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Untitled work

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Cell-type specific global reprogramming of the transcriptome and epigenome in induced neurons with the 16p11.2 neuropsychiatric CNVs

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The Perspectives of Early Diagnosis of Schizophrenia Through the Detection of Epigenomics-Based Biomarkers in iPSC-Derived Neurons

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Genome-wide discovery of SLE genetic risk variant allelic enhancer activityPreprint

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3D genetic architecture of schizophrenia risk across three neuronal subtypes

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Functional implications of polygenic risk for schizophrenia in human neurons

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Leveraging allelic imbalance in accessible chromatin to prioritize putative causal variants

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Single-cell multiomics of neuron activation reveals context-specific genetics of brain disorders

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Epigenetic and Transcriptional Dysregulation in T cells of Patients with Atopic Dermatitis

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Starvation and Climate Change—How to Constrain Cancer Cell Epigenetic Diversity and Adaptability to Enhance Treatment Efficacy

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scVMAP: a comprehensive platform for integrating single-cell chromatin accessibility regions with causal variants

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Spatiotemporal dynamics of RERE in schizophrenia pathogenesis: insights from multi-omics and single-cell sequencing

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Developmental reprogramming underlies chemotherapy resistance in favorable-histology Wilms tumor

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Rethinking disomy: Autosomal expression bias

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Predicting Epigenomic Functions of Genetic Variants in the Context of Neurodevelopment via Deep Transfer LearningPreprint

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DeepGWAS: Enhance GWAS Signals for Neuropsychiatric Disorders via Deep Neural NetworkPreprint

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Schizophrenia Risk Mapping and Functional Engineering of the 3D Genome in Three Neuronal SubtypesPreprint

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Alzheimer’s disease protective allele of Clusterin modulates neuronal excitability through lipid-droplet-mediated neuron-glia communicationPreprint

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Human stem cell modeling of neuropsychiatric disorders: from polygenicity to convergence

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Better together: Non-additive interactions between schizophrenia risk genes

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Accurate, sensitive, and efficient chromatin accessibility quantification at target loci using UNIChro-seq

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ATAC-seq and psychiatric disorders

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Chromatin architecture in addiction circuitry elucidates biological mechanisms underlying cigarette smoking and alcohol use traitsPreprint

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Uncovering divergence in gene expression regulation in the adaptation of yeast to nitrogen scarcityPreprint

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Multiple genes in cis mediate the effects of a single chromatin accessibility variant on aberrant synaptic development and function in human neuronsPreprint

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Cell type-specific cis -regulatory divergence in gene expression and chromatin accessibility revealed by human-chimpanzee hybrid cellsPreprint

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Cell type-specific cis-regulatory divergence in gene expression and chromatin accessibility revealed by human-chimpanzee hybrid cellsPreprint

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Cell type-specific cis-regulatory divergence in gene expression and chromatin accessibility revealed by human-chimpanzee hybrid cellsPreprint

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Allele-specific open chromatin in human iPSC neurons elucidates functional non-coding disease variantsPreprint

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Effects of allele-specific open chromatin

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Open Chromatin Profiling in hiPSC-Derived Neurons Prioritizes Functional Noncoding Psychiatric Risk Variants and Highlights Neurodevelopmental Loci

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Open Chromatin Profiling Identifies Functional Noncoding Risk Variants In Human Ipsc Model of Psychiatric Disorders

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64. CHROMATIN ACCESSIBILITY MAPPING IN HIPSC IMPLICATES FUNCTIONAL GWAS RISK VARIANTS AND TARGET GENES FOR NEUROPSYCHIATRIC DISORDERS AND ALZHEIMER'S DISEASE

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