Murrough, James W.

A Randomized Controlled Trial of Repeated Ketamine Administration for Chronic Posttraumatic Stress Disorder

Feder, A., Costi, S., Rutter, S. B., Collins, A. B., Govindarajulu, U., Jha, M. K., Horn, S. R., Kautz, M., Corniquel, M., Collins, K. A., et al. (2021) · American Journal of Psychiatry

Posttraumatic Stress Disorder ResearchTreatment of Major Depression

Cited by 246

Ketamine Safety and Tolerability in Clinical Trials for Treatment-Resistant Depression

Wan, L.-B., Levitch, C. F., Perez, A. M., Brallier, J. W., Iosifescu, D. V., Chang, L. C., Foulkes, A., Mathew, S. J., Charney, D. S., & Murrough, J. W. (2015) · The Journal of Clinical Psychiatry

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 231

A randomized proof-of-mechanism trial applying the ‘fast-fail’ approach to evaluating κ-opioid antagonism as a treatment for anhedonia

Krystal, A. D., Pizzagalli, D. A., Smoski, M., Mathew, S. J., Nurnberger, J., Lisanby, S. H., Iosifescu, D., Murrough, J. W., Yang, H., Weiner, R. D., et al. (2020) · Nature Medicine

Neuropeptides and Animal PhysiologyTreatment of Major Depression

Cited by 227

Ketamine for suicidal ideation in adults with psychiatric disorders: A systematic review and meta-analysis of treatment trials

Witt, K., Potts, J., Hubers, A., Grunebaum, M. F., Murrough, J. W., Loo, C., Cipriani, A., & Hawton, K. (2020) · Australian & New Zealand Journal of Psychiatry

Treatment of Major DepressionSuicide and Self-Harm Studies

Cited by 202

Peripheral immune-derived matrix metalloproteinase promotes stress susceptibility

Russo, S., Cathomas, F., Lin, H.-Y., Chan, K., Li, L., Durand-de Cuttoli, R., Parise, L., Aubry, A., Muhareb, S., Desland, F., et al. (2023) · Nature

Tryptophan and brain disordersStress Responses and Cortisol

Cited by 189

Circulating myeloid-derived MMP8 in stress susceptibility and depression

Cathomas, F., Lin, H.-Y., Chan, K. L., Li, L., Parise, L. F., Alvarez, J., Durand-de Cuttoli, R., Aubry, A. V., Muhareb, S., Desland, F., et al. (2024) · Nature

Tryptophan and brain disordersStress Responses and Cortisol

Cited by 189

Shared Neural Phenotypes for Mood and Anxiety Disorders: A Meta-analysis of 226 Task-Related Functional Imaging Studies

Janiri, D., Moser, D. A., Doucet, G. E., Luber, M. J., Rasgon, A., Lee, W. H., Murrough, J. W., Sani, G., Eickhoff, S. B., & Frangou, S. (2020) · JAMA Psychiatry

Anxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesNeural and Behavioral Psychology Studies

Cited by 173

Ketamine as a Novel Antidepressant: From Synapse to Behavior

Murrough, J. W. (2012) · Clinical Pharmacology & Therapeutics

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 172

KCNQ channel openers reverse depressive symptoms via an active resilience mechanism

Friedman, A. K., Juarez, B., Ku, S. M., Zhang, H., Calizo, R. C., Walsh, J. J., Chaudhury, D., Zhang, S., Hawkins, A., Dietz, D. M., et al. (2016) · Nature Communications

Treatment of Major DepressionNeurotransmitter Receptor Influence on Behavior

Cited by 172

Reduced global functional connectivity of the medial prefrontal cortex in major depressive disorder

Murrough, J. W., Abdallah, C. G., Anticevic, A., Collins, K. A., Geha, P., Averill, L. A., Schwartz, J., DeWilde, K. E., Averill, C., Jia‐Wei Yang, G., et al. (2016) · Human Brain Mapping

Functional Brain Connectivity StudiesTreatment of Major Depression

Cited by 153

Acetyl- l -carnitine deficiency in patients with major depressive disorder

Nasca, C., Bigio, B., Lee, F. S., Young, S. P., Kautz, M. M., Albright, A., Beasley, J., Millington, D. S., Mathé, A. A., Kocsis, J. H., et al. (2018) · Proceedings of the National Academy of Sciences

Treatment of Major DepressionTryptophan and brain disorders

Cited by 152

Neurocognitive Effects of Ketamine and Association with Antidepressant Response in Individuals with Treatment-Resistant Depression: A Randomized Controlled Trial

Murrough, J. W., Burdick, K. E., Levitch, C. F., Perez, A. M., Brallier, J. W., Chang, L. C., Foulkes, A., Charney, D. S., Mathew, S. J., & Iosifescu, D. V. (2015) · Neuropsychopharmacology

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 142

Regulation of neural responses to emotion perception by ketamine in individuals with treatment-resistant major depressive disorder

Murrough, J. W., Collins, K. A., Fields, J., DeWilde, K. E., Phillips, M. L., Mathew, S. J., Wong, E., Tang, C. Y., Charney, D. S., & Iosifescu, D. V. (2015) · Translational Psychiatry

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 109

Efficacy of Esketamine Augmentation in Major Depressive Disorder: A Meta-Analysis

Papakostas, G. I., Salloum, N. C., Hock, R. S., Jha, M. K., Murrough, J. W., Mathew, S. J., Iosifescu, D. V., & Fava, M. (2020) · The Journal of Clinical Psychiatry

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 108

Ketamine normalizes subgenual cingulate cortex hyper-activity in depression

Morris, L. S., Costi, S., Tan, A., Stern, E. R., Charney, D. S., & Murrough, J. W. (2020) · Neuropsychopharmacology

Treatment of Major DepressionTranscranial Magnetic Stimulation Studies

Cited by 104

Reduced amygdala serotonin transporter binding in posttraumatic stress disorder

Murrough, J. W., Huang, Y., Hu, J., Henry, S., Williams, W., Gallezot, J.-D., Bailey, C. R., Krystal, J. H., Carson, R. E., & Neumeister, A. (2011) · Biological Psychiatry

Posttraumatic Stress Disorder ResearchNeurotransmitter Receptor Influence on Behavior

Cited by 92

Peripheral immune cell reactivity and neural response to reward in patients with depression and anhedonia

Costi, S., Morris, L. S., Collins, A., Fernandez, N. F., Patel, M., Xie, H., Kim-Schulze, S., Stern, E. R., Collins, K. A., Cathomas, F., et al. (2021) · Translational Psychiatry

Tryptophan and brain disordersStress Responses and Cortisol

Cited by 87

International pooled patient-level meta-analysis of ketamine infusion for depression: In search of clinical moderators

Price, R. B., Kissel, N., Baumeister, A., Rohac, R., Woody, M. L., Ballard, E. D., Zarate, C. A., Deakin, W., Abdallah, C. G., Feder, A., et al. (2022) · Molecular Psychiatry

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 82

A randomized dose-ranging study of neuropeptide Y in patients with posttraumatic stress disorder

Sayed, S., Van Dam, N. T., Horn, S. R., Kautz, M. M., Parides, M., Costi, S., Collins, K. A., Iacoviello, B., Iosifescu, D. V., Mathé, A. A., et al. (2018) · International Journal of Neuropsychopharmacology

Posttraumatic Stress Disorder ResearchNeuropeptides and Animal Physiology

Cited by 79

Ketamine-induced changes in plasma brain-derived neurotrophic factor (BDNF) levels are associated with the resting-state functional connectivity of the prefrontal cortex

Woelfer, M., Li, M., Colic, L., Liebe, T., Di, X., Biswal, B., Murrough, J., Lessmann, V., Brigadski, T., & Walter, M. (2020) · The World Journal of Biological Psychiatry

Treatment of Major DepressionFunctional Brain Connectivity Studies

Cited by 64

Dextromethorphan/quinidine pharmacotherapy in patients with treatment resistant depression: A proof of concept clinical trial

Murrough, J. W., Stade, E., Sayed, S., Ahle, G., Kiraly, D. D., Welch, A., Collins, K. A., Soleimani, L., Iosifescu, D. V., & Charney, D. S. (2017) · Journal of Affective Disorders

Treatment of Major DepressionPharmacological Receptor Mechanisms and Effects

Cited by 62

Lithium continuation therapy following ketamine in patients with treatment resistant unipolar depression: A randomized controlled trial

Costi, S., Soleimani, L., Glasgow, A., Brallier, J., Spivack, J., Schwartz, J., Levitch, C. F., Richards, S., Hoch, M., Stade, E. C., et al. (2019) · Neuropsychopharmacology

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 56

A randomized, controlled pilot trial of the Emotional Faces Memory Task: a digital therapeutic for depression

Iacoviello, B. M., Murrough, J. W., Hoch, M. M., Huryk, K. M., Collins, K. A., Cutter, G. R., Iosifescu, D. V., & Charney, D. S. (2018) · npj Digital Medicine

Digital Mental Health InterventionsAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Cited by 40

High-dose ondansetron reduces activation of interoceptive and sensorimotor brain regions

Stern, E. R., Shahab, R., Grimaldi, S. J., Leibu, E., Murrough, J. W., Fleysher, L., Parides, M. K., Coffey, B. J., Burdick, K. E., & Goodman, W. K. (2019) · Neuropsychopharmacology

Psychosomatic Disorders and Their TreatmentsGastrointestinal motility and disorders

Cited by 27