Choudhary, Jyoti S.

Expanded encyclopaedias of DNA elements in the human and mouse genomes

The ENCODE Project Consortium, Abascal, F., Acosta, R., Addleman, N. J., Adrian, J., Afzal, V., Ai, R., Aken, B., Akiyama, J. A., Jammal, O. A., et al. (2020) · Nature

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

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A polygenic burden of rare disruptive mutations in schizophrenia

Purcell, S. M., Moran, J. L., Fromer, M., Ruderfer, D., Solovieff, N., Roussos, P., O’Dushlaine, C., Chambert, K., Bergen, S. E., Kähler, A., et al. (2014) · Nature

Schizophrenia research and treatmentGenetic Associations and Epidemiology

Cited by 1,385

GENCODE 2021

Frankish, A., Diekhans, M., Jungreis, I., Lagarde, J., Loveland, J. E., Mudge, J. M., Sisu, C., Wright, J. C., Armstrong, J., Barnes, I., et al. (2021) · Nucleic Acids Research

Genomics and Phylogenetic StudiesRNA Research and Splicing

Cited by 1,334

Proteomic analysis of NMDA receptor–adhesion protein signaling complexes

Husi, H., Ward, M. A., Choudhary, J. S., Blackstock, W. P., & Grant, S. G. N. (2000) · Nature Neuroscience

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 1,194

De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia

Kirov, G., Pocklington, A. J., Holmans, P., Ivanov, D., Ikeda, M., Ruderfer, D., Moran, J., Chambert, K., Toncheva, D., Georgieva, L., et al. (2012) · Molecular Psychiatry

Genomic variations and chromosomal abnormalitiesSchizophrenia research and treatment

Cited by 844

Characterization of the proteome, diseases and evolution of the human postsynaptic density

Bayés, À., van de Lagemaat, L. N., Collins, M. O., Croning, M. D. R., Whittle, I. R., Choudhary, J. S., & Grant, S. G. N. (2011) · Nature Neuroscience

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 499

Proteogenomics of Non-smoking Lung Cancer in East Asia Delineates Molecular Signatures of Pathogenesis and Progression

Chen, Y.-J., Roumeliotis, T. I., Chang, Y.-H., Chen, C.-T., Han, C.-L., Lin, M.-H., Chen, H.-W., Chang, G.-C., Chang, Y.-L., Wu, C.-T., et al. (2020) · Cell

Lung Cancer Treatments and MutationsCancer Genomics and Diagnostics

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An Expanded Oct4 Interaction Network: Implications for Stem Cell Biology, Development, and Disease

Pardo, M., Lang, B., Yu, L., Prosser, H., Bradley, A., Babu, M. M., & Choudhary, J. (2010) · Cell Stem Cell

Pluripotent Stem Cells ResearchDevelopmental Biology and Gene Regulation

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Proteomic Analysis of in Vivo Phosphorylated Synaptic Proteins

Collins, M. O., Yu, L., Coba, M. P., Husi, H., Campuzano, I., Blackstock, W. P., Choudhary, J. S., & Grant, S. G. N. (2005) · Journal of Biological Chemistry

Advanced Proteomics Techniques and ApplicationsNeuroscience and Neuropharmacology Research

Cited by 320

Single-cell transcriptomics identifies an effectorness gradient shaping the response of CD4+ T cells to cytokines

Cano-Gamez, K., Soskic, B., Roumeliotis, T. I., So, E., Smyth, D. J., Baldrighi, M., Willé, D., Nakic, N., Esparza-Gordillo, J., Larminie, C. G. C., et al. (2020) · Nature Communications

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

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Comparative Study of Human and Mouse Postsynaptic Proteomes Finds High Compositional Conservation and Abundance Differences for Key Synaptic Proteins

Bayés, À., Collins, M. O., Croning, M. D. R., van de Lagemaat, L. N., Choudhary, J. S., & Grant, S. G. N. (2012) · PLoS ONE

Neuroscience and Neuropharmacology ResearchAdvanced Proteomics Techniques and Applications

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Shotgun proteomics aids discovery of novel protein-coding genes, alternative splicing, and “resurrected” pseudogenes in the mouse genome

Brosch, M., Saunders, G. I., Frankish, A., Collins, M. O., Yu, L., Wright, J., Verstraten, R., Adams, D. J., Harrow, J., Choudhary, J. S., et al. (2011) · Genome Research

Advanced Proteomics Techniques and ApplicationsGenomics and Phylogenetic Studies

Cited by 130

SynGAP isoforms exert opposing effects on synaptic strength

McMahon, A. C., Barnett, M. W., O'Leary, T. S., Stoney, P. N., Collins, M. O., Papadia, S., Choudhary, J. S., Komiyama, N. H., Grant, S. G. N., Hardingham, G. E., et al. (2012) · Nature Communications

Neuroscience and Neuropharmacology ResearchRNA Research and Splicing

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Discovery of high-confidence human protein-coding genes and exons by whole-genome PhyloCSF helps elucidate 118 GWAS loci

Mudge, J. M., Jungreis, I., Hunt, T., Gonzalez, J. M., Wright, J. C., Kay, M., Davidson, C., Fitzgerald, S., Seal, R., Tweedie, S., et al. (2019) · Genome Research

Genomics and Phylogenetic StudiesGenomics and Rare Diseases

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Characterization of two distinct Nucleosome Remodeling and Deacetylase (NuRD) complex assemblies in embryonic stem cells

Bode, D., Yu, L., Tate, P., Pardo, M., & Choudhary, J. (2016) · Molecular & Cellular Proteomics

Pluripotent Stem Cells ResearchGenomics and Chromatin Dynamics

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Mechanism of assembly, activation and lysine selection by the SIN3B histone deacetylase complex

Wan, M. S. M., Muhammad, R., Koliopoulos, M. G., Roumeliotis, T. I., Choudhary, J. S., & Alfieri, C. (2023) · Nature Communications

Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics

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Mechanism of assembly, activation and lysine selection by the SIN3B histone deacetylase complex

Wan, M. S. M., Muhammad, R., Koliopoulos, M. G., Roumeliotis, T. I., Choudhary, J. S., & Alfieri, C. (2023) · Nature Communications

Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics

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EROS is a selective chaperone regulating the phagocyte NADPH oxidase and purinergic signalling

Randzavola, L. O., Mortimer, P. M., Garside, E., Dufficy, E. R., Schejtman, A., Roumelioti, G., Yu, L., Pardo, M., Spirohn, K., Tolley, C., et al. (2022) · eLife

Neutrophil, Myeloperoxidase and Oxidative MechanismsImmunodeficiency and Autoimmune Disorders

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EROS is a selective chaperone regulating the phagocyte NADPH oxidase and purinergic signalling

Randzavola, L. O., Mortimer, P. M., Garside, E., Dufficy, E. R., Schejtman, A., Roumelioti, G., Yu, L., Pardo, M., Spirohn, K., Tolley, C., et al. (2021) · eLife

Neutrophil, Myeloperoxidase and Oxidative MechanismsImmunodeficiency and Autoimmune Disorders

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Systematic screens for fertility genes essential for malaria parasite transmission reveal conserved aspects of sex in a divergent eukaryote

Sayers, C., Pandey, V., Balakrishnan, A., Michie, K., Svedberg, D., Hunziker, M., Pardo, M., Choudhary, J., Berntsson, R., & Billker, O. (2024) · Cell Systems

Malaria Research and ControlMicrotubule and mitosis dynamics

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Precision Medicine in Pancreatic Disease—Knowledge Gaps and Research Opportunities: Summary of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop

Lowe, M. E., Andersen, D. K., Caprioli, R. M., Choudhary, J., Cruz-Monserrate, Z., Dasyam, A. K., Forsmark, C. E., Gorelick, F. S., Gray, J. W., Haupt, M., et al. (2019) · Pancreas

Pancreatitis Pathology and TreatmentPancreatic and Hepatic Oncology Research

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