Melton, Douglas A.

Prospective isolation and global gene expression analysis of definitive and visceral endoderm

Sherwood, R. I., Jitianu, C., Cleaver, O., Shaywitz, D. A., Lamenzo, J. O., Chen, A. E., Golub, T. R., & Melton, D. A. (2007) · Developmental Biology

Developmental Biology and Gene RegulationPluripotent Stem Cells Research

Cited by 122

The promise of stem cell-derived islet replacement therapy

Melton, D. (2021) · Diabetologia

Pancreatic function and diabetesPluripotent Stem Cells Research

Cited by 96

Engineering human stem cell-derived islets to evade immune rejection and promote localized immune tolerance

Gerace, D., Zhou, Q., Kenty, J. H.-R., Veres, A., Sintov, E., Wang, X., Boulanger, K. R., Li, H., & Melton, D. A. (2023) · Cell Reports Medicine

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 88

A therapeutic convection–enhanced macroencapsulation device for enhancing β cell viability and insulin secretion

Yang, K., O’Cearbhaill, E. D., Liu, S. S., Zhou, A., Chitnis, G. D., Hamilos, A. E., Xu, J., Verma, M. K. S., Giraldo, J. A., Kudo, Y., et al. (2021) · Proceedings of the National Academy of Sciences

Pancreatic function and diabetesTissue Engineering and Regenerative Medicine

Cited by 58

Whole-genome CRISPR screening identifies genetic manipulations to reduce immune rejection of stem cell-derived islets

Sintov, E., Nikolskiy, I., Barrera, V., Hyoje-Ryu Kenty, J., Atkin, A. S., Gerace, D., Ho Sui, S. J., Boulanger, K., & Melton, D. A. (2022) · Stem Cell Reports

Pancreatic function and diabetesPluripotent Stem Cells Research

Cited by 45

Genetic manipulation of stress pathways can protect stem-cell-derived islets from apoptosis in vitro

Leite, N. C., Pelayo, G. C., & Melton, D. A. (2022) · Stem Cell Reports

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 36