DeBerardinis, Ralph J.

Chemistry-First Approach for Nomination of Personalized Treatment in Lung Cancer

McMillan, E. A., Ryu, M.-J., Diep, C. H., Mendiratta, S., Clemenceau, J. R., Vaden, R. M., Kim, J.-H., Motoyaji, T., Covington, K. R., Peyton, M., et al. (2018) · Cell

Computational Drug Discovery MethodsLung Cancer Treatments and Mutations

Cited by 141

Tetrameric acetyl-CoA acetyltransferase 1 is important for tumor growth

Fan, J., Lin, R., Xia, S., Chen, D., Elf, S. E., Liu, S., Pan, Y., Xu, H., Qian, Z., Wang, M., et al. (2016) · Molecular Cell

Cancer, Hypoxia, and MetabolismBiochemical Acid Research Studies

Cited by 106

Metabolic dysregulation in monogenic disorders and cancer — finding method in madness

Erez, A., & DeBerardinis, R. J. (2015) · Nature Reviews Cancer

Metabolism and Genetic DisordersCancer, Hypoxia, and Metabolism

Cited by 105

Loss of a Negative Regulator of mTORC1 Induces Aerobic Glycolysis and Altered Fiber Composition in Skeletal Muscle

Dutchak, P. A., Estill-Terpack, S. J., Plec, A. A., Zhao, X., Yang, C., Chen, J., Ko, B., Deberardinis, R. J., Yu, Y., & Tu, B. P. (2018) · Cell Reports

Metabolism, Diabetes, and CancerPI3K/AKT/mTOR signaling in cancer

Cited by 53

Wilms Tumor in a Child with L-2-hydroxyglutaric Aciduria

Rogers, R. E., DeBerardinis, R. J., Klesse, L. J., Boriack, R. L., Margraf, L. R., & Rakheja, D. (2010) · Pediatric and Developmental Pathology

Metabolism and Genetic DisordersRenal and related cancers

Cited by 29

SNAT7 regulates mTORC1 via macropinocytosis

Meng, D., Yang, Q., Jeong, M.-H., Curukovic, A., Tiwary, S., Melick, C. H., Lama-Sherpa, T. D., Wang, H., Huerta-Rosario, M., Urquhart, G., et al. (2022) · Proceedings of the National Academy of Sciences

PI3K/AKT/mTOR signaling in cancerAutophagy in Disease and Therapy

Cited by 26

Abstract 4710: Evaluation of the glutaminase inhibitor CB-839 in non-small cell lung cancer

Boroughs, L. K., Chen, P.-H., Cai, L., Rodriguez, M., Zhang, W., Huffman, K. E., Byers, L. A., Girard, L., Gazdar, A. F., Heymach, J. V., et al. (2015) · Cancer Research

Cancer, Hypoxia, and MetabolismAmino Acid Enzymes and Metabolism

Cited by 1