Deane, Charlotte M.

SAbDab: the structural antibody database

Dunbar, J., Krawczyk, K., Leem, J., Baker, T., Fuchs, A., Georges, G., Shi, J., & Deane, C. M. (2014) · Nucleic Acids Research

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CoV-AbDab: the coronavirus antibody database

Raybould, M. I. J., Kovaltsuk, A., Marks, C., & Deane, C. M. (2021) · Bioinformatics

SARS-CoV-2 and COVID-19 Researchvaccines and immunoinformatics approaches

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Five computational developability guidelines for therapeutic antibody profiling

Raybould, M. I. J., Marks, C., Krawczyk, K., Taddese, B., Nowak, J., Lewis, A. P., Bujotzek, A., Shi, J., & Deane, C. M. (2019) · Proceedings of the National Academy of Sciences

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Observed antibody space: a diverse database of cleaned, annotated, and translated unpaired and paired antibody sequences

Olsen, T. H., Boyles, F., & Deane, C. M. (2022) · Protein Science

Monoclonal and Polyclonal Antibodies Researchvaccines and immunoinformatics approaches

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Observed antibody space: a resource for data mining next-generation sequencing of antibody repertoires

Kovaltsuk, A., Leem, J., Kelm, S., Snowden, J., Deane, C. M., & Krawczyk, K. (2018) · The Journal of Immunology

Monoclonal and Polyclonal Antibodies ResearchT-cell and B-cell Immunology

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ABodyBuilder: automated antibody structure prediction with data-driven accuracy estimation

Leem, J., Dunbar, J., Georges, G., Shi, J., & Deane, C. M. (2016) · mAbs

Protein Structure and DynamicsMonoclonal and Polyclonal Antibodies Research

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Thera-SAbDab: the therapeutic structural antibody database

Raybould, M. I. J., Marks, C., Lewis, A. P., Shi, J., Bujotzek, A., Taddese, B., & Deane, C. M. (2020) · Nucleic Acids Research

Monoclonal and Polyclonal Antibodies ResearchEnzyme Structure and Function

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AbLang: an antibody language model for completing antibody sequences

Olsen, T. H., Moal, I. H., & Deane, C. M. (2022) · Bioinformatics Advances

Monoclonal and Polyclonal Antibodies ResearchMachine Learning in Bioinformatics

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Improving B-cell epitope prediction and its application to global antibody–antigen docking

Krawczyk, K., Liu, X., Baker, T., Shi, J., & Deane, C. M. (2014) · Bioinformatics

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FREAD revisited: accurate loop structure prediction using a database search algorithm

Choi, Y., & Deane, C. M. (2010) · Proteins Structure Function and Bioinformatics

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 161

ABlooper: Fast accurate antibody CDR loop structure prediction with accuracy estimation

Abanades, B., Georges, G., Bujotzek, A., & Deane, C. M. (2021) · Bioinformatics

Protein Structure and DynamicsMonoclonal and Polyclonal Antibodies Research

Cited by 157

ABlooper: fast accurate antibody CDR loop structure prediction with accuracy estimation

Abanades, B., Georges, G., Bujotzek, A., & Deane, C. M. (2022) · Bioinformatics

Protein Structure and DynamicsMonoclonal and Polyclonal Antibodies Research

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ABangle: characterising the VH-VL orientation in antibodies

Dunbar, J., Fuchs, A., Shi, J., & Deane, C. M. (2013) · Protein Engineering Design and Selection

Protein Structure and DynamicsMonoclonal and Polyclonal Antibodies Research

Cited by 125

Humanization of antibodies using a machine learning approach on large-scale repertoire data

Marks, C., Hummer, A. M., Chin, M., & Deane, C. M. (2021) · Bioinformatics

Monoclonal and Polyclonal Antibodies Researchvaccines and immunoinformatics approaches

Cited by 124

DLAB-deep learning methods for structure-based virtual screening of antibodies

Schneider, C., Buchanan, A., Taddese, B., & Deane, C. M. (2022) · Bioinformatics

Computational Drug Discovery Methodsvaccines and immunoinformatics approaches

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The H3 loop of antibodies shows unique structural characteristics

Regep, C., Georges, G., Shi, J., Popovic, B., & Deane, C. M. (2017) · Proteins Structure Function and Bioinformatics

Protein Structure and DynamicsMonoclonal and Polyclonal Antibodies Research

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Antibody i-Patch prediction of the antibody binding site improves rigid local antibody–antigen docking

Krawczyk, K., Baker, T., Shi, J., & Deane, C. M. (2013) · Protein Engineering Design and Selection

Protein Structure and Dynamicsvaccines and immunoinformatics approaches

Cited by 87

Current structure predictors are not learning the physics of protein folding

Outeiral, C., Nissley, D. A., & Deane, C. M. (2022) · Bioinformatics

Protein Structure and DynamicsRNA and protein synthesis mechanisms

Cited by 82

Sphinx: merging knowledge-based and ab initio approaches to improve protein loop prediction

Marks, C., Nowak, J., Klostermann, S., Georges, G., Dunbar, J., Shi, J., Kelm, S., & Deane, C. M. (2017) · Bioinformatics

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 56

Antibody H3 structure prediction

Marks, C., & Deane, C. M. (2017) · Computational and Structural Biotechnology Journal

Protein Structure and DynamicsMonoclonal and Polyclonal Antibodies Research

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Prediction of VH-VL domain orientation for antibody variable domain modeling

Bujotzek, A., Dunbar, J., Lipsmeier, F., Schäfer, W., Antes, I., Deane, C. M., & Georges, G. (2015) · Proteins Structure Function and Bioinformatics

Protein Structure and DynamicsMonoclonal and Polyclonal Antibodies Research

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Challenges in antibody structure prediction

Fernández-Quintero, M. L., Kokot, J., Waibl, F., Fischer, A.-L. M., Quoika, P. K., Deane, C. M., & Liedl, K. R. (2022) · mAbs

Protein Structure and DynamicsEnzyme Structure and Function

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Challenges in antibody structure prediction

Fernández-Quintero, M. L., Kokot, J., Waibl, F., Fischer, A.-L. M., Quoika, P. K., Deane, C. M., & Liedl, K. R. (2023) · mAbs

Protein Structure and DynamicsEnzyme Structure and Function

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Epitope profiling using computational structural modelling demonstrated on coronavirus-binding antibodies

Robinson, S. A., Raybould, M. I. J., Schneider, C., Wong, W. K., Marks, C., & Deane, C. M. (2021) · PLOS Computational Biology

vaccines and immunoinformatics approachesMonoclonal and Polyclonal Antibodies Research

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