Wilson, Ian A.

Glycosylation and the Immune System

Rudd, P. M., Elliott, T., Cresswell, P., Wilson, I. A., & Dwek, R. A. (2001) · Science

Glycosylation and Glycoproteins ResearchCarbohydrate Chemistry and Synthesis

Cited by 1,588

Broad neutralization coverage of HIV by multiple highly potent antibodies

Walker, L. M., Huber, M., Doores, K. J., Falkowska, E., Pejchal, R., Julien, J.-P., Wang, S.-K., Ramos, A., Chan-Hui, P.-Y., Moyle, M., et al. (2011) · Nature

HIV Research and TreatmentMonoclonal and Polyclonal Antibodies Research

Cited by 1,480

Antibody Recognition of a Highly Conserved Influenza Virus Epitope

Ekiert, D. C., Bhabha, G., Elsliger, M.-A., Friesen, R. H. E., Jongeneelen, M., Throsby, M., Goudsmit, J., & Wilson, I. A. (2009) · Science

Influenza Virus Research Studiesvaccines and immunoinformatics approaches

Cited by 1,326

Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model

Rogers, T. F., Zhao, F., Huang, D., Beutler, N., Burns, A., He, W.-T., Limbo, O., Smith, C., Song, G., Woehl, J., et al. (2020) · Science

SARS-CoV-2 and COVID-19 ResearchAnimal Virus Infections Studies

Cited by 1,230

Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

McLellan, J. S., Pancera, M., Carrico, C., Gorman, J., Julien, J.-P., Khayat, R., Louder, R., Pejchal, R., Sastry, M., Dai, K., et al. (2011) · Nature

HIV Research and TreatmentCarbohydrate Chemistry and Synthesis

Cited by 830

Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors

Jardine, J., Julien, J.-P., Menis, S., Ota, T., Kalyuzhniy, O., McGuire, A., Sok, D., Huang, P.-S., MacPherson, S., Jones, M., et al. (2013) · Science

HIV Research and TreatmentSARS-CoV-2 and COVID-19 Research

Cited by 770

Changes in the conformation of influenza virus hemagglutinin at the pH optimum of virus-mediated membrane fusion

Skehel, J. J., Bayley, P. M., Brown, E. B., Martin, S. R., Waterfield, M. D., White, J. M., Wilson, I. A., & Wiley, D. C. (1982) · Proceedings of the National Academy of Sciences

Influenza Virus Research StudiesCellular transport and secretion

Cited by 726

A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield

Pejchal, R., Doores, K. J., Walker, L. M., Khayat, R., Huang, P.-S., Wang, S.-K., Stanfield, R. L., Julien, J.-P., Ramos, A., Crispin, M., et al. (2011) · Science

HIV Research and TreatmentMonoclonal and Polyclonal Antibodies Research

Cited by 694

Glycan Microarray Analysis of the Hemagglutinins from Modern and Pandemic Influenza Viruses Reveals Different Receptor Specificities

Stevens, J., Blixt, O., Glaser, L., Taubenberger, J. K., Palese, P., Paulson, J. C., & Wilson, I. A. (2006) · Journal of Molecular Biology

Influenza Virus Research StudiesGlycosylation and Glycoproteins Research

Cited by 613

Structural basis of a shared antibody response to SARS-CoV-2

Yuan, M., Liu, H., Wu, N. C., Lee, C.-C. D., Zhu, X., Zhao, F., Huang, D., Yu, W., Hua, Y., Tien, H., et al. (2020) · Science

SARS-CoV-2 and COVID-19 Researchvaccines and immunoinformatics approaches

Cited by 589

Computational Design of Proteins Targeting the Conserved Stem Region of Influenza Hemagglutinin

Fleishman, S. J., Whitehead, T. A., Ekiert, D. C., Dreyfus, C., Corn, J. E., Strauch, E.-M., Wilson, I. A., & Baker, D. (2011) · Science

Protein Structure and DynamicsInfluenza Virus Research Studies

Cited by 585

Design of protein-binding proteins from the target structure alone

Cao, L., Coventry, B., Goreshnik, I., Huang, B., Sheffler, W., Park, J. S., Jude, K. M., Marković, I., Kadam, R. U., Verschueren, K. H. G., et al. (2022) · Nature

Protein Structure and DynamicsChemical Synthesis and Analysis

Cited by 577

Massively parallel de novo protein design for targeted therapeutics

Chevalier, A., Silva, D.-A., Rocklin, G. J., Hicks, D. R., Vergara, R., Murapa, P., Bernard, S. M., Zhang, L., Lam, K.-H., Yao, G., et al. (2017) · Nature

Protein Structure and DynamicsMonoclonal and Polyclonal Antibodies Research

Cited by 453

Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants

Yuan, M., Huang, D., Lee, C.-C. D., Wu, N. C., Jackson, A. M., Zhu, X., Liu, H., Peng, L., van Gils, M. J., Sanders, R. W., et al. (2021) · Science

SARS-CoV-2 and COVID-19 Researchvaccines and immunoinformatics approaches

Cited by 364

A Therapeutic Non-self-reactive SARS-CoV-2 Antibody Protects from Lung Pathology in a COVID-19 Hamster Model

Kreye, J., Reincke, S. M., Kornau, H.-C., Sánchez-Sendin, E., Corman, V. M., Liu, H., Yuan, M., Wu, N. C., Zhu, X., Lee, C.-C. D., et al. (2020) · Cell

SARS-CoV-2 and COVID-19 ResearchMonoclonal and Polyclonal Antibodies Research

Cited by 347

Structural Evolution of Glycan Recognition by a Family of Potent HIV Antibodies

Garces, F., Sok, D., Kong, L., McBride, R., Kim, H. J., Saye-Francisco, K. F., Julien, J.-P., Hua, Y., Cupo, A., Moore, J. P., et al. (2014) · Cell

HIV Research and TreatmentMonoclonal and Polyclonal Antibodies Research

Cited by 178

Potent peptidic fusion inhibitors of influenza virus

Kadam, R. U., Juraszek, J., Brandenburg, B., Buyck, C., Schepens, W. B. G., Kesteleyn, B., Stoops, B., Vreeken, R. J., Vermond, J., Goutier, W., et al. (2017) · Science

Influenza Virus Research Studiesvaccines and immunoinformatics approaches

Cited by 165

Genetically encoding phosphotyrosine and its nonhydrolyzable analog in bacteria

Luo, X., Fu, G., Wang, R. E., Zhu, X., Zambaldo, C., Liu, R., Liu, T., Lyu, X., Du, J., Xuan, W., et al. (2017) · Nature Chemical Biology

RNA and protein synthesis mechanismsBacterial Genetics and Biotechnology

Cited by 134

Molecular basis for recognition of methylated and specific DNA sequences by the zinc finger protein Kaiso

Buck-Koehntop, B. A., Stanfield, R. L., Ekiert, D. C., Martinez-Yamout, M. A., Dyson, H. J., Wilson, I. A., & Wright, P. E. (2012) · Proceedings of the National Academy of Sciences

Epigenetics and DNA MethylationProtein Structure and Dynamics

Cited by 128

Computational design of trimeric influenza-neutralizing proteins targeting the hemagglutinin receptor binding site

Strauch, E.-M., Bernard, S. M., La, D., Bohn, A. J., Lee, P. S., Anderson, C. E., Nieusma, T., Holstein, C. A., Garcia, N. K., Hooper, K. A., et al. (2017) · Nature Biotechnology

Influenza Virus Research StudiesProtein Structure and Dynamics

Cited by 119

Detailed Analysis of the Free and Bound Conformations of an Antibody

Schulze-Gahmen, U., Rini, J. M., & Wilson, I. A. (1993) · Journal of Molecular Biology

Enzyme Structure and FunctionMonoclonal and Polyclonal Antibodies Research

Cited by 96

Chemoselective small molecules that covalently modify one lysine in a non-enzyme protein in plasma

Choi, S., Connelly, S., Reixach, N., Wilson, I. A., & Kelly, J. W. (2010) · Nature Chemical Biology

Amyloidosis: Diagnosis, Treatment, OutcomesAlzheimer's disease research and treatments

Cited by 90

Sequence signatures of two public antibody clonotypes that bind SARS-CoV-2 receptor binding domain

Tan, T. J. C., Yuan, M., Kuzelka, K., Padron, G. C., Beal, J. R., Chen, X., Wang, Y., Rivera-Cardona, J., Zhu, X., Stadtmueller, B. M., et al. (2021) · Nature Communications

SARS-CoV-2 and COVID-19 ResearchMonoclonal and Polyclonal Antibodies Research

Cited by 75

Triple tandem trimer immunogens for HIV-1 and influenza nucleic acid-based vaccines

del Moral-Sánchez, I., Wee, E. G., Xian, Y., Lee, W.-H., Allen, J. D., Torrents de la Peña, A., Rocha, R. F., Ferguson, J., León, A. N., Koekkoek, S., et al. (2023) · npj Vaccines

HIV Research and TreatmentSARS-CoV-2 and COVID-19 Research

Cited by 14