Mao, Zhiyong

SIRT6 Promotes DNA Repair Under Stress by Activating PARP1

Mao, Z., Hine, C., Tian, X., Van Meter, M., Au, M., Vaidya, A., Seluanov, A., & Gorbunova, V. (2011) · Science

DNA Repair MechanismsSirtuins and Resveratrol in Medicine

Cited by 867

Changes in DNA repair during aging

Gorbunova, V., Seluanov, A., Mao, Z., & Hine, C. (2007) · Nucleic Acids Research

DNA Repair MechanismsGenetics, Aging, and Longevity in Model Organisms

Cited by 405

SIRT6 is responsible for more efficient DNA double-strand break repair in long-lived species

Tian, X., Firsanov, D., Zhang, Z., Cheng, Y., Luo, L., Tombline, G., Tan, R., Simon, M., Henderson, S., Steffan, J., et al. (2019) · Cell

Genetics, Aging, and Longevity in Model OrganismsDNA Repair Mechanisms

Cited by 353

Sirtuin 6 (SIRT6) rescues the decline of homologous recombination repair during replicative senescence

Mao, Z., Tian, X., Van Meter, M., Ke, Z., Gorbunova, V., & Seluanov, A. (2012) · Proceedings of the National Academy of Sciences

DNA Repair MechanismsTelomeres, Telomerase, and Senescence

Cited by 176

Replicatively senescent cells are arrested in G1 and G2 phases

Mao, Z., Ke, Z., Gorbunova, V., & Seluanov, A. (2012) · Aging

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 128

Repairing split ends: SIRT6, mono-ADP ribosylation and DNA repair

Van Meter, M., Mao, Z., Gorbunova, V., & Seluanov, A. (2011) · Aging

Sirtuins and Resveratrol in MedicineDNA Repair Mechanisms

Cited by 80

Loss of the receptors ER, PR and HER2 promotes USP15-dependent stabilization of PARP1 in triple-negative breast cancer

Sun, X., Tang, H., Chen, Y., Chen, Z., Hu, Z., Cui, Z., Tao, Y., Yuan, J., Fu, Y., Zhuang, Z., et al. (2023) · Nature Cancer

PARP inhibition in cancer therapyUbiquitin and proteasome pathways

Cited by 66

Single senescent cell sequencing reveals heterogeneity in senescent cells induced by telomere erosion

Tang, H., Geng, A., Zhang, T., Wang, C., Jiang, Y., & Mao, Z. (2019) · Protein & Cell

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 47