Turley, Shannon J.

TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells

Mariathasan, S., Turley, S. J., Nickles, D., Castiglioni, A., Yuen, K., Wang, Y., Kadel III, E. E., Koeppen, H., Astarita, J. L., Cubas, R., et al. (2018) · Nature

Cancer Immunotherapy and BiomarkersTGF-β signaling in diseases

Cited by 5,400

Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages

the Immunological Genome Consortium, Gautier, E. L., Shay, T., Miller, J., Greter, M., Jakubzick, C., Ivanov, S., Helft, J., Chow, A., Elpek, K. G., et al. (2012) · Nature Immunology

Immune cells in cancerPhagocytosis and Immune Regulation

Cited by 1,972

The Immunological Genome Project: networks of gene expression in immune cells

The Immunological Genome Project Consortium, Heng, T. S. P., Painter, M. W., Elpek, K., Lukacs-Kornek, V., Mauermann, N., Turley, S. J., Koller, D., Kim, F. S., Wagers, A. J., et al. (2008) · Nature Immunology

Bioinformatics and Genomic NetworksGenomics and Chromatin Dynamics

Cited by 1,864

Immunological hallmarks of stromal cells in the tumour microenvironment

Turley, S. J., Cremasco, V., & Astarita, J. L. (2015) · Nature Reviews Immunology

Cancer Immunotherapy and BiomarkersImmune cells in cancer

Cited by 1,140

TGFβ biology in cancer progression and immunotherapy

Derynck, R., Turley, S. J., & Akhurst, R. J. (2021) · Nature Reviews Clinical Oncology

TGF-β signaling in diseasesCancer Immunotherapy and Biomarkers

Cited by 944

Single-cell RNA sequencing reveals stromal evolution into LRRC15(+) myofibroblasts as a determinant of patient response to cancer immunotherapy

Dominguez, C. X., Müller, S., Keerthivasan, S., Koeppen, H., Hung, J., Gierke, S., Breart, B., Foreman, O., Bainbridge, T. W., Castiglioni, A., et al. (2020) · Cancer Discovery

Pancreatic and Hepatic Oncology ResearchCancer Immunotherapy and Biomarkers

Cited by 857

Mesothelial cell-derived antigen-presenting cancer-associated fibroblasts induce expansion of regulatory T cells in pancreatic cancer

Huang, H., Wang, Z., Zhang, Y., Pradhan, R. N., Ganguly, D., Chandra, R., Murimwa, G., Wright, S., Gu, X., Maddipati, R., et al. (2022) · Cancer Cell

Pancreatic and Hepatic Oncology ResearchCancer Immunotherapy and Biomarkers

Cited by 542

Fibroblast-macrophage reciprocal interactions in health, fibrosis, and cancer

Buechler, M. B., Fu, W., & Turley, S. J. (2021) · Immunity

Immune cells in cancerCardiac Fibrosis and Remodeling

Cited by 494

Th17 Cells Induce Ectopic Lymphoid Follicles in Central Nervous System Tissue Inflammation

Peters, A., Pitcher, L. A., Sullivan, J. M., Mitsdoerffer, M., Acton, S. E., Franz, B., Wucherpfennig, K., Turley, S., Carroll, M. C., Sobel, R. A., et al. (2011) · Immunity

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

Cited by 480

LRRC15(+) myofibroblasts dictate the stromal setpoint to suppress tumour immunity

Krishnamurty, A. T., Shyer, J. A., Thai, M., Gandham, V., Buechler, M. B., Yang, Y. A., Pradhan, R. N., Wang, A. W., Sanchez, P. L., Qu, Y., et al. (2022) · Nature

Pancreatic and Hepatic Oncology ResearchTGF-β signaling in diseases

Cited by 436

In vivo discovery of immunotherapy targets in the tumour microenvironment

Zhou, P., Shaffer, D. R., Alvarez Arias, D. A., Nakazaki, Y., Pos, W., Torres, A. J., Cremasco, V., Dougan, S. K., Cowley, G. S., Elpek, K., et al. (2014) · Nature

Cancer Immunotherapy and BiomarkersT-cell and B-cell Immunology

Cited by 237

Integration of Th17- and lymphotoxin-derived signals initiates meningeal-resident stromal cell remodeling to propagate neuroinflammation.

Pikor, N. B., Astarita, J. L., Summers-Deluca, L., Galicia, G., Qu, J., Ward, L. A., Armstrong, S., Dominguez, C. X., Malhotra, D., Heiden, B., et al. (2015) · Immunity

Multiple Sclerosis Research StudiesT-cell and B-cell Immunology

Cited by 229

Impaired thymic tolerance to α-myosin directs autoimmunity to the heart in mice and humans

Lv, H., Havari, E., Pinto, S., Gottumukkala, R. V. S. R. K., Cornivelli, L., Raddassi, K., Matsui, T., Rosenzweig, A., Bronson, R. T., Smith, R., et al. (2011) · Journal of Clinical Investigation

Viral Infections and Immunology ResearchT-cell and B-cell Immunology

Cited by 228

Stromal and hematopoietic cells in secondary lymphoid organs: partners in immunity

Malhotra, D., Fletcher, A. L., & Turley, S. J. (2013) · Immunological Reviews

T-cell and B-cell ImmunologyLymphatic System and Diseases

Cited by 152

Mature natural killer cells with phenotypic and functional alterations accumulate upon sustained stimulation with IL-15/IL-15Rα complexes

Elpek, K. G., Rubinstein, M. P., Bellemare-Pelletier, A., Goldrath, A. W., & Turley, S. J. (2010) · Proceedings of the National Academy of Sciences

Immune Cell Function and InteractionT-cell and B-cell Immunology

Cited by 130

Fibroblastic Reticular Cells: Organization and Regulation of the T Lymphocyte Life Cycle

Brown, F. D., & Turley, S. J. (2015) · The Journal of Immunology

T-cell and B-cell ImmunologyImmunotherapy and Immune Responses

Cited by 129

A short field guide to fibroblast function in immunity

Buechler, M. B., & Turley, S. J. (2018) · Seminars in Immunology

T-cell and B-cell ImmunologyImmune Response and Inflammation

Cited by 121

Lymph node stroma broaden the peripheral tolerance paradigm

Fletcher, A. L., Malhotra, D., & Turley, S. J. (2011) · Trends in Immunology

T-cell and B-cell ImmunologyImmunotherapy and Immune Responses

Cited by 120

Scalable querying of human cell atlases via a foundational model reveals commonalities across fibrosis-associated macrophages

Heimberg, G., Kuo, T., DePianto, D., Heigl, T., Diamant, N., Salem, O., Scalia, G., Biancalani, T., Turley, S., Rock, J., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory)

Single-cell and spatial transcriptomicsGene expression and cancer classification

Cited by 40