Dierssen, Mara

Cognitive deficits and associated neurological complications in individuals with Down's syndrome

Lott, I. T., & Dierssen, M. (2010) · The Lancet Neurology

Down syndrome and intellectual disability researchDementia and Cognitive Impairment Research

Cited by 484

Erbb4 Deletion from Fast-Spiking Interneurons Causes Schizophrenia-like Phenotypes

del Pino, I., García-Frigola, C., Dehorter, N., Brotons-Mas, J. R., Alvarez-Salvado, E., Martínez de Lagrán, M., Ciceri, G., Gabaldón, M. V., Moratal, D., Dierssen, M., et al. (2013) · Neuron

Schizophrenia research and treatmentNeuroscience and Neuropharmacology Research

Cited by 314

Targeting the endocannabinoid system in the treatment of fragile X syndrome

Busquets-Garcia, A., Gomis-González, M., Guegan, T., Agustín-Pavón, C., Pastor, A., Mato, S., Pérez-Samartín, A., Matute, C., de la Torre, R., Dierssen, M., et al. (2013) · Nature Medicine

Genetics and Neurodevelopmental DisordersCannabis and Cannabinoid Research

Cited by 241

Differential effects of environmental enrichment on behavior and learning of male and female Ts65Dn mice, a model for Down syndrome

Martı́nez-Cué, C., Baamonde, C., Lumbreras, M., Paz, J., Davisson, M. T., Schmidt, C., Dierssen, M., & Flórez, J. (2002) · Behavioural Brain Research

Down syndrome and intellectual disability researchMemory and Neural Mechanisms

Cited by 166

Hippocampal volume and neuronal number in Ts65Dn mice: a murine model of down syndrome.

Insausti, A. M., Megı́as, M., Crespo, D., Cruz-Orive, L. M., Dierssen, M., Vallina, T. F., Insausti, R., & Flórez, J. (1998) · Neuroscience Letters

Down syndrome and intellectual disability researchAlzheimer's disease research and treatments

Cited by 149

DNA methylation map of mouse and human brain identifies target genes in Alzheimer’s disease

Sanchez-Mut, J. V., Aso, E., Panayotis, N., Lott, I., Dierssen, M., Rabano, A., Urdinguio, R. G., Fernandez, A. F., Astudillo, A., Martin-Subero, J. I., et al. (2013) · Brain

Epigenetics and DNA MethylationAlzheimer's disease research and treatments

Cited by 144

Dyrk1A expression pattern supports specific roles of this kinase in the adult central nervous system

Martı́, E., Altafaj, X., Dierssen, M., de la Luna, S., Fotaki, V., Alvarez, M., Pérez-Riba, M., Ferrer, I., & Estivill, X. (2003) · Brain Research

Neurogenesis and neuroplasticity mechanismsNeuroscience and Neuropharmacology Research

Cited by 136

Fetal Down Syndrome Brains Exhibit Aberrant Levels of Neurotransmitters Critical for Normal Brain Development

Whittle, N., Sartori, S. B., Dierssen, M., Lubec, G., & Singewald, N. (2007) · Pediatrics

Down syndrome and intellectual disability researchGenetics and Neurodevelopmental Disorders

Cited by 127

Deficits of neuronal density in CA1 and synaptic density in the dentate gyrus, CA3 and CA1, in a mouse model of Down syndrome

Ayberk Kurt, M., Ilker Kafa, M., Dierssen, M., & Ceri Davies, D. (2004) · Brain Research

Down syndrome and intellectual disability researchGenetics and Neurodevelopmental Disorders

Cited by 126

A specific prelimbic-nucleus accumbens pathway controls resilience versus vulnerability to food addiction

Domingo-Rodriguez, L., Ruiz de Azua, I., Dominguez, E., Senabre, E., Serra, I., Kummer, S., Navandar, M., Baddenhausen, S., Hofmann, C., Andero, R., et al. (2020) · Nature Communications

Neurotransmitter Receptor Influence on BehaviorEating Disorders and Behaviors

Cited by 109

DYRK1A (Dual-Specificity Tyrosine-Phosphorylated and -Regulated Kinase 1A): A Gene with Dosage Effect During Development and Neurogenesis

Dierssen, M., & de Lagrán, M. M. (2006) · The Scientific World JOURNAL

Neurogenesis and neuroplasticity mechanismsGenetics and Neurodevelopmental Disorders

Cited by 97

Normalization of Dyrk1A expression by AAV2/1-shDyrk1A attenuates hippocampal-dependent defects in the Ts65Dn mouse model of down syndrome

Altafaj, X., Martín, E. D., Ortiz-Abalia, J., Valderrama, A., Lao-Peregrín, C., Dierssen, M., & Fillat, C. (2013) · Neurobiology of Disease

Down syndrome and intellectual disability researchAlzheimer's disease research and treatments

Cited by 75

Therapeutic approaches in the improvement of cognitive performance in Down syndrome

de la Torre, R., & Dierssen, M. (2012) · Progress in Brain Research

Down syndrome and intellectual disability researchAlzheimer's disease research and treatments

Cited by 53

State-of-the-art therapy for down syndrome

Lorenzon, N., Musoles‐Lleó, J., Turrisi, F., Gomis‐González, M., De La Torre, R., & Dierssen, M. (2023) · Developmental Medicine & Child Neurology

Down syndrome and intellectual disability researchAlzheimer's disease research and treatments

Cited by 22

Rethinking intellectual disability from neuro- to astro-pathology.

Fernández-Blanco, Á., & Dierssen, M. (2020) · International Journal of Molecular Sciences

Genetics and Neurodevelopmental DisordersDown syndrome and intellectual disability research

Cited by 19

A dynamic in vitro model of Down syndrome neurogenesis with trisomy 21 gene dosage correction

Bansal, P., Banda, E. C., Glatt-Deeley, H. R., Stoddard, C. E., Linsley, J. W., Arora, N., Deleschaux, C., Ahern, D. T., Kondaveeti, Y., Massey, R. E., et al. (2024) · Science Advances

Down syndrome and intellectual disability researchPluripotent Stem Cells Research

Cited by 13

Reduced cortical neurotransmitter receptor complex levels in fetal Down syndrome brain

Keihan Falsafi, S., Dierssen, M., Ghafari, M., Pollak, A., & Lubec, G. (2016) · Amino Acids

Down syndrome and intellectual disability researchNeuroscience and Neuropharmacology Research

Cited by 13