Valencia, Alfonso

The structural coverage of the human proteome before and after AlphaFold

Porta-Pardo, E., Ruiz-Serra, V., Valentini, S., & Valencia, A. (2022) · PLOS Computational Biology

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 131

A structural biology community assessment of AlphaFold 2 applications

Akdel, M., Pires, D. E. V., Porta Pardo, E., Jänes, J., Zalevsky, A. O., Mészáros, B., Bryant, P., Good, L. L., Laskowski, R. A., Pozzati, G., et al. (2021) · bioRxiv (Cold Spring Harbor Laboratory)

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 122

Comparative proteomics reveals a significant bias toward alternative protein isoforms with conserved structure and function

Ezkurdia, I., del Pozo, A., Frankish, A., Rodriguez, J. M., Harrow, J., Ashman, K., Valencia, A., & Tress, M. L. (2012) · Molecular Biology and Evolution

Advanced Proteomics Techniques and ApplicationsRNA Research and Splicing

Cited by 89

Text Mining for Metabolic Pathways, Signaling Cascades, and Protein Networks

Hoffmann, R., Krallinger, M., Andres, E., Tamames, J., Blaschke, C., & Valencia, A. (2005) · Science's STKE

Biomedical Text Mining and OntologiesBioinformatics and Genomic Networks

Cited by 88

Life cycles of successful genes

Hoffmann, R., & Valencia, A. (2003) · Trends in Genetics

scientometrics and bibliometrics researchBioinformatics and Genomic Networks

Cited by 69

Genome-wide analysis of Pax8 binding provides new insights into thyroid functions

Ruiz-Llorente, S., de Pau, E. C. S., Sastre-Perona, A., Montero-Conde, C., Gómez-López, G., Fagin, J. A., Valencia, A., Pisano, D. G., & Santisteban, P. (2012) · BMC Genomics

Genomics and Chromatin DynamicsThyroid Disorders and Treatments

Cited by 51

Identification of a Mammalian Homologue of the Fungal Tom70 Mitochondrial Precursor Protein Import Receptor as a Thyroid Mitochondrial Precursor Protein Import Receptor as a Thyroid Hormone‐Regulated Gene in Specific Brain Regions

Alvarez‐Dolado, M., González‐Moreno, M., Valencia, A., Zenke, M., Bernal, J., & Muñoz, A. (1999) · Journal of Neurochemistry

Thyroid Disorders and TreatmentsMitochondrial Function and Pathology

Cited by 37

How to Design AI-Driven Clinical Trials in Nuclear Medicine

Delso, G., Cirillo, D., Kaggie, J. D., Valencia, A., Metser, U., & Veit-Haibach, P. (2021) · Seminars in Nuclear Medicine

Artificial Intelligence in Healthcare and EducationMedical Imaging Techniques and Applications

Cited by 36

Apolipoprotein E2 (Arg-136-->Cys), a variant of apolipoprotein E associated with late-onset dominance of type III hyperlipoproteinaemia

FEUSSNER, G., ALBANESE, M., MANN, W. A., VALENCIA, A., & SCHUSTER, H. (1996) · European Journal of Clinical Investigation

Lipid metabolism and disordersLipoproteins and Cardiovascular Health

Cited by 29

Unveiling new disease, pathway, and gene associations via multi-scale neural network

Gaudelet, T., Malod-Dognin, N., Sánchez-Valle, J., Pancaldi, V., Valencia, A., & Pržulj, N. (2020) · PLoS ONE

Bioinformatics and Genomic NetworksGene expression and cancer classification

Cited by 25

Risk of mortality among children, adolescents, and adults with autism spectrum disorder or attention deficit hyperactivity disorder and their first-degree relatives: a protocol for a systematic review and meta-analysis of observational studies.

Catalá-López, F., Hutton, B., Page, M. J., Ridao, M., Driver, J. A., Alonso-Arroyo, A., Forés-Martos, J., Macías Saint-Gerons, D., Vieta, E., Valencia, A., et al. (2017) · Systematic Reviews

Autism Spectrum Disorder ResearchDown syndrome and intellectual disability research

Cited by 11

Frustraevo: a web server to localize and quantify the conservation of local energetic frustration in protein families

Parra, R. G., Freiberger, M. I., Poley-Gil, M., Fernandez-Martin, M., Radusky, L. G., Ruiz-Serra, V., Wolynes, P. G., Ferreiro, D. U., & Valencia, A. (2024) · Nucleic Acids Research

Protein Structure and DynamicsRNA and protein synthesis mechanisms

Cited by 10

Frustraevo: A Web Server To Localize And Quantify The Conservation Of Local Energetic Frustration In Protein Families

Parra, R. G., Freiberger, M. I., Poley-Gil, M., Fernandez-Martin, M., Radusky, L. G., Wolynes, P. G., Ferreiro, D. U., & Valencia, A. (2023) · Nucleic Acids Research

Protein Structure and DynamicsRNA and protein synthesis mechanisms

Cited by 10

Three-dimensional structure of the LDL receptor-binding domain of the human apolipoprotein E2 (Arg136 → Cys) variant

Feussner, G., Albanese, M., & Valencia, A. (1996) · Atherosclerosis

Lipoproteins and Cardiovascular HealthLipid metabolism and disorders

Cited by 7

3Dmapper: A Command Line Tool For BioBank-scale Mapping Of Variants To Protein Structures

Ruiz-Serra, V., Valentini, S., Madroñero, S., Valencia, A., & Porta-Pardo, E. (2023) · Bioinformatics

Genomics and Rare DiseasesEnzyme Structure and Function

Cited by 0

3Dmapper: a command line tool for BioBank-scale mapping of variants to protein structures

Ruiz-Serra, V., Valentini, S., Madroñero, S., Valencia, A., & Porta-Pardo, E. (2024) · Bioinformatics

Genomics and Rare DiseasesEnzyme Structure and Function

Cited by 0

Airway organoids reveal patterns of influenza A tropism and adaptation in wildlife species

Tarrés-Freixas, F., Ceada, G., Català-Moll, F., Casadellà, M., Tolosa-Alarcón, S., Franco-Trepat, E., Boreika, R., Almagro-Delgado, V., Carmona, N., Estruch, J., et al. (2026) · Emerging Microbes & Infections

Influenza Virus Research StudiesVirology and Viral Diseases

Cited by 0