Goronzy, Jörg J.

Defective proliferative capacity and accelerated telomeric loss of hematopoietic progenitor cells in rheumatoid arthritis.

Colmegna, I., Diaz‐Borjon, A., Fujii, H., Schaefer, L., Goronzy, J. J., & Weyand, C. M. (2008) · Arthritis & Rheumatism

Rheumatoid Arthritis Research and TherapiesHematopoietic Stem Cell Transplantation

Cited by 108

Signal inhibition by the dual-specific phosphatase 4 impairs T cell-dependent B-cell responses with age

Yu, M., Li, G., Lee, W.-W., Yuan, M., Cui, D., Weyand, C. M., & Goronzy, J. J. (2012) · Proceedings of the National Academy of Sciences

T-cell and B-cell ImmunologyProtein Tyrosine Phosphatases

Cited by 102

Chronic inflammation and aging: DNA damage tips the balance

Cavanagh, M. M., Weyand, C. M., & Goronzy, J. J. (2012) · Current Opinion in Immunology

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 99

Peripheral selection rather than thymic involution explains sudden contraction in naive CD4 T-cell diversity with age

Johnson, P. L. F., Yates, A. J., Goronzy, J. J., & Antia, R. (2012) · Proceedings of the National Academy of Sciences

T-cell and B-cell ImmunologyEvolution and Genetic Dynamics

Cited by 94

DNA-dependent protein kinase catalytic subunit mediates T-cell loss in rheumatoid arthritis.

Shao, L., Goronzy, J. J., & Weyand, C. M. (2010) · EMBO Molecular Medicine

DNA Repair MechanismsRheumatoid Arthritis Research and Therapies

Cited by 69

Epigenetics of T cell aging

Goronzy, J. J., Hu, B., Kim, C., Jadhav, R. R., & Weyand, C. M. (2018) · Journal of Leukocyte Biology

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 60

Tissue trafficking patterns of effector memory CD4 T cells in rheumatoid arthritis.

Zhang, X., Nakajima, T., Goronzy, J. J., & Weyand, C. M. (2005) · Arthritis & Rheumatism

Rheumatoid Arthritis Research and TherapiesT-cell and B-cell Immunology

Cited by 56

Promoter choice and translational repression determine cell type-specific cell surface density of the inhibitory receptor CD85j expressed on different hematopoietic lineages

Lamar, D. L., Weyand, C. M., & Goronzy, J. J. (2010) · Blood

Immune Cell Function and InteractionT-cell and B-cell Immunology

Cited by 45

High-throughput sequencing insights into T-cell receptor repertoire diversity in aging

Goronzy, J. J., Qi, Q., Olshen, R. A., & Weyand, C. M. (2015) · Genome Medicine

T-cell and B-cell ImmunologySingle-cell and spatial transcriptomics

Cited by 36

A Mitochondrial Checkpoint in Autoimmune Disease

Weyand, C. M., & Goronzy, J. J. (2018) · Cell Metabolism

T-cell and B-cell ImmunologyMitochondrial Function and Pathology

Cited by 12