Yu, Hua

STATs in cancer inflammation and immunity: a leading role for STAT3

Yu, H., Pardoll, D., & Jove, R. (2009) · Nature reviews. Cancer

Cytokine Signaling Pathways and InteractionsImmune cells in cancer

Cited by 4,383

The STATs of cancer — new molecular targets come of age

Yu, H., & Jove, R. (2004) · Nature Reviews Cancer

Cytokine Signaling Pathways and InteractionsProtein Tyrosine Phosphatases

Cited by 2,278

Revisiting STAT3 signalling in cancer: new and unexpected biological functions

Yu, H., Lee, H., Herrmann, A., Buettner, R., & Jove, R. (2014) · Nature Reviews Cancer

Cytokine Signaling Pathways and InteractionsTGF-β signaling in diseases

Cited by 2,137

Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis

Niu, G., Wright, K. L., Huang, M., Song, L., Haura, E., Turkson, J., Zhang, S., Wang, T., Sinibaldi, D., Coppola, D., et al. (2002) · Oncogene

Angiogenesis and VEGF in CancerCytokine Signaling Pathways and Interactions

Cited by 1,207

AAV5–Factor VIII Gene Transfer in Severe Hemophilia A

Rangarajan, S., Walsh, L., Lester, W., Perry, D., Madan, B., Laffan, M., Yu, H., Vettermann, C., Pierce, G. F., Wong, W. Y., et al. (2017) · New England Journal of Medicine

Hemophilia Treatment and ResearchVirus-based gene therapy research

Cited by 694

Persistently Activated Stat3 Maintains Constitutive NF-κB Activity in Tumors

Lee, H., Herrmann, A., Deng, J.-H., Kujawski, M., Niu, G., Li, Z., Forman, S., Jove, R., Pardoll, D. M., & Yu, H. (2009) · Cancer Cell

NF-κB Signaling PathwaysCytokine Signaling Pathways and Interactions

Cited by 683

Roles of activated Src and Stat3 signaling in melanoma tumor cell growth

Niu, G., Bowman, T., Huang, M., Shivers, S., Reintgen, D., Daud, A., Chang, A., Kraker, A., Jove, R., & Yu, H. (2002) · Oncogene

Cytokine Signaling Pathways and InteractionsMelanoma and MAPK Pathways

Cited by 432

STAT3-induced S1PR1 expression is crucial for persistent STAT3 activation in tumors

Lee, H., Deng, J., Kujawski, M., Yang, C., Liu, Y., Herrmann, A., Kortylewski, M., Horne, D., Somlo, G., Forman, S., et al. (2010) · Nature Medicine

Cytokine Signaling Pathways and InteractionsSphingolipid Metabolism and Signaling

Cited by 395

A Critical Role for Stat3 Signaling in Immune Tolerance

Cheng, F., Wang, H.-W., Cuenca, A., Huang, M., Ghansah, T., Brayer, J., Kerr, W. G., Takeda, K., Akira, S., Schoenberger, S. P., et al. (2003) · Immunity

T-cell and B-cell ImmunologyCytokine Signaling Pathways and Interactions

Cited by 377

Activation of c-Src by receptor tyrosine kinases in human colon cancer cells with high metastatic potential

Mao, W., Irby, R., Coppola, D., Fu, L., Wloch, M., Turner, J., Yu, H., Garcia, R., Jove, R., & Yeatman, T. J. (1997) · Oncogene

Protein Kinase Regulation and GTPase SignalingHER2/EGFR in Cancer Research

Cited by 200

Inhibition of constitutive signal transducer and activator of transcription 3 activation by novel platinum complexes with potent antitumor activity

Turkson, J., Zhang, S., Palmer, J., Kay, H., Stanko, J., Mora, L. B., Sebti, S., Yu, H., & Jove, R. (2004) · Molecular Cancer Therapeutics

Metal complexes synthesis and propertiesCytokine Signaling Pathways and Interactions

Cited by 188

Stat3 Activity in Melanoma Cells Affects Migration of Immune Effector Cells and Nitric Oxide-Mediated Antitumor Effects

Burdelya, L., Kujawski, M., Niu, G., Zhong, B., Wang, T., Zhang, S., Kortylewski, M., Shain, K., Kay, H., Djeu, J., et al. (2005) · The Journal of Immunology

Cytokine Signaling Pathways and InteractionsImmune cells in cancer

Cited by 131

Toll-like receptor 9 activation of signal transducer and activator of transcription 3 constrains its agonist-based immunotherapy

Kortylewski, M., Kujawski, M., Herrmann, A., Yang, C., Wang, L., Liu, Y., Salcedo, R., & Yu, H. (2009) · Cancer Research

Cytokine Signaling Pathways and InteractionsImmunotherapy and Immune Responses

Cited by 122