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Inhibition of Viral Membrane Fusion by Peptides and Approaches to Peptide Design

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A targeted boost-and-sort immunization strategy using Escherichia coli BamA identifies rare growth inhibitory antibodies

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Non-competitive cyclic peptides for targeting enzyme–substrate complexes

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Chemoreactive-Inspired Discovery of Influenza A Virus Dual Inhibitor to Block Hemagglutinin-Mediated Adsorption and Membrane Fusion

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Discovery of Highly Potent Pinanamine-Based Inhibitors against Amantadine- and Oseltamivir-Resistant Influenza A Viruses

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Downsizing antibodies: Towards complementarity-determining region (CDR)-based peptide mimetics

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A small-molecule fragment that emulates binding of receptor and broadly neutralizing antibodies to influenza A hemagglutinin

Kadam, R. U., & Wilson, I. A. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1801999115 · Cited by 33 · see citing works

Leveraging the therapeutic, biological, and self-assembling potential of peptides for the treatment of viral infections

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Effective in Vivo Targeting of Influenza Virus through a Cell-Penetrating/Fusion Inhibitor Tandem Peptide Anchored to the Plasma Membrane

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A Review: The Antiviral Activity of Cyclic Peptides

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Quinones as Promising Compounds against Respiratory Viruses: A Review

Chan‐Zapata, I., Borges-Argáez, R., & Ayora‐Talavera, G. (2023) · Molecules · doi:10.3390/molecules28041981 · Cited by 30 · see citing works

Emerging and state of the art hemagglutinin-targeted influenza virus inhibitors.

Zhang, Q., Liang, T., Nandakumar, K. S., & Liu, S. (2020) · Expert Opinion on Pharmacotherapy · doi:10.1080/14656566.2020.1856814 · Cited by 29 · see citing works

Structural Classification of CDR-H3 in Single-Domain VHH Antibodies

Kuroda, D., & Tsumoto, K. (2022) · Methods in molecular biology · doi:10.1007/978-1-0716-2609-2_2 · Cited by 27 · see citing works

Antiviral peptides against Enterovirus A71 causing hand, foot and mouth disease

Lalani, S., Gew, L. T., & Poh, C. L. (2020) · Peptides · doi:10.1016/j.peptides.2020.170443 · Cited by 27 · see citing works

Translation of Mycobacterium Survival Strategy to Develop a Lipo‐peptide based Fusion Inhibitor**

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Antiviral Peptides as Anti-Influenza Agents

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Novel Small Molecule Targeting the Hemagglutinin Stalk of Influenza Viruses

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Development of Peptide Paratope Mimics Derived from the Anti-ROR1 Antibody and Long-Acting Peptide–Drug Conjugates for Targeted Cancer Therapy

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Fusion-inhibition peptide broadly inhibits influenza virus and SARS-CoV-2, including Delta and Omicron variants

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Stabilisation of Viral Membrane Fusion Proteins in Prefusion Conformation by Structure-Based Design for Structure Determination and Vaccine Development

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Structural basis for a human broadly neutralizing influenza A hemagglutinin stem-specific antibody including H17/18 subtypes

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A mini-review and perspective on multicyclic peptide mimics of antibodies

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Computationally Designed Cyclic Peptides Derived from an Antibody Loop Increase Breadth of Binding for Influenza Variants

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N-benzyl 4,4-disubstituted piperidines as a potent class of influenza H1N1 virus inhibitors showing a novel mechanism of hemagglutinin fusion peptide interaction

de Castro, S., Ginex, T., Vanderlinden, E., Laporte, M., Stevaert, A., Cumella, J., Gago, F., Camarasa, M., Luque, F. J., Naesens, L. M. J., et al. (2020) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2020.112223 · Cited by 24 · see citing works

Unique binding pattern for a lineage of human antibodies with broad reactivity against influenza A virus

Sun, X., Liu, C., Lü, X., Ling, Z., Yi, C., Zhang, Z., Li, Z., Jin, M., Wang, W., Tang, S., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-29950-w · Cited by 22 · see citing works

Targeting an evolutionarily conserved “E-L-L” motif in spike protein to identify a small molecule fusion inhibitor against SARS-CoV-2

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Selective thiazoline peptide cyclisation compatible with mRNA display and efficient synthesis

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The inducible amphisome isolates viral hemagglutinin and defends against influenza A virus infection

Omi, J., Watanabe‐Takahashi, M., Igai, K., Shimizu, E., Tseng, C.-Y., Miyasaka, T., Waku, T., Hama, S., Nakanishi, R., Goto, Y., et al. (2020) · Nature Communications · doi:10.1038/s41467-019-13974-w · Cited by 21 · see citing works

Prediction of the binding interface between monoclonal antibody m102.4 and Nipah attachment glycoprotein using structure-guided alanine scanning and computational docking

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Unique structural solution from a VH3-30 antibody targeting the hemagglutinin stem of influenza A viruses

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Crystal structure of the A/Viet Nam/1203/2004(H5N1) influenza virus hemagglutinin in complex with small molecule N-Cyclohexyltaurine

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Structural proteomics, electron cryo-microscopy and structural modeling approaches in bacteria–human protein interactions

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Molecular Complementarity of Proteomimetic Materials for Target‐Specific Recognition and Recognition‐Mediated Complex Functions

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Outlining recent updates on influenza therapeutics and vaccines: A comprehensive review

Malik, S., Asghar, M., & Waheed, Y. (2024) · Vaccine X · doi:10.1016/j.jvacx.2024.100452 · Cited by 19 · see citing works

Discovery of New Potent anti-MERS CoV Fusion Inhibitors

Kandeel, M. K., Yamamoto, M., Park, B. K., Al-Taher, A. Y., Watanabe, A., Gohda, J., Kawaguchi, Y., Oh‐hashi, K., Kwon, H., & Inoue, J. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.685161 · Cited by 18 · see citing works

Glycan-modified interfaces in biosensing: an electrochemical approach

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Inhibitory antibodies identify unique sites of therapeutic vulnerability in rhinovirus and other enteroviruses

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Broadly Neutralizing Antibodies to SARS-CoV-2 Provide Novel Insights Into the Neutralization of Variants and Other Human Coronaviruses

Bajpai, P., Singh, V., Chandele, A., & Kumar, S. (2022) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2022.928279 · Cited by 16 · see citing works

Mosaic quadrivalent influenza vaccine single nanoparticle characterization

Yang, R. S., Traver, M. K., Barefoot, N. Z., Stephens, T., Alabanza, C., Manzella‐Lapeira, J., Zou, G., Wolff, J. J., Li, Y., Resto, M., et al. (2024) · Scientific Reports · doi:10.1038/s41598-024-54876-2 · Cited by 16 · see citing works

Nanoscale Pathogens Treated with Nanomaterial-Like Peptides: A Platform Technology Appropriate for Future Pandemics

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Rational design of cyclic peptides, with an emphasis on bicyclic peptides

Rowland, C. E., Bezerra, G. A., & Skynner, M. J. (2025) · Current Opinion in Structural Biology · doi:10.1016/j.sbi.2025.103025 · Cited by 12 · see citing works

In Silico Structure-Based Prediction of Receptor–Ligand Binding Affinity: Current Progress and Challenges

Panday, S. K., & Ghosh, I. (2019) · Challenges and advances in computational chemistry and physics · doi:10.1007/978-3-030-05282-9_5 · Cited by 13 · see citing works

Prime-Boost Vaccination With a Novel Hemagglutinin Protein Produced in Bacteria Induces Neutralizing Antibody Responses Against H5-Subtype Influenza Viruses in Commercial Chickens

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Neutralizing antibodies to block viral entry and for identification of entry inhibitors

Tam, E.-H., Peng, Y., Cheah, M. X. Y., Yan, C., & Xiao, T. (2024) · Antiviral Research · doi:10.1016/j.antiviral.2024.105834 · Cited by 12 · see citing works

Dynamics of hemagglutinin-mediated membrane fusion

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Robust de novo design of protein binding proteins from target structural information alonePreprint

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Bypassing the Need for Cell Permeabilization: Nanobody CDR3 Peptide Improves Binding on Living Bacteria

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De novo design of D-peptide ligands: Application to influenza virus hemagglutinin

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Targeting the Respiratory Syncytial Virus N 0 -P Complex with Constrained α-Helical Peptides in Cells and Mice

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Structural Insights for Anti-Influenza Vaccine Design

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Recent advances in materials science: a reinforced approach toward challenges against COVID-19

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Discovery of a Novel Tetrapeptide against Influenza A Virus: Rational Design, Synthesis, Bioactivity Evaluation and Computational Studies

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Inhibition of H1 and H5 Influenza A Virus Entry by Diverse Macrocyclic Peptides Targeting the Hemagglutinin Stem Region

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Molecular Modeling of Viral Type I Fusion Proteins: Inhibitors of Influenza Virus Hemagglutinin and the Spike Protein of Coronavirus

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Small molecule–constrained paratope mimetic bicyclic peptides as potent inhibitors of group 1 and 2 influenza A virus hemagglutinins

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N-benzyl 4,4-disubstituted piperidines as a potent class of influenza H1N1 virus inhibitors showing a novel mechanism of hemagglutinin fusion peptide interaction

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Inhibition of Influenza A Virus Infection In Vitro by Peptides Designed In Silico

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Identification of Novel Fusion Inhibitors of Influenza A Virus by Chemical Genetics

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Hacking hemagglutinin

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