Wetsel, William C.

Role of Serotonin in the Paradoxical Calming Effect of Psychostimulants on Hyperactivity

Gainetdinov, R. R., Wetsel, W. C., Jones, S. R., Levin, E. D., Jaber, M., & Caron, M. G. (1999) · Science

Attention Deficit Hyperactivity DisorderNeurotransmitter Receptor Influence on Behavior

Cited by 885

Cortico-striatal synaptic defects and OCD-like behaviours in Sapap3-mutant mice

Welch, J. M., Lu, J., Rodriguiz, R. M., Trotta, N. C., Peca, J., Ding, J.-D., Feliciano, C., Chen, M., Adams, J. P., Luo, J., et al. (2007) · Nature

Obsessive-Compulsive Spectrum DisordersNeuroscience and Neuropharmacology Research

Cited by 852

Automated design of ligands to polypharmacological profiles

Besnard, J., Ruda, G. F., Setola, V., Abecassis, K., Rodriguiz, R. M., Huang, X.-P., Norval, S., Sassano, M. F., Shin, A. I., Webster, L. A., et al. (2012) · Nature

Computational Drug Discovery MethodsCholinesterase and Neurodegenerative Diseases

Cited by 832

Synaptic dysfunction and abnormal behaviors in mice lacking major isoforms of Shank3

Wang, X., McCoy, P. A., Rodriguiz, R. M., Pan, Y., Je, H. S., Roberts, A. C., Kim, C. J., Berrios, J., Colvin, J. S., Bousquet-Moore, D., et al. (2011) · Human Molecular Genetics

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 537

Targeted disruption of the mouse gene encoding steroidogenic acute regulatory protein provides insights into congenital lipoid adrenal hyperplasia

Caron, K. M., Soo, S.-C., Wetsel, W. C., Stocco, D. M., Clark, B. J., & Parker, K. L. (1997) · Proceedings of the National Academy of Sciences

Adrenal Hormones and DisordersSexual Differentiation and Disorders

Cited by 449

Role of GSK3β in behavioral abnormalities induced by serotonin deficiency

Beaulieu, J.-M., Zhang, X., Rodriguiz, R. M., Sotnikova, T. D., Cools, M. J., Wetsel, W. C., Gainetdinov, R. R., & Caron, M. G. (2008) · Proceedings of the National Academy of Sciences

Neurotransmitter Receptor Influence on BehaviorTreatment of Major Depression

Cited by 368

Genome-Wide Activity-Dependent MeCP2 Phosphorylation Regulates Nervous System Development and Function

Cohen, S., Gabel, H. W., Hemberg, M., Hutchinson, A. N., Sadacca, L. A., Ebert, D. H., Harmin, D. A., Greenberg, R. S., Verdine, V. K., Zhou, Z., et al. (2011) · Neuron

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 298

Mice Deficient for the Vesicular Acetylcholine Transporter Are Myasthenic and Have Deficits in Object and Social Recognition

Prado, V. F., Martins-Silva, C., de Castro, B. M., Lima, R. F., Barros, D. M., Amaral, E., Ramsey, A. J., Sotnikova, T. D., Ramirez, M. R., Kim, H.-G., et al. (2006) · Neuron

Neuroscience and Neuropharmacology ResearchMyasthenia Gravis and Thymoma

Cited by 246

Cocaine Increases Dopamine Release by Mobilization of a Synapsin-Dependent Reserve Pool

Venton, B. J., Seipel, A. T., Phillips, P. E. M., Wetsel, W. C., Gitler, D., Greengard, P., Augustine, G. J., & Wightman, R. M. (2006) · The Journal of Neuroscience

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 246

Psychedelic-inspired drug discovery using an engineered biosensor

Dong, C., Ly, C., Dunlap, L. E., Vargas, M. V., Sun, J., Hwang, I.-W., Azinfar, A., Oh, W. C., Wetsel, W. C., Olson, D. E., et al. (2021) · Cell

Psychedelics and Drug StudiesReceptor Mechanisms and Signaling

Cited by 213

Transient Inhibition of TrkB Kinase after Status Epilepticus Prevents Development of Temporal Lobe Epilepsy

Liu, G., Gu, B., He, X.-P., Joshi, R. B., Wackerle, H. D., Rodriguiz, R. M., Wetsel, W. C., & McNamara, J. O. (2013) · Neuron

Epilepsy research and treatmentNeuroscience and Neuropharmacology Research

Cited by 210

MeCP2 in the nucleus accumbens contributes to neural and behavioral responses to psychostimulants

Deng, J. V., Rodriguiz, R. M., Hutchinson, A. N., Kim, I.-H., Wetsel, W. C., & West, A. E. (2010) · Nature Neuroscience

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 206

Anterior pituitary hypoplasia and dwarfism in mice lacking the dopamine transporter

Bossé, R., Fumagalli, F., Jaber, M., Giros, B., Gainetdinov, R. R., Wetsel, W. C., Missale, C., & Caron, M. G. (1997) · Neuron

Hypothalamic control of reproductive hormonesGrowth Hormone and Insulin-like Growth Factors

Cited by 203

Modulation of neuroinflammation and memory dysfunction using percutaneous vagus nerve stimulation in mice

Huffman, W. J., Subramaniyan, S., Rodriguiz, R. M., Wetsel, W. C., Grill, W. M., & Terrando, N. (2019) · Brain Stimulation

Vagus Nerve Stimulation ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 181

Disruption of Arp2/3 Results in Asymmetric Structural Plasticity of Dendritic Spines and Progressive Synaptic and Behavioral Abnormalities

Kim, I. H., Racz, B., Wang, H., Burianek, L., Weinberg, R., Yasuda, R., Wetsel, W. C., & Soderling, S. H. (2013) · The Journal of Neuroscience

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 172

Abi2-Deficient Mice Exhibit Defective Cell Migration, Aberrant Dendritic Spine Morphogenesis, and Deficits in Learning and Memory

Grove, M., Demyanenko, G., Echarri, A., Zipfel, P. A., Quiroz, M. E., Rodriguiz, R. M., Playford, M., Martensen, S. A., Robinson, M. R., Wetsel, W. C., et al. (2004) · Molecular and Cellular Biology

Cellular Mechanics and InteractionsAxon Guidance and Neuronal Signaling

Cited by 136

Spine pruning drives antipsychotic-sensitive locomotion via circuit control of striatal dopamine

Kim, I. H., Rossi, M. A., Aryal, D. K., Racz, B., Kim, N., Uezu, A., Wang, F., Wetsel, W. C., Weinberg, R. J., Yin, H., et al. (2015) · Nature Neuroscience

Neuroscience and Neuropharmacology ResearchSchizophrenia research and treatment

Cited by 127

Differential psychostimulant-induced activation of neural circuits in dopamine transporter knockout and wild type mice

Trinh, J. V., Nehrenberg, D. L., Jacobsen, J. P. R., Caron, M. G., & Wetsel, W. C. (2003) · Neuroscience

Neurotransmitter Receptor Influence on BehaviorAttention Deficit Hyperactivity Disorder

Cited by 113

ANK2 autism mutation targeting giant ankyrin-B promotes axon branching and ectopic connectivity

Yang, R., Walder-Christensen, K. K., Kim, N., Wu, D., Lorenzo, D. N., Badea, A., Jiang, Y.-H., Yin, H. H., Wetsel, W. C., & Bennett, V. (2019) · Proceedings of the National Academy of Sciences

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders

Cited by 99

Increased Metabotropic Glutamate Receptor 5 Signaling Underlies Obsessive-Compulsive Disorder-like Behavioral and Striatal Circuit Abnormalities in Mice

Ade, K. K., Wan, Y., Hamann, H. C., O’Hare, J. K., Guo, W., Quian, A., Kumar, S., Bhagat, S., Rodriguiz, R. M., Wetsel, W. C., et al. (2016) · Biological Psychiatry

Obsessive-Compulsive Spectrum DisordersNeuroscience and Neuropharmacology Research

Cited by 84

Kctd13-deficient mice display short-term memory impairment and sex-dependent genetic interactions

Arbogast, T., Razaz, P., Ellegood, J., McKinstry, S. U., Erdin, S., Currall, B., Aneichyk, T., Lerch, J. P., Qiu, L. R., Rodriguiz, R. M., et al. (2019) · Human Molecular Genetics

Genomic variations and chromosomal abnormalitiesGenetics and Neurodevelopmental Disorders

Cited by 52

The fornix provides multiple biomarkers to characterize circuit disruption in a mouse model of Alzheimer’s disease.

Badea, A., Kane, L., Anderson, R. J., Qi, Y., Foster, M., Cofer, G. P., Medvitz, N., Buckley, A. F., Badea, A. K., Wetsel, W. C., et al. (2016) · NeuroImage

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 39

Differential Regulation of MeCP2 Phosphorylation in the CNS by Dopamine and Serotonin

Hutchinson, A. N., Deng, J. V., Aryal, D. K., Wetsel, W. C., & West, A. E. (2012) · Neuropsychopharmacology

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 31

Reversal of cocaine sensitization-induced behavioral sensitization normalizes GAD67 and GABAA receptor α2 subunit expression, and PKC ζ activity

Chen, Q., Lee, T. H., Wetsel, W. C., Sun, Q.-A., Liu, Y., Davidson, C., Xiong, X., Ellinwood, E. H., & Zhang, X. (2007) · Biochemical and Biophysical Research Communications

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 30