Merlino, Glenn

Dietary fiber and probiotics influence the gut microbiome and melanoma immunotherapy response

Spencer, C. N., McQuade, J. L., Gopalakrishnan, V., McCulloch, J. A., Vetizou, M., Cogdill, A. P., Khan, M. A. W., Zhang, X., White, M. G., Peterson, C. B., et al. (2021) · Science

Cancer Immunotherapy and BiomarkersGut microbiota and health

Cited by 966

Identification of essential genes for cancer immunotherapy

Patel, S. J., Sanjana, N. E., Kishton, R. J., Eidizadeh, A., Vodnala, S. K., Cam, M., Gartner, J. J., Jia, L., Steinberg, S. M., Yamamoto, T. N., et al. (2017) · Nature

Cancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses

Cited by 870

Preclinical Mouse Cancer Models: A Maze of Opportunities and Challenges

Day, C.-P., Merlino, G., & Van Dyke, T. (2015) · Cell

Cancer Cells and MetastasisAnimal testing and alternatives

Cited by 676

Lifetime exposure to a soluble TGF-β antagonist protects mice against metastasis without adverse side effects

Yang, Y.-A., Dukhanina, O., Tang, B., Mamura, M., Letterio, J. J., MacGregor, J., Patel, S. C., Khozin, S., Liu, Z.-Y., Green, J., et al. (2002) · Journal of Clinical Investigation

TGF-β signaling in diseasesMechanisms of cancer metastasis

Cited by 404

Melanoma induction by ultraviolet A but not ultraviolet B radiation requires melanin pigment

Noonan, F. P., Zaidi, M. R., Wolnicka-Glubisz, A., Anver, M. R., Bahn, J., Wielgus, A., Cadet, J., Douki, T., Mouret, S., Tucker, M. A., et al. (2012) · Nature Communications

Skin Protection and Agingmelanin and skin pigmentation

Cited by 331

Interferon-γ links ultraviolet radiation to melanomagenesis in mice

Zaidi, M. R., Davis, S., Noonan, F. P., Graff-Cherry, C., Hawley, T. S., Walker, R. L., Feigenbaum, L., Fuchs, E., Lyakh, L., Young, H. A., et al. (2011) · Nature

Cutaneous Melanoma Detection and ManagementMelanoma and MAPK Pathways

Cited by 293

Ultraviolet radiation and cutaneous malignant melanoma

Jhappan, C., Noonan, F. P., & Merlino, G. (2003) · Oncogene

Melanoma and MAPK PathwaysSkin Protection and Aging

Cited by 283

Ultraviolet B but not Ultraviolet A Radiation Initiates Melanoma

De Fabo, E. C., Noonan, F. P., Fears, T., & Merlino, G. (2004) · Cancer Research

Skin Protection and AgingMelanoma and MAPK Pathways

Cited by 279

Pancreatic gastrin stimulates islet differentiation of transforming growth factor alpha-induced ductular precursor cells.

Wang, T. C., Bonner-Weir, S., Oates, P. S., Chulak, M., Simon, B., Merlino, G. T., Schmidt, E. V., & Brand, S. J. (1993) · Journal of Clinical Investigation

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 270

A polymorphism in IRF4 affects human pigmentation through a tyrosinase-dependent MITF/TFAP2A pathway

Praetorius, C., Grill, C., Stacey, S. N., Metcalf, A. M., Gorkin, D. U., Robinson, K. C., Van Otterloo, E., Kim, R. S. Q., Bergsteinsdottir, K., Ogmundsdottir, M. H., et al. (2013) · Cell

melanin and skin pigmentationMelanoma and MAPK Pathways

Cited by 228

Gut microbiota dependent anti-tumor immunity restricts melanoma growth in Rnf5−/− mice

Li, Y., Tinoco, R., Elmén, L., Segota, I., Xian, Y., Fujita, Y., Sahu, A., Zarecki, R., Marie, K., Feng, Y., et al. (2019) · Nature Communications

Gut microbiota and healthCancer Immunotherapy and Biomarkers

Cited by 212

Toward a Drug Development Path That Targets Metastatic Progression in Osteosarcoma

Khanna, C., Fan, T. M., Gorlick, R., Helman, L. J., Kleinerman, E. S., Adamson, P. C., Houghton, P. J., Tap, W. D., Welch, D. R., Steeg, P. S., et al. (2014) · Clinical Cancer Research

Sarcoma Diagnosis and TreatmentCancer Cells and Metastasis

Cited by 178

mTORC1 activation blocks BrafV600E-induced growth arrest but is insufficient for melanoma formation

Damsky, W., Micevic, G., Meeth, K., Muthusamy, V., Curley, D. P., Santhanakrishnan, M., Erdelyi, I., Platt, J. T., Huang, L., Theodosakis, N., et al. (2015) · Cancer Cell

Melanoma and MAPK PathwaysPI3K/AKT/mTOR signaling in cancer

Cited by 142

Antagonistic Cross-Regulation between Sox9 and Sox10 Controls an Anti-tumorigenic Program in Melanoma

Shakhova, O., Cheng, P., Mishra, P. J., Zingg, D., Schaefer, S. M., Debbache, J., Häusel, J., Matter, C., Guo, T., Davis, S., et al. (2015) · PLOS Genetics

Melanoma and MAPK PathwaysCutaneous Melanoma Detection and Management

Cited by 111

Modeling metastasis biology and therapy in real time in the mouse lung

Mendoza, A., Hong, S.-H., Osborne, T., Khan, M. A., Campbell, K., Briggs, J., Eleswarapu, A., Buquo, L., Ren, L., Hewitt, S. M., et al. (2010) · Journal of Clinical Investigation

Cancer Cells and MetastasisMechanisms of cancer metastasis

Cited by 92