Michalopoulos, George K.

Liver Regeneration

Michalopoulos, G. K., & DeFrances, M. C. (1997) · Science

Liver physiology and pathologyOrgan Transplantation Techniques and Outcomes

Cited by 2,828

Liver regeneration

Michalopoulos, G. K. (2007) · Journal of Cellular Physiology

Liver physiology and pathologyOrgan Transplantation Techniques and Outcomes

Cited by 1,384

Liver regeneration: biological and pathological mechanisms and implications

Michalopoulos, G. K., & Bhushan, B. (2021) · Nature Reviews Gastroenterology & Hepatology

Liver physiology and pathologyTissue Engineering and Regenerative Medicine

Cited by 998

Liver Regeneration after Partial Hepatectomy

Michalopoulos, G. K. (2010) · The American Journal of Pathology

Liver physiology and pathologyTissue Engineering and Regenerative Medicine

Cited by 713

Hepatostat: Liver regeneration and normal liver tissue maintenance

Michalopoulos, G. K. (2017) · Hepatology

Liver physiology and pathologyTissue Engineering and Regenerative Medicine

Cited by 444

Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations

Affo, S., Nair, A., Brundu, F., Ravichandra, A., Bhattacharjee, S., Matsuda, M., Chin, L., Filliol, A., Wen, W., Song, X., et al. (2021) · Cancer Cell

Cholangiocarcinoma and Gallbladder Cancer StudiesLiver physiology and pathology

Cited by 416

Conditional Deletion of β-Catenin Reveals Its Role in Liver Growth and Regeneration

Tan, X., Behari, J., Cieply, B., Michalopoulos, G. K., & Monga, S. P. S. (2006) · Gastroenterology

Liver physiology and pathologyWnt/β-catenin signaling in development and cancer

Cited by 361

Cross-talk between Epidermal Growth Factor Receptor and c-Met Signal Pathways in Transformed Cells*

Jo, M., Stolz, D. B., Esplen, J. E., Dorko, K., Michalopoulos, G. K., & Strom, S. C. (2000) · Journal of Biological Chemistry

HER2/EGFR in Cancer ResearchLiver physiology and pathology

Cited by 347

Transdifferentiation of rat hepatocytes into biliary cells after bile duct ligation and toxic biliary injury†

Michalopoulos, G. K., Barua, L., & Bowen, W. C. (2005) · Hepatology

Liver physiology and pathologyDrug-Induced Hepatotoxicity and Protection

Cited by 319

Changes in Wnt/β–Catenin Pathway During Regulated Growth in Rat Liver Regeneration

Monga, S. P. S., Pediaditakis, P., Mule, K., Stolz, D. B., & Michalopoulos, G. K. (2001) · Hepatology

Wnt/β-catenin signaling in development and cancerLiver physiology and pathology

Cited by 292

A Mechanism of Cell Survival

Wang, X., DeFrances, M. C., Dai, Y., Pediaditakis, P., Johnson, C., Bell, A., Michalopoulos, G. K., & Zarnegar, R. (2002) · Molecular Cell

Cell death mechanisms and regulationLiver physiology and pathology

Cited by 225

β-Catenin deletion in hepatoblasts disrupts hepatic morphogenesis and survival during mouse development

Tan, X., Yuan, Y., Zeng, G., Apte, U., Thompson, M. D., Cieply, B., Stolz, D. B., Michalopoulos, G. K., Kaestner, K. H., & Monga, S. P. S. (2008) · Hepatology

Liver physiology and pathologyWnt/β-catenin signaling in development and cancer

Cited by 202

Synthesis of IL-6 by Hepatocytes Is a Normal Response to Common Hepatic Stimuli

Norris, C. A., He, M., Kang, L.-I., Ding, M. Q., Radder, J. E., Haynes, M. M., Yang, Y., Paranjpe, S., Bowen, W. C., Orr, A., et al. (2014) · PLoS ONE

Cytokine Signaling Pathways and InteractionsLiver physiology and pathology

Cited by 132

Hepatocyte Growth Factor Exerts Its Anti-Inflammatory Action by Disrupting Nuclear Factor-κB Signaling

Giannopoulou, M., Dai, C., Tan, X., Wen, X., Michalopoulos, G. K., & Liu, Y. (2008) · The American Journal of Pathology

NF-κB Signaling PathwaysLiver physiology and pathology

Cited by 126

Combined systemic elimination of MET and epidermal growth factor receptor signaling completely abolishes liver regeneration and leads to liver decompensation

Paranjpe, S., Bowen, W. C., Mars, W. M., Orr, A., Haynes, M. M., DeFrances, M. C., Liu, S., Tseng, G. C., Tsagianni, A., & Michalopoulos, G. K. (2016) · Hepatology

Liver physiology and pathologyOrgan Transplantation Techniques and Outcomes

Cited by 115

Liver stem cells: experimental findings and implications for human liver disease

Michalopoulos, G. K., & Khan, Z. (2015) · Gastroenterology

Liver physiology and pathologyMesenchymal stem cell research

Cited by 109

Cell cycle effects resulting from inhibition of hepatocyte growth factor and its receptor c-Met in regenerating rat livers by RNA interference

Paranjpe, S., Bowen, W. C., Bell, A. W., Nejak-Bowen, K., Luo, J.-H., & Michalopoulos, G. K. (2007) · Hepatology

Liver physiology and pathologyHepatocellular Carcinoma Treatment and Prognosis

Cited by 100

Expression of specific hepatocyte and cholangiocyte transcription factors in human liver disease and embryonic development

Limaye, P. B., Alarcón, G., Walls, A. L., Nalesnik, M. A., Michalopoulos, G. K., Demetris, A. J., & Ochoa, E. R. (2008) · Laboratory Investigation

Liver physiology and pathologyLiver Diseases and Immunity

Cited by 94

Suppression of Liver Regeneration and Hepatocyte Proliferation in Hepatocyte-Targeted Glypican 3 Transgenic Mice†

Liu, B., Bell, A. W., Paranjpe, S., Bowen, W. C., Khillan, J. S., Luo, J.-H., Mars, W. M., & Michalopoulos, G. K. (2010) · Hepatology

Liver physiology and pathologyProteoglycans and glycosaminoglycans research

Cited by 77

Role of epidermal growth factor receptor in liver injury and lipid metabolism: Emerging new roles for an old receptor

Bhushan, B., & Michalopoulos, G. K. (2020) · Chemico-Biological Interactions

Liver physiology and pathologyDrug-Induced Hepatotoxicity and Protection

Cited by 66

TCPOBOP‐Induced Hepatomegaly and Hepatocyte Proliferation are Attenuated by Combined Disruption of MET and EGFR Signaling

Bhushan, B., Stoops, J. W., Mars, W. M., Orr, A., Bowen, W. C., Paranjpe, S., & Michalopoulos, G. K. (2019) · Hepatology

Liver physiology and pathologyDrug-Induced Hepatotoxicity and Protection

Cited by 49

The liver is a peculiar organ when it comes to stem cells

Michalopoulos, G. K. (2014) · The American Journal of Pathology

Liver physiology and pathologyMesenchymal stem cell research

Cited by 44

Combined Systemic Disruption of MET and Epidermal Growth Factor Receptor Signaling Causes Liver Failure in Normal Mice

Tsagianni, A., Mars, W. M., Bhushan, B., Bowen, W. C., Orr, A., Stoops, J., Paranjpe, S., Tseng, G. C., Liu, S., & Michalopoulos, G. K. (2018) · The American Journal of Pathology

Liver physiology and pathologyOrgan Transplantation Techniques and Outcomes

Cited by 29

Yes-associated protein is crucial for constitutive androstane receptor-driven hepatocyte proliferation but not for induction of drug metabolism genes in mice

Bhushan, B., Molina, L., Koral, K., Stoops, J. W., Mars, W. M., Banerjee, S., Orr, A., Paranjpe, S., Monga, S. P., Locker, J., et al. (2021) · Hepatology

Hippo pathway signaling and YAP/TAZLiver physiology and pathology

Cited by 20