Goldman, James E.

Loss of mTOR-Dependent Macroautophagy Causes Autistic-like Synaptic Pruning Deficits

Tang, G., Gudsnuk, K., Kuo, S.-H., Cotrina, M. L., Rosoklija, G., Sosunov, A., Sonders, M. S., Kanter, E., Castagna, C., Yamamoto, A., et al. (2014) · Neuron

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 1,146

White matter changes in Alzheimer’s disease: A focus on myelin and oligodendrocytes

Nasrabady, S. E., Rizvi, B., Goldman, J. E., & Brickman, A. M. (2018) · Acta Neuropathologica Communications

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 723

Endogenous progenitors remyelinate demyelinated axons in the adult CNS

Gensert, J. M., & Goldman, J. E. (1997) · Neuron

Neurogenesis and neuroplasticity mechanismsMultiple Sclerosis Research Studies

Cited by 544

Efficient Generation of Myelinating Oligodendrocytes from Primary Progressive Multiple Sclerosis Patients by Induced Pluripotent Stem Cells

Douvaras, P., Wang, J., Zimmer, M., Hanchuk, S., O’Bara, M. A., Sadiq, S., Sim, F. J., Goldman, J., & Fossati, V. (2014) · Stem Cell Reports

Pluripotent Stem Cells ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 302

Single-nucleus RNA-seq identifies Huntington disease astrocyte states

Al-Dalahmah, O., Sosunov, A. A., Shaik, A., Ofori, K., Liu, Y., Vonsattel, J. P., Adorjan, I., Menon, V., & Goldman, J. E. (2020) · Acta Neuropathologica Communications

Genetic Neurodegenerative DiseasesSingle-cell and spatial transcriptomics

Cited by 264

Alexander Disease

Messing, A., Brenner, M., Feany, M. B., Nedergaard, M., & Goldman, J. E. (2012) · The Journal of Neuroscience

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 250

Oligodendrocytes and Progenitors Become Progressively Depleted within Chronically Demyelinated Lesions

Mason, J. L., Toews, A., Hostettler, J. D., Morell, P., Suzuki, K., Goldman, J. E., & Matsushima, G. K. (2004) · The American Journal of Pathology

Multiple Sclerosis Research StudiesNeurogenesis and neuroplasticity mechanisms

Cited by 212

Mitochondrial abnormalities in temporal lobe of autistic brain

Tang, G., Gutierrez Rios, P., Kuo, S.-H., Akman, H. O., Rosoklija, G., Tanji, K., Dwork, A., Schon, E. A., DiMauro, S., Goldman, J., et al. (2013) · Neurobiology of Disease

Autism Spectrum Disorder ResearchMitochondrial Function and Pathology

Cited by 194

Phenotypic Heterogeneity and Plasticity of Isocortical and Hippocampal Astrocytes in the Human Brain

Sosunov, A. A., Wu, X., Tsankova, N. M., Guilfoyle, E., McKhann, G. M., & Goldman, J. E. (2014) · The Journal of Neuroscience

Neuroscience and Neuropharmacology ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 185

Insulin-like growth factor (IGF) signaling through type 1 IGF receptor plays an important role in remyelination

Mason, J. L., Xuan, S., Dragatsis, I., Efstratiadis, A., & Goldman, J. E. (2003) · The Journal of Neuroscience

Neurogenesis and neuroplasticity mechanismsMultiple Sclerosis Research Studies

Cited by 177

Border-associated macrophages mediate the neuroinflammatory response in an alpha-synuclein model of Parkinson disease

Schonhoff, A. M., Figge, D. A., Williams, G. P., Jurkuvenaite, A., Gallups, N. J., Childers, G. M., Webster, J. M., Standaert, D. G., Goldman, J. E., & Harms, A. S. (2023) · Nature Communications

Neuroinflammation and Neurodegeneration MechanismsParkinson's Disease Mechanisms and Treatments

Cited by 161

Growth Kinetics, Cell Shape, and the Cytoskeleton of Primary Astrocyte Cultures

Goldman, J. E., & Chiu, F. (1984) · Journal of Neurochemistry

Cellular Mechanics and InteractionsSkin and Cellular Biology Research

Cited by 98

A Clinicopathological Comparison of Community-Based and Clinic-Based Cohorts of Patients With Dementia

Massoud, F., Devi, G., Stern, Y., Lawton, A., Goldman, J. E., Liu, Y., Chin, S. S., & Mayeux, R. (1999) · Archives of Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 91

Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation

Lim, R. G., Al-Dalahmah, O., Wu, J., Gold, M. P., Reidling, J. C., Tang, G., Adam, M., Dansu, D. K., Park, H.-J., Casaccia, P., et al. (2022) · Nature Communications

Genetic Neurodegenerative DiseasesNeurogenesis and neuroplasticity mechanisms

Cited by 84

Soluble amyloid beta levels are elevated in the white matter of Alzheimer’s patients, independent of cortical plaque severity

Collins-Praino, L. E., Francis, Y. I., Griffith, E. Y., Wiegman, A. F., Urbach, J., Lawton, A., Honig, L. S., Cortes, E., Vonsattel, J. P. G., Canoll, P. D., et al. (2014) · Acta Neuropathologica Communications

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 79