Chemical Reviews

Trace Elements in HealthPlant Micronutrient Interactions and Effects

Cited by 143

Chemically induced reprogramming to reverse cellular aging

Yang, J.-H., Petty, C. A., Dixon-McDougall, T., Lopez, M. V., Tyshkovskiy, A., Maybury-Lewis, S., Tian, X., Ibrahim, N., Chen, Z., Griffin, P. T., et al. (2023) · Aging

Epigenetics and DNA MethylationTelomeres, Telomerase, and Senescence

Cited by 136

Pyrrolysine and Selenocysteine Use Dissimilar Decoding Strategies

Zhang, Y., Baranov, P. V., Atkins, J. F., & Gladyshev, V. N. (2005) · Journal of Biological Chemistry

RNA and protein synthesis mechanismsSelenium in Biological Systems

Cited by 135

Multi-omic rejuvenation and lifespan extension on exposure to youthful circulation

Zhang, B., Lee, D. E., Trapp, A., Tyshkovskiy, A., Lu, A. T., Bareja, A., Kerepesi, C., McKay, L. K., Shindyapina, A. V., Dmitriev, S. E., et al. (2023) · Nature Aging

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 134

Selective Inhibition of Selenocysteine tRNA Maturation and Selenoprotein Synthesis in Transgenic Mice Expressing Isopentenyladenosine-Deficient Selenocysteine tRNA

Moustafa, M. E., Carlson, B. A., El-Saadani, M. A., Kryukov, G. V., Sun, Q.-A., Harney, J. W., Hill, K. E., Combs, G. F., Feigenbaum, L., Mansur, D. B., et al. (2001) · Molecular and Cellular Biology

Selenium in Biological SystemsRNA and protein synthesis mechanisms

Cited by 131

Site-Specific Proteomic Mapping Identifies Selectively Modified Regulatory Cysteine Residues in Functionally Distinct Protein Networks

Gould, N. S., Evans, P., Martínez-Acedo, P., Marino, S. M., Gladyshev, V. N., Carroll, K. S., & Ischiropoulos, H. (2015) · Chemistry & Biology

Redox biology and oxidative stressAdvanced Proteomics Techniques and Applications

Cited by 128

DNA methylation networks underlying mammalian traits

Haghani, A., Li, C. Z., Robeck, T. R., Zhang, J., Lu, A. T., Ablaeva, J., Acosta-Rodríguez, V. A., Adams, D. M., Alagaili, A. N., Almunia, J., et al. (2023) · Science

Epigenetics and DNA MethylationGenetic Syndromes and Imprinting

Cited by 128

Selenoproteins Are Essential for Proper Keratinocyte Function and Skin Development

Sengupta, A., Lichti, U. F., Carlson, B. A., Ryscavage, A. O., Gladyshev, V. N., Yuspa, S. H., & Hatfield, D. L. (2010) · PLoS ONE

Selenium in Biological SystemsOrganoselenium and organotellurium chemistry

Cited by 109

Cell culture-based profiling across mammals reveals DNA repair and metabolism as determinants of species longevity

Ma, S., Upneja, A., Galecki, A., Tsai, Y.-M., Burant, C. F., Raskind, S., Zhang, Q., Zhang, Z. D., Seluanov, A., Gorbunova, V., et al. (2016) · eLife

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 89

Senolytic therapy alleviates physiological human brain aging and COVID-19 neuropathology

Aguado, J., Amarilla, A. A., Taherian Fard, A., Albornoz, E. A., Tyshkovskiy, A., Schwabenland, M., Chaggar, H. K., Modhiran, N., Gómez-Inclán, C., Javed, I., et al. (2023) · Nature Aging

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 80

Senolytic therapy alleviates physiological human brain aging and COVID-19 neuropathology

Aguado, J., Amarilla, A. A., Taherian Fard, A., Albornoz, E. A., Tyshkovskiy, A., Schwabenland, M., Chaggar, H. K., Modhiran, N., Gómez-Inclán, C., Javed, I., et al. (2023) · Nature Aging

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 80

Senolytic therapy alleviates physiological human brain aging and COVID-19 neuropathology

Aguado, J., Amarilla, A., Fard, A. T., Albornoz, E., Tyshkovskiy, A., Schwabenland, M., Chaggar, H., Modhiran, N., Gómez-Inclán, C., Javed, I., et al. (2023) · Nature Aging

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 80

Knocking out multigene redundancies via cycles of sexual assortment and fluorescence selection

Suzuki, Y., Onge, R. P. S., Mani, R., King, O. D., Heilbut, A., Labunskyy, V. M., Chen, W., Pham, L., Zhang, L. V., Tong, A. H. Y., et al. (2011) · Nature Methods

Fungal and yeast genetics researchDrug Transport and Resistance Mechanisms

Cited by 78

Dual functions of codons in the genetic code

Lobanov, A. V., Turanov, A. A., Hatfield, D. L., & Gladyshev, V. N. (2010) · Critical Reviews in Biochemistry and Molecular Biology

RNA and protein synthesis mechanismsOrigins and Evolution of Life

Cited by 64

Evidence that mutation accumulation does not cause aging in Saccharomyces cerevisiae

Kaya, A., Lobanov, A. V., & Gladyshev, V. N. (2015) · Aging Cell

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 60

Recharging oxidative protein repair: Catalysis by methionine sulfoxide reductases towards their amino acid, protein, and model substrates

Tarrago, L., & Gladyshev, V. N. (2012) · Biochemistry (Moscow)

Redox biology and oxidative stressSulfur Compounds in Biology

Cited by 43

The selenoprotein methionine sulfoxide reductase B1 (MSRB1)

Tarrago, L., Kaya, A., Kim, H.-Y., Manta, B., Lee, B.-C., & Gladyshev, V. N. (2022) · Free Radical Biology and Medicine

Selenium in Biological SystemsRedox biology and oxidative stress

Cited by 39

Erosion of the Epigenetic Landscape and Loss of Cellular Identity as a Cause of Aging in Mammals

Yang, J.-H., Griffin, P. T., Vera, D. L., Apostolides, J. K., Hayano, M., Meer, M. V., Salfati, E. L., Su, Q., Munding, E. M., Blanchette, M., et al. (2019) · bioRxiv (Cold Spring Harbor Laboratory)

Epigenetics and DNA MethylationGenetics, Aging, and Longevity in Model Organisms

Cited by 38

Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation

Mitchell, W., Goeminne, L. J., Tyshkovskiy, A., Zhang, S., Chen, J. Y., Paulo, J. A., Pierce, K. A., Choy, A. H., Clish, C. B., Gygi, S. P., et al. (2024) · eLife

Pluripotent Stem Cells ResearchTelomeres, Telomerase, and Senescence

Cited by 33

A review of the biomedical innovations for healthy longevity

Moskalev, A., Anisimov, V., Aliper, A., Artemov, A., Asadullah, K., Belsky, D., Baranova, A., de Grey, A., Dixit, V. D., Debonneuil, E., et al. (2017) · Aging

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 22

Selenium utilization in thioredoxin and catalytic advantage provided by selenocysteine

Kim, M.-J., Lee, B. C., Hwang, K. Y., Gladyshev, V. N., & Kim, H.-Y. (2015) · Biochemical and Biophysical Research Communications

Selenium in Biological SystemsRedox biology and oxidative stress

Cited by 22

Reversal of ageing- and injury-induced vision loss by Tet-dependent epigenetic reprogramming

Lu, Y., Krishnan, A., Brommer, B., Tian, X., Meer, M., Vera, D. L., Wang, C., Zeng, Q., Yu, D., Bonkowski, M. S., et al. (2019) · bioRxiv (Cold Spring Harbor Laboratory)

Epigenetics and DNA MethylationRetinal Development and Disorders

Cited by 20

Longevity and rejuvenation effects of cell reprogramming are decoupled from loss of somatic identity.

Kriukov, D., Khrameeva, E. E., Gladyshev, V. N., Dmitriev, S. E., & Tyshkovskiy, A. (2022) · bioRxiv (Cold Spring Harbor Laboratory)

Pluripotent Stem Cells ResearchGenetics, Aging, and Longevity in Model Organisms

Cited by 13

Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation

Mitchell, W., Goeminne, L. J. E., Tyshkovskiy, A., Zhang, S., Chen, J. Y., Paulo, J. A., Pierce, K. A., Choy, A. H., Clish, C. B., Gygi, S. P., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory)

Pluripotent Stem Cells ResearchTelomeres, Telomerase, and Senescence

Cited by 2