Beckmann, Roland

Collided ribosomes form a unique structural interface to induce Hel2-driven quality control pathways

Ikeuchi, K., Tesina, P., Matsuo, Y., Sugiyama, T., Cheng, J., Saeki, Y., Tanaka, K., Becker, T., Beckmann, R., & Inada, T. (2019) · The EMBO Journal

RNA and protein synthesis mechanismsUbiquitin and proteasome pathways

Cited by 315

Cryo-EM structure of the ribosome-SecYE complex in the membrane environment.

Frauenfeld, J., Gumbart, J., Sluis, E. O. V. D., Funes, S., Gartmann, M., Beatrix, B., Mielke, T., Berninghausen, O., Becker, T., Schulten, K., et al. (2011) · Nature Structural & Molecular Biology

RNA and protein synthesis mechanismsAdvanced Electron Microscopy Techniques and Applications

Cited by 298

Structural basis for TetM-mediated tetracycline resistance

Dönhöfer, A., Franckenberg, S., Wickles, S., Berninghausen, O., Beckmann, R., & Wilson, D. N. (2012) · Proceedings of the National Academy of Sciences

RNA and protein synthesis mechanismsAntibiotic Resistance in Bacteria

Cited by 217

SecM-Stalled Ribosomes Adopt an Altered Geometry at the Peptidyl Transferase Center

Bhushan, S., Hoffmann, T., Seidelt, B., Frauenfeld, J., Mielke, T., Berninghausen, O., Wilson, D. N., & Beckmann, R. (2011) · PLoS Biology

RNA and protein synthesis mechanismsBacterial Genetics and Biotechnology

Cited by 154

RQT complex dissociates ribosomes collided on endogenous RQC substrate SDD1

Matsuo, Y., Tesina, P., Nakajima, S., Mizuno, M., Endo, A., Buschauer, R., Cheng, J., Shounai, O., Ikeuchi, K., Saeki, Y., et al. (2020) · Nature Structural & Molecular Biology

RNA and protein synthesis mechanismsUbiquitin and proteasome pathways

Cited by 150

Tetracenomycin X inhibits translation by binding within the ribosomal exit tunnel

Osterman, I. A., Wieland, M., Maviza, T. P., Lashkevich, K. A., Lukianov, D. A., Komarova, E. S., Zakalyukina, Y. V., Buschauer, R., Shiriaev, D. I., Leyn, S. A., et al. (2020) · Nature Chemical Biology

RNA and protein synthesis mechanismsMicrobial Natural Products and Biosynthesis

Cited by 75

Modulating co-translational protein folding by rational design and ribosome engineering

Ahn, M., Włodarski, T., Mitropoulou, A., Chan, S. H. S., Sidhu, H., Plessa, E., Becker, T. A., Budisa, N., Waudby, C. A., Beckmann, R., et al. (2022) · Nature Communications

RNA and protein synthesis mechanismsProtein Structure and Dynamics

Cited by 45

Partially inserted nascent chain unzips the lateral gate of the Sec translocon.

Kater, L., Frieg, B., Berninghausen, O., Gohlke, H., Beckmann, R., & Kedrov, A. (2019) · The EMBO Reports

RNA and protein synthesis mechanismsBacterial Genetics and Biotechnology

Cited by 43

Role of the cytosolic loop C2 and the C terminus of YidC in ribosome binding and insertion activity.

Geng, Y., Kedrov, A., Caumanns, J. J., Crevenna, A. H., Lamb, D. C., Beckmann, R., & Driessen, A. J. M. (2015) · Journal of Biological Chemistry

Bacterial Genetics and BiotechnologyRNA and protein synthesis mechanisms

Cited by 30

Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline

Li, X., Wang, M., Denk, T., Buschauer, R., Li, Y., Beckmann, R., & Cheng, J. (2024) · Nature Communications

RNA and protein synthesis mechanismsRNA modifications and cancer

Cited by 21

Concurrent remodelling of nucleolar 60S subunit precursors by the Rea1 ATPase and Spb4 RNA helicase

Mitterer, V., Thoms, M., Buschauer, R., Berninghausen, O., Hurt, E., & Beckmann, R. (2023) · eLife

RNA and protein synthesis mechanismsNuclear Structure and Function

Cited by 13

Concurrent remodelling of nucleolar 60S subunit precursors by the Rea1 ATPase and Spb4 RNA helicase

Mitterer, V., Thoms, M., Buschauer, R., Berninghausen, O., Hurt, E., & Beckmann, R. (2022) · eLife

RNA and protein synthesis mechanismsNuclear Structure and Function

Cited by 13