Pang, Zhiping P.

Direct conversion of fibroblasts to functional neurons by defined factors

Vierbuchen, T., Ostermeier, A., Pang, Z. P., Kokubu, Y., Südhof, T. C., & Wernig, M. (2010) · Nature

Pluripotent Stem Cells ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 3,017

A dual-Ca2+-sensor model for neurotransmitter release in a central synapse

Sun, J., Pang, Z. P., Qin, D., Fahim, A. T., Adachi, R., & Südhof, T. C. (2007) · Nature

Neuroscience and Neuropharmacology ResearchCellular transport and secretion

Cited by 357

Synaptotagmin-1 functions as a Ca2+ sensor for spontaneous release

Xu, J., Pang, Z. P., Shin, O.-H., & Südhof, T. C. (2009) · Nature Neuroscience

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 274

Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis

Shin, O.-H., Lu, J., Rhee, J.-S., Tomchick, D. R., Pang, Z. P., Wojcik, S. M., Camacho-Perez, M., Brose, N., Machius, M., Rizo, J., et al. (2010) · Nature Structural & Molecular Biology

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 243

OLIG2 Drives Abnormal Neurodevelopmental Phenotypes in Human iPSC-Based Organoid and Chimeric Mouse Models of Down Syndrome

Xu, R., Brawner, A. T., Li, S., Liu, J.-J., Kim, H., Xue, H., Pang, Z. P., Kim, W.-Y., Hart, R. P., Liu, Y., et al. (2019) · Cell Stem Cell

Down syndrome and intellectual disability researchNeurogenesis and neuroplasticity mechanisms

Cited by 193

Type-I-interferon signaling drives microglial dysfunction and senescence in human iPSC models of Down syndrome and Alzheimer’s disease

Jin, M., Xu, R., Wang, L., Alam, M. M., Ma, Z., Zhu, S., Martini, A. C., Jadali, A., Bernabucci, M., Xie, P., et al. (2022) · Cell Stem Cell

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 174

Allele-specific open chromatin in human iPSC neurons elucidates functional disease variants

Zhang, S., Zhang, H., Zhou, Y., Qiao, M., Zhao, S., Kozlova, A., Shi, J., Sanders, A. R., Wang, G., Luo, K., et al. (2020) · Science

Genomics and Chromatin DynamicsGenetic Associations and Epidemiology

Cited by 127

Sequential regulatory loops as key gatekeepers for neuronal reprogramming in human cells

Xue, Y., Qian, H., Hu, J., Zhou, B., Zhou, Y., Hu, X., Karakhanyan, A., Pang, Z., & Fu, X.-D. (2016) · Nature Neuroscience

Pluripotent Stem Cells ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 118

Lipid-Anchored SNAREs Lacking Transmembrane Regions Fully Support Membrane Fusion during Neurotransmitter Release

Zhou, P., Bacaj, T., Yang, X., Pang, Z. P., & Südhof, T. C. (2013) · Neuron

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 114

A Gain-of-Function Mutation in Synaptotagmin-1 Reveals a Critical Role of Ca 2+ -Dependent Soluble N -Ethylmaleimide-Sensitive Factor Attachment Protein Receptor Complex Binding in Synaptic Exocytosis

Pang, Z. P., Shin, O.-H., Meyer, A. C., Rosenmund, C., & Südhof, T. C. (2006) · The Journal of Neuroscience

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 113

Activation of arcuate nucleus glucagon-like peptide-1 receptor-expressing neurons suppresses food intake

Singh, I., Wang, L., Xia, B., Liu, J., Tahiri, A., El Ouaamari, A., Wheeler, M. B., & Pang, Z. P. (2022) · Cell & Bioscience

Regulation of Appetite and ObesityHypothalamic control of reproductive hormones

Cited by 98

Glucose-sensing glucagon-like peptide-1 receptor neurons in the dorsomedial hypothalamus regulate glucose metabolism

Huang, Z., Liu, L., Zhang, J., Conde, K., Phansalkar, J., Li, Z., Yao, L., Xu, Z., Wang, W., Zhou, J., et al. (2022) · Science Advances

Regulation of Appetite and ObesityPancreatic function and diabetes

Cited by 78

Chronic Stress Induces Maladaptive Behaviors by Activating Corticotropin-Releasing Hormone Signaling in the Mouse Oval Bed Nucleus of the Stria Terminalis

Hu, P., Liu, J., Maita, I., Kwok, C., Gu, E., Gergues, M. M., Kelada, F., Phan, M., Zhou, J.-N., Swaab, D. F., et al. (2020) · The Journal of Neuroscience

Stress Responses and CortisolNeuropeptides and Animal Physiology

Cited by 71

PICALM Alzheimer’s risk allele causes aberrant lipid droplets in microglia

Kozlova, A., Zhang, S., Sudwarts, A., Zhang, H., Smirnou, S., Byeon, S. K., Thapa, C., Sun, X., Stephenson, K., Zhao, X., et al. (2025) · Nature

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 53

Early-life stress alters affective behaviors in adult mice through persistent activation of CRH-BDNF signaling in the oval bed nucleus of the stria terminalis

Hu, P., Maita, I., Phan, M. L., Gu, E., Kwok, C., Dieterich, A., Gergues, M. M., Yohn, C. N., Wang, Y., Zhou, J.-N., et al. (2020) · Translational Psychiatry

Stress Responses and CortisolNeuropeptides and Animal Physiology

Cited by 49

Gq Protein-Coupled Membrane-Initiated Estrogen Signaling Rapidly Excites Corticotropin-Releasing Hormone Neurons in the Hypothalamic Paraventricular Nucleus in Female Mice

Hu, P., Liu, J., Yasrebi, A., Gotthardt, J. D., Bello, N. T., Pang, Z. P., & Roepke, T. A. (2016) · Endocrinology

Estrogen and related hormone effectsNeuroscience and Neuropharmacology Research

Cited by 40

Regulation of synaptic functions in central nervous system by endocrine hormones and the maintenance of energy homoeostasis

Pang, Z. P., & Han, W. (2012) · Bioscience Reports

Regulation of Appetite and ObesityNeuroscience and Neuropharmacology Research

Cited by 34

Multiple genes in a single GWAS risk locus synergistically mediate aberrant synaptic development and function in human neurons

Zhang, S., Zhang, H., Forrest, M. P., Zhou, Y., Sun, X., Bagchi, V. A., Kozlova, A., Santos, M. D., Piguel, N. H., Dionisio, L. E., et al. (2023) · Cell Genomics

Schizophrenia research and treatmentGenetic Associations and Epidemiology

Cited by 26