Hoodless, Pamela A.

The emergent landscape of the mouse gut endoderm at single-cell resolution

Nowotschin, S., Setty, M., Kuo, Y.-Y., Liu, V., Garg, V., Sharma, R., Simon, C. S., Saiz, N., Gardner, R., Boutet, S. C., et al. (2019) · Nature

Single-cell and spatial transcriptomicsDevelopmental Biology and Gene Regulation

Cited by 383

Hematopoietic stem cells proliferate until after birth and show a reversible phase-specific engraftment defect

Bowie, M. B., McKnight, K. D., Kent, D. G., McCaffrey, L., Hoodless, P. A., & Eaves, C. J. (2006) · Journal of Clinical Investigation

Hematopoietic Stem Cell TransplantationMesenchymal stem cell research

Cited by 380

Slug is a direct Notch target required for initiation of cardiac cushion cellularization

Niessen, K., Fu, Y., Chang, L., Hoodless, P. A., McFadden, D., & Karsan, A. (2008) · The Journal of Cell Biology

Developmental Biology and Gene RegulationCongenital heart defects research

Cited by 363

FoxH1(Fast) functions to specify the anterior primitive streak in the mouse

Hoodless, P. A., Pye, M., Chazaud, C., Labbé, E., Attisano, L., Rossant, J., & Wrana, J. L. (2001) · Genes & Development

Developmental Biology and Gene RegulationPluripotent Stem Cells Research

Cited by 203

Genome-wide relationship between histone H3 lysine 4 mono- and tri-methylation and transcription factor binding

Robertson, A. G., Bilenky, M., Tam, A., Zhao, Y., Zeng, T., Thiessen, N., Cezard, T., Fejes, A. P., Wederell, E. D., Cullum, R., et al. (2008) · Genome Research

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 182

Formation of the definitive endoderm in mouse is a Smad2-dependent process

Tremblay, K. D., Hoodless, P. A., Bikoff, E. K., & Robertson, E. J. (2000) · Development

Developmental Biology and Gene RegulationTGF-β signaling in diseases

Cited by 178

Co-ordinating Notch, BMP, and TGF-β signaling during heart valve development

Garside, V. C., Chang, A. C., Karsan, A., & Hoodless, P. A. (2013) · Cellular and Molecular Life Sciences

Congenital heart defects researchDevelopmental Biology and Gene Regulation

Cited by 160

Global analysis of in vivo Foxa2-binding sites in mouse adult liver using massively parallel sequencing

Wederell, E. D., Bilenky, M., Cullum, R., Thiessen, N., Dagpinar, M., Delaney, A., Varhol, R., Zhao, Y., Zeng, T., Bernier, B., et al. (2008) · Nucleic Acids Research

Genomics and Chromatin DynamicsLiver physiology and pathology

Cited by 150

A mouse atlas of gene expression: Large-scale digital gene-expression profiles from precisely defined developing C57BL/6J mouse tissues and cells

Siddiqui, A. S., Khattra, J., Delaney, A. D., Zhao, Y., Astell, C., Asano, J., Babakaiff, R., Barber, S., Beland, J., Bohacec, S., et al. (2005) · Proceedings of the National Academy of Sciences

Genomics and Phylogenetic StudiesGene expression and cancer classification

Cited by 116

Locus co-occupancy, nucleosome positioning, and H3K4me1 regulate the functionality of FOXA2-, HNF4A-, and PDX1-bound loci in islets and liver

Hoffman, B. G., Robertson, G., Zavaglia, B., Beach, M., Cullum, R., Lee, S., Soukhatcheva, G., Li, L., Wederell, E. D., Thiessen, N., et al. (2010) · Genome Research

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 115

Hippo Signaling Influences HNF4A and FOXA2 Enhancer Switching during Hepatocyte Differentiation

Alder, O., Cullum, R., Lee, S., Kan, A. C., Wei, W., Yi, Y., Garside, V. C., Bilenky, M., Griffith, M., Morrissy, A. S., et al. (2014) · Cell Reports

Hippo pathway signaling and YAP/TAZGenomics and Chromatin Dynamics

Cited by 113

Hippi is essential for node cilia assembly and Sonic hedgehog signaling

Houde, C., Dickinson, R. J., Houtzager, V. M., Cullum, R., Montpetit, R., Metzler, M., Simpson, E. M., Roy, S., Hayden, M. R., Hoodless, P. A., et al. (2006) · Developmental Biology

Genetic and Kidney Cyst DiseasesHedgehog Signaling Pathway Studies

Cited by 98

Single-Cell Transcriptomics Reveals Early Emergence of Liver Parenchymal and Non-parenchymal Cell Lineages

Lotto, J., Drissler, S., Cullum, R., Wei, W., Setty, M., Bell, E. M., Boutet, S. C., Nowotschin, S., Kuo, Y.-Y., Garg, V., et al. (2020) · Cell

Single-cell and spatial transcriptomicsLiver physiology and pathology

Cited by 86

Hepatocyte Nuclear Factor 4‐Alpha Is Essential for the Active Epigenetic State at Enhancers in Mouse Liver

Thakur, A., Wong, J. C. H., Wang, E. Y., Lotto, J., Kim, D., Cheng, J., Mingay, M., Cullum, R., Moudgil, V., Ahmed, N., et al. (2019) · Hepatology

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 68

SOX9 modulates the expression of key transcription factors required for heart valve development

Garside, V. C., Cullum, R., Alder, O., Lu, D. Y., Vander Werff, R., Bilenky, M., Zhao, Y., Jones, S. J. M., Marra, M. A., Underhill, T. M., et al. (2015) · Development

Congenital heart defects researchDevelopmental Biology and Gene Regulation

Cited by 65

A systematic screen for genes expressed in definitive endoderm by Serial Analysis of Gene Expression (SAGE)

Hou, J., Charters, A. M., Lee, S. C., Zhao, Y., Wu, M. K., Jones, S. J., Marra, M. A., & Hoodless, P. A. (2007) · BMC Developmental Biology

Developmental Biology and Gene RegulationPluripotent Stem Cells Research

Cited by 56

Fetal liver development and implications for liver disease pathogenesis

Lotto, J., Stephan, T. L., & Hoodless, P. A. (2023) · Nature Reviews Gastroenterology & Hepatology

Liver physiology and pathologyDevelopmental Biology and Gene Regulation

Cited by 47

Large-scale production of SAGE libraries from microdissected tissues, flow-sorted cells, and cell lines

Khattra, J., Delaney, A. D., Zhao, Y., Siddiqui, A., Asano, J., McDonald, H., Pandoh, P., Dhalla, N., Prabhu, A.-L., Ma, K., et al. (2007) · Genome Research

Genomics and Phylogenetic StudiesGene expression and cancer classification

Cited by 40

SOX9 reprograms endothelial cells by altering the chromatin landscape

Fuglerud, B. M., Drissler, S., Lotto, J., Stephan, T. L., Thakur, A., Cullum, R., & Hoodless, P. A. (2022) · Nucleic Acids Research

Genomics and Chromatin DynamicsDevelopmental Biology and Gene Regulation

Cited by 35

YAP transcriptionally regulates ErbB2 to promote liver cell proliferation

Wang, E. Y., Cheng, J.-C., Thakur, A., Yi, Y., Tsai, S.-H., & Hoodless, P. A. (2018) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms

Hippo pathway signaling and YAP/TAZLiver physiology and pathology

Cited by 24

Signalling pathways and transcriptional regulators orchestrating liver development and cancer

Campbell, S. A., Stephan, T. L., Lotto, J., Cullum, R., Drissler, S., & Hoodless, P. A. (2021) · Development

Liver physiology and pathologyDevelopmental Biology and Gene Regulation

Cited by 22

Genome-wide microRNA and messenger RNA profiling in rodent liver development implicates mir302b and mir20a in repressing transforming growth factor-beta signaling

Wei, W., Hou, J., Alder, O., Ye, X., Lee, S., Cullum, R., Chu, A., Zhao, Y., Warner, S. M., Knight, D. A., et al. (2013) · Hepatology

MicroRNA in disease regulationDevelopmental Biology and Gene Regulation

Cited by 19

Cell diversity and plasticity during atrioventricular heart valve EMTs

Lotto, J., Cullum, R., Drissler, S., Arostegui, M., Garside, V. C., Fuglerud, B. M., Clement-Ranney, M., Thakur, A., Underhill, T. M., & Hoodless, P. A. (2023) · Nature Communications

Congenital heart defects researchDevelopmental Biology and Gene Regulation

Cited by 13

HNF4A guides the MLL4 complex to establish and maintain H3K4me1 at gene regulatory elements

Thakur, A., Park, K., Cullum, R., Fuglerud, B. M., Khoshnoodi, M., Drissler, S., Stephan, T. L., Lotto, J., Kim, D., Gonzalez, F. J., et al. (2024) · Communications Biology

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 10