Fan, Rong

The technological landscape and applications of single-cell multi-omics

Baysoy, A., Bai, Z., Satija, R., & Fan, R. (2023) · Nature Reviews Molecular Cell Biology

Single-cell and spatial transcriptomicsBioinformatics and Genomic Networks

Cited by 1,037

High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue

Liu, Y., Yang, M., Deng, Y., Su, G., Enninful, A., Guo, C. C., Tebaldi, T., Zhang, D., Kim, D., Bai, Z., et al. (2020) · Cell

Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies

Cited by 966

Spatial epigenome–transcriptome co-profiling of mammalian tissues

Zhang, D., Deng, Y., Kukanja, P., Agirre, E., Bartosovic, M., Dong, M., Ma, C., Ma, S., Su, G., Bao, S., et al. (2023) · Nature

Single-cell and spatial transcriptomicsGenomics and Chromatin Dynamics

Cited by 483

A clinical microchip for evaluation of single immune cells reveals high functional heterogeneity in phenotypically similar T cells

Ma, C., Fan, R., Ahmad, H., Shi, Q., Comin-Anduix, B., Chodon, T., Koya, R. C., Liu, C.-C., Kwong, G. A., Radu, C. G., et al. (2011) · Nature Medicine

Advanced Biosensing Techniques and ApplicationsMicrofluidic and Capillary Electrophoresis Applications

Cited by 441

High-plex protein and whole transcriptome co-mapping at cellular resolution with spatial CITE-seq

Liu, Y., DiStasio, M., Su, G., Asashima, H., Enninful, A., Qin, X., Deng, Y., Nam, J., Gao, F., Bordignon, P., et al. (2023) · Nature Biotechnology

Single-cell and spatial transcriptomicsBiotin and Related Studies

Cited by 418

Spatial profiling of chromatin accessibility in mouse and human tissues

Deng, Y., Bartosovic, M., Ma, S., Zhang, D., Kukanja, P., Xiao, Y., Su, G., Liu, Y., Qin, X., Rosoklija, G. B., et al. (2022) · Nature

Single-cell and spatial transcriptomicsGenomics and Chromatin Dynamics

Cited by 417

SenNet recommendations for detecting senescent cells in different tissues

Suryadevara, V., Hudgins, A. D., Rajesh, A., Pappalardo, A., Karpova, A., Dey, A. K., Hertzel, A., Agudelo, A., Rocha, A., Soygur, B., et al. (2024) · Nature Reviews Molecular Cell Biology

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 408

Spatial-CUT&Tag: Spatially resolved chromatin modification profiling at the cellular level

Deng, Y., Bartosovic, M., Kukanja, P., Zhang, D., Liu, Y., Su, G., Enninful, A., Bai, Z., Castelo-Branco, G., & Fan, R. (2022) · Science

Genomics and Chromatin DynamicsSingle-cell and spatial transcriptomics

Cited by 393

Transcriptomic taxonomy and neurogenic trajectories of adult human, macaque, and pig hippocampal and entorhinal cells

Franjic, D., Skarica, M., Ma, S., Arellano, J. I., Tebbenkamp, A. T. N., Choi, J., Xu, C., Li, Q., Morozov, Y. M., Andrijevic, D., et al. (2022) · Neuron

Neurogenesis and neuroplasticity mechanismsSingle-cell and spatial transcriptomics

Cited by 308

Deciphering spatial domains from spatial multi-omics with SpatialGlue

Long, Y., Ang, K. S., Sethi, R., Liao, S., Heng, Y., van Olst, L., Ye, S., Zhong, C., Xu, H., Zhang, D., et al. (2024) · Nature Methods

Single-cell and spatial transcriptomicsBioinformatics and Genomic Networks

Cited by 223

Synergistic IL-6 and IL-8 paracrine signalling pathway infers a strategy to inhibit tumour cell migration

Jayatilaka, H., Tyle, P., Chen, J. J., Kwak, M., Ju, J., Kim, H. J., Lee, J. S. H., Wu, P.-H., Gilkes, D. M., Fan, R., et al. (2017) · Nature Communications

Chemokine receptors and signalingCancer Cells and Metastasis

Cited by 177

Single-cell antigen-specific landscape of CAR T infusion product identifies determinants of CD19-positive relapse in patients with ALL

Bai, Z., Woodhouse, S., Zhao, Z., Arya, R., Govek, K., Kim, D., Lundh, S., Baysoy, A., Sun, H., Deng, Y., et al. (2022) · Science Advances

CAR-T cell therapy researchAcute Lymphoblastic Leukemia research

Cited by 166

Analysis of single-cell cytokine secretion reveals a role for paracrine signaling in coordinating macrophage responses to TLR4 stimulation

Xue, Q., Lu, Y., Eisele, M. R., Sulistijo, E. S., Khan, N., Fan, R., & Miller-Jensen, K. (2015) · Science Signaling

Immune Response and InflammationNeuroinflammation and Neurodegeneration Mechanisms

Cited by 143

Ex vivo Dynamics of Human Glioblastoma Cells in a Microvasculature‐on‐a‐Chip System Correlates with Tumor Heterogeneity and Subtypes

Xiao, Y., Kim, D., Dura, B., Zhang, K., Yan, R., Li, H., Han, E., Ip, J., Zou, P., Liu, J., et al. (2019) · Advanced Science

Glioma Diagnosis and TreatmentCancer Cells and Metastasis

Cited by 115

Co-detection and sequencing of genes and transcripts from the same single cells facilitated by a microfluidics platform

Han, L., Zi, X., Garmire, L. X., Wu, Y., Weissman, S. M., Pan, X., & Fan, R. (2014) · Scientific Reports

Microfluidic and Capillary Electrophoresis ApplicationsSingle-cell and spatial transcriptomics

Cited by 83

Advancing biological understanding of cellular senescence with computational multiomics

Li, S., Agudelo Garcia, P. A., Aliferis, C., Becich, M. J., Calyeca, J., Cosgrove, B. D., Elisseeff, J., Farzad, N., Fertig, E. J., Glass, C., et al. (2025) · Nature Genetics

Telomeres, Telomerase, and SenescenceSingle-cell and spatial transcriptomics

Cited by 40

Spatial transcriptome sequencing of FFPE tissues at cellular level

Liu, Y., Enninful, A., Deng, Y., & Fan, R. (2020) · bioRxiv (Cold Spring Harbor Laboratory)

Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies

Cited by 26

SINGLE CELL ANALYSIS, WHAT IS IN THE FUTURE?

Garmire, L. X., Yuan, G.-C., Fan, R., Yeo, G. W., & Quackenbush, J. (2018) · Biocomputing 2019

Single-cell and spatial transcriptomicsAdvanced Fluorescence Microscopy Techniques

Cited by 2