Kanno, Yuka

Interleukin-2 Signaling via STAT5 Constrains T Helper 17 Cell Generation

Laurence, A., Tato, C. M., Davidson, T. S., Kanno, Y., Chen, Z., Yao, Z., Blank, R. B., Meylan, F., Siegel, R., Hennighausen, L., et al. (2007) · Immunity

Psoriasis: Treatment and PathogenesisT-cell and B-cell Immunology

Cited by 1,507

Generation of pathogenic TH17 cells in the absence of TGF-β signalling

Ghoreschi, K., Laurence, A., Yang, X.-P., Tato, C. M., McGeachy, M. J., Konkel, J. E., Ramos, H. L., Wei, L., Davidson, T. S., Bouladoux, N., et al. (2010) · Nature

Psoriasis: Treatment and PathogenesisT-cell and B-cell Immunology

Cited by 1,388

JAK inhibition as a therapeutic strategy for immune and inflammatory diseases

Schwartz, D. M., Kanno, Y., Villarino, A., Ward, M., Gadina, M., & O'Shea, J. J. (2017) · Nature Reviews Drug Discovery

Cytokine Signaling Pathways and InteractionsRheumatoid Arthritis Research and Therapies

Cited by 1,266

Mechanisms and consequences of Jak–STAT signaling in the immune system

Villarino, A. V., Kanno, Y., & O'Shea, J. J. (2017) · Nature Immunology

Cytokine Signaling Pathways and InteractionsNF-κB Signaling Pathways

Cited by 1,221

Impaired TH17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome

Milner, J. D., Brenchley, J. M., Laurence, A., Freeman, A. F., Hill, B. J., Elias, K. M., Kanno, Y., Spalding, C., Elloumi, H. Z., Paulson, M. L., et al. (2008) · Nature

Immunodeficiency and Autoimmune DisordersT-cell and B-cell Immunology

Cited by 1,157

Global Mapping of H3K4me3 and H3K27me3 Reveals Specificity and Plasticity in Lineage Fate Determination of Differentiating CD4+ T Cells

Wei, G., Wei, L., Zhu, J., Zang, C., Hu-Li, J., Yao, Z., Cui, K., Kanno, Y., Roh, T.-Y., Watford, W. T., et al. (2009) · Immunity

T-cell and B-cell ImmunologyGenomics and Chromatin Dynamics

Cited by 1,152

Immunodeficiency and Chronic Myelogenous Leukemia-like Syndrome in Mice with a Targeted Mutation of the ICSBP Gene

Holtschke, T., Löhler, J., Kanno, Y., Fehr, T., Giese, N., Rosenbauer, F., Lou, J., Knobeloch, K.-P., Gabriele, L., Waring, J. F., et al. (1996) · Cell

interferon and immune responsesImmunodeficiency and Autoimmune Disorders

Cited by 644

Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5

Yang, X.-P., Ghoreschi, K., Steward-Tharp, S. M., Rodriguez-Canales, J., Zhu, J., Grainger, J. R., Hirahara, K., Sun, H.-W., Wei, L., Vahedi, G., et al. (2011) · Nature Immunology

Psoriasis: Treatment and PathogenesisT-cell and B-cell Immunology

Cited by 583

Transcriptional and Epigenetic Control of T Helper Cell Specification: Molecular Mechanisms Underlying Commitment and Plasticity

Kanno, Y., Vahedi, G., Hirahara, K., Singleton, K., & O'Shea, J. J. (2012) · Annual Review of Immunology

T-cell and B-cell ImmunologyGenomics and Chromatin Dynamics

Cited by 342

Developmental Acquisition of Regulomes Underlies Innate Lymphoid Cell Functionality

Shih, H.-Y., Sciumè, G., Mikami, Y., Guo, L., Sun, H.-W., Brooks, S. R., Urban, J. F., Davis, F. P., Kanno, Y., & O’Shea, J. J. (2016) · Cell

IL-33, ST2, and ILC PathwaysT-cell and B-cell Immunology

Cited by 334

Genomic views of STAT function in CD4+ T helper cell differentiation

O'Shea, J. J., Lahesmaa, R., Vahedi, G., Laurence, A., & Kanno, Y. (2011) · Nature Reviews Immunology

Cytokine Signaling Pathways and InteractionsT-cell and B-cell Immunology

Cited by 295

Intrinsic Transcriptional Activation-Inhibition Domains of the Polyomavirus Enhancer Binding Protein 2/Core Binding Factor α Subunit Revealed in the Presence of the β Subunit

Kanno, T., Kanno, Y., Chen, L.-F., Ogawa, E., Kim, W.-Y., & Ito, Y. (1998) · Molecular and Cellular Biology

Genomics and Chromatin DynamicsAcute Myeloid Leukemia Research

Cited by 192

The genomic structure of the murine ICSBP gene reveals the presence of the gamma interferon-responsive element, to which an ISGF3 alpha subunit (or similar) molecule binds.

Kanno, Y., Kozak, C. A., Schindler, C., Driggers, P. H., Ennist, D. L., Gleason, S. L., Darnell, J. E., & Ozato, K. (1993) · Molecular and Cellular Biology

interferon and immune responsesCytokine Signaling Pathways and Interactions

Cited by 180

Gata6+ Pericardial Cavity Macrophages Relocate to the Injured Heart and Prevent Cardiac Fibrosis

Deniset, J. F., Belke, D., Lee, W.-Y., Jorch, S. K., Deppermann, C., Hassanabad, A. F., Turnbull, J. D., Teng, G., Rozich, I., Hudspeth, K., et al. (2019) · Immunity

Cardiac Fibrosis and RemodelingCongenital heart defects research

Cited by 178

Interleukin-23-Induced Transcription Factor Blimp-1 Promotes Pathogenicity of T Helper 17 Cells

Jain, R., Chen, Y., Kanno, Y., Joyce-Shaikh, B., Vahedi, G., Hirahara, K., Blumenschein, W. M., Sukumar, S., Haines, C. J., Sadekova, S., et al. (2016) · Immunity

Psoriasis: Treatment and PathogenesisT-cell and B-cell Immunology

Cited by 167

Immune cell-specific amplification of interferon signaling by the IRF-4/8-PU. 1 complex

Kanno, Y., Levi, B.-Z., Tamura, T., & Ozato, K. (2005) · Journal of Interferon & Cytokine Research

interferon and immune responsesCytokine Signaling Pathways and Interactions

Cited by 128

Expression of IFN regulatory factor family proteins in lymphocytes. Induction of Stat-1 and IFN consensus sequence binding protein expression by T cell activation

Nelson, N., Kanno, Y., Hong, C., Contursi, C., Fujita, T., Fowlkes, B. J., O’Connell, E., Hu-Li, J., Paul, W. E., Jankovic, D., et al. (1996) · The Journal of Immunology

interferon and immune responsesCytokine Signaling Pathways and Interactions

Cited by 110

A mouse model of HIES reveals pro- and anti-inflammatory functions of STAT3

Steward-Tharp, S. M., Laurence, A., Kanno, Y., Kotlyar, A., Villarino, A. V., Sciume, G., Kuchen, S., Resch, W., Wohlfert, E. A., Jiang, K., et al. (2014) · Blood

Immunodeficiency and Autoimmune DisordersCytokine Signaling Pathways and Interactions

Cited by 87

SnapShot: Jak-STAT Signaling II

Villarino, A. V., Gadina, M., O’Shea, J. J., & Kanno, Y. (2020) · Cell

Cytokine Signaling Pathways and InteractionsNF-κB Signaling Pathways

Cited by 85

A Novel Transcript Encoding an N-Terminally Truncated AML1/PEBP2αB Protein Interferes with Transactivation and Blocks Granulocytic Differentiation of 32Dcl3 Myeloid Cells

Zhang, Y.-W., Bae, S.-C., Huang, G., Fu, Y.-X., Lu, J., Ahn, M.-Y., Kanno, Y., Kanno, T., & Ito, Y. (1997) · Molecular and Cellular Biology

Acute Myeloid Leukemia ResearchRetinoids in leukemia and cellular processes

Cited by 77

Gamma Interferon Triggers Interaction between ICSBP (IRF-8) and TEL, Recruiting the Histone Deacetylase HDAC3 to the Interferon-Responsive Element

Kuwata, T., Gongora, C., Kanno, Y., Sakaguchi, K., Tamura, T., Kanno, T., Basrur, V., Martinez, R., Appella, E., Golub, T., et al. (2002) · Molecular and Cellular Biology

interferon and immune responsesGenomics and Chromatin Dynamics

Cited by 69

A dominant negative mutant of an IFN regulatory factor family protein inhibits both type I and type II IFN-stimulated gene expression and antiproliferative activity of IFNs

Thornton, A. M., Ogryzko, V. V., Dent, A., Sharf, R., Levi, B. Z., Kanno, Y., Staudt, L. M., Howard, B. H., & Ozato, K. (1996) · The Journal of Immunology

interferon and immune responsesCytokine Signaling Pathways and Interactions

Cited by 25