Brown, Alistair J. P.
University of Exeter · MRC Centre for Medical Mycology
51 papers on CoChatORCID 0000-0003-1406-4251
Most cited papers
- Verified
A hyphal-specific chitin synthase gene (CHS2) is not essential for growth, dimorphism, or virulence of Candida albicans
Gow, N. A., Robbins, P. W., Lester, J. W., Brown, A. J., Fonzi, W. A., Chapman, T., & Kinsman, O. S. (1994) · Proceedings of the National Academy of Sciences
Fungal and yeast genetics researchAntifungal resistance and susceptibility
Cited by 145
- Verified
Hypoxia Promotes Immune Evasion by Triggering β-Glucan Masking on the Candida albicans Cell Surface via Mitochondrial and cAMP-Protein Kinase A Signaling
Pradhan, A., Avelar, G. M., Bain, J. M., Childers, D. S., Larcombe, D. E., Netea, M. G., Shekhova, E., Munro, C. A., Brown, G. D., Erwig, L. P., et al. (2018) · mBio
Fungal and yeast genetics researchAntifungal resistance and susceptibility
Cited by 133
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A Multifunctional Mannosyltransferase Family in Candida albicans Determines Cell Wall Mannan Structure and Host-Fungus Interactions
Mora-Montes, H. M., Bates, S., Netea, M. G., Castillo, L., Brand, A., Buurman, E. T., Díaz-Jiménez, D. F., Jan Kullberg, B., Brown, A. J. P., Odds, F. C., et al. (2010) · Journal of Biological Chemistry
Fungal and yeast genetics researchGlycosylation and Glycoproteins Research
Cited by 129
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The Mnn2 Mannosyltransferase Family Modulates Mannoprotein Fibril Length, Immune Recognition and Virulence of Candida albicans
Hall, R. A., Bates, S., Lenardon, M. D., MacCallum, D. M., Wagener, J., Lowman, D. W., Kruppa, M. D., Williams, D. L., Odds, F. C., Brown, A. J. P., et al. (2013) · PLoS Pathogens
Fungal and yeast genetics researchGlycosylation and Glycoproteins Research
Cited by 128
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Non-canonical signalling mediates changes in fungal cell wall PAMPs that drive immune evasion
Pradhan, A., Avelar, G. M., Bain, J. M., Childers, D., Pelletier, C., Larcombe, D. E., Shekhova, E., Netea, M. G., Brown, G. D., Erwig, L., et al. (2019) · Nature Communications
Fungal and yeast genetics researchAntifungal resistance and susceptibility
Cited by 119
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Impact of the unfolded protein response upon genome-wide expression patterns, and the role of Hac1 in the polarized growth, of Candida albicans
Wimalasena, T. T., Enjalbert, B., Guillemette, T., Plumridge, A., Budge, S., Yin, Z., Brown, A. J. P., & Archer, D. B. (2008) · Fungal Genetics and Biology
Endoplasmic Reticulum Stress and DiseaseFungal and yeast genetics research
Cited by 118
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Exposure of Candida albicans to antifungal agents affects expression of SAP2 and SAP9 secreted proteinase genes
Copping, V. M. S., Barelle, C. J., Hube, B., Gow, N. A. R., Brown, A. J. P., & Odds, F. C. (2005) · Journal of Antimicrobial Chemotherapy
Antifungal resistance and susceptibilityFungal and yeast genetics research
Cited by 113
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Scalar nanostructure of the Candida albicans cell wall; a molecular, cellular and ultrastructural analysis and interpretation
Lenardon, M. D., Sood, P., Dorfmueller, H. C., Brown, A. J. P., & Gow, N. A. R. (2020) · The Cell Surface
Fungal and yeast genetics researchAntifungal resistance and susceptibility
Cited by 110
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Fungal Hsp90: a biological transistor that tunes cellular outputs to thermal inputs
Leach, M. D., Klipp, E., Cowen, L. E., & Brown, A. J. P. (2012) · Nature Reviews Microbiology
Heat shock proteins researchFungal and yeast genetics research
Cited by 107
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Role of the heat shock transcription factor, Hsf1, in a major fungal pathogen that is obligately associated with warm‐blooded animals
Nicholls, S., Leach, M. D., Priest, C. L., & Brown, A. J. P. (2009) · Molecular Microbiology
Heat shock proteins researchFungal and yeast genetics research
Cited by 105
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Structure and regulation of the HSP90 gene from the pathogenic fungus Candida albicans
Swoboda, R. K., Bertram, G., Budge, S., Gooday, G. W., Gow, N. A., & Brown, A. J. (1995) · Infection and Immunity
Heat shock proteins researchFungal and yeast genetics research
Cited by 89
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Combinatorial stresses kill pathogenic Candida species
Kaloriti, D., Tillmann, A., Cook, E., Jacobsen, M., You, T., Lenardon, M., Ames, L., Barahona, M., Chandrasekaran, K., Coghill, G., et al. (2012) · Medical Mycology
Fungal and yeast genetics researchAntifungal resistance and susceptibility
Cited by 86
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Pseudomonas aeruginosa secreted factors impair biofilm development in Candida albicans
Holcombe, L. J., McAlester, G., Munro, C. A., Enjalbert, B., Brown, A. J. P., Gow, N. A. R., Ding, C., Butler, G., O'Gara, F., & Morrissey, J. P. (2010) · Microbiology
Bacterial biofilms and quorum sensingAntifungal resistance and susceptibility
Cited by 82
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The Rewiring of Ubiquitination Targets in a Pathogenic Yeast Promotes Metabolic Flexibility, Host Colonization and Virulence
Childers, D. S., Raziunaite, I., Mol Avelar, G., Mackie, J., Budge, S., Stead, D., Gow, N. A. R., Lenardon, M. D., Ballou, E. R., MacCallum, D. M., et al. (2016) · PLOS Pathogens
Fungal and yeast genetics researchAntifungal resistance and susceptibility
Cited by 81
- Verified
C andida albicans colonization and dissemination from the murine gastrointestinal tract: the influence of morphology and Th17 immunity: Candida albicans colonization and dissemination from the GI tract
Vautier, S., Drummond, R. A., Chen, K., Murray, G. I., Kadosh, D., Brown, A. J. P., Gow, N. A. R., MacCallum, D. M., Kolls, J. K., & Brown, G. D. (2015) · Cellular Microbiology
Antifungal resistance and susceptibilityFungal and yeast genetics research
Cited by 72
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Fungal iron availability during deep seated candidiasis is defined by a complex interplay involving systemic and local events
Potrykus, J., Stead, D., MacCallum, D. M., Urgast, D. S., Raab, A., van Rooijen, N., Feldmann, J., & Brown, A. J. P. (2013) · PLoS Pathogens
Antifungal resistance and susceptibilityFungal Infections and Studies
Cited by 66
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Functional specialization and differential regulation of short‐chain carboxylic acid transporters in the pathogen Candida albicans
Vieira, N., Casal, M., Johansson, B., MacCallum, D. M., Brown, A. J. P., & Paiva, S. (2010) · Molecular Microbiology
Fungal and yeast genetics researchAntifungal resistance and susceptibility
Cited by 63
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Modelling the Regulation of Thermal Adaptation in Candida albicans, a Major Fungal Pathogen of Humans
Leach, M. D., Tyc, K. M., Brown, A. J. P., & Klipp, E. (2012) · PLoS ONE
Heat shock proteins researchFungal and yeast genetics research
Cited by 61
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Conflicting interests in the pathogen–host tug of war: fungal micronutrient scavenging versus mammalian nutritional immunity
Potrykus, J., Ballou, E. R., Childers, D. S., & Brown, A. J. P. (2014) · PLoS Pathogens
Fungal Infections and StudiesAntifungal resistance and susceptibility
Cited by 52
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Glyoxylate cycle gene ICL1 is essential for the metabolic flexibility and virulence of Candida glabrata
Chew, S. Y., Ho, K. L., Cheah, Y. K., Ng, T. S., Sandai, D., Brown, A. J. P., & Than, L. T. L. (2019) · Scientific Reports
Antifungal resistance and susceptibilityFungal and yeast genetics research
Cited by 49
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Candida glabrata susceptibility to antifungals and phagocytosis is modulated by acetate
Mota, S., Alves, R., Carneiro, C., Silva, S., Brown, A. J., Istel, F., Kuchler, K., Sampaio, P., Casal, M., Henriques, M., et al. (2015) · Frontiers in Microbiology
Antifungal resistance and susceptibilityFungal and yeast genetics research
Cited by 49
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Candida auris undergoes adhesin-dependent and -independent cellular aggregation
Pelletier, C., Shaw, S., Alsayegh, S., Brown, A. J. P., & Lorenz, A. (2024) · PLOS Pathogens
Antifungal resistance and susceptibilityFungal and yeast genetics research
Cited by 44
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Cell wall protection by the Candida albicans class I chitin synthases
Preechasuth, K., Anderson, J. C., Peck, S. C., Brown, A. J. P., Gow, N. A. R., & Lenardon, M. D. (2015) · Fungal Genetics and Biology
Fungal and yeast genetics researchAntifungal resistance and susceptibility
Cited by 43
- Verified
Physiologically relevant alternative carbon sources modulate biofilm formation, Cell Wall architecture, and the stress and antifungal resistance of Candida glabrata
Chew, S. Y., Ho, K. L., Cheah, Y. K., Sandai, D., Brown, A. J. P., & Than, L. T. L. (2019) · International Journal of Molecular Sciences
Antifungal resistance and susceptibilityFungal and yeast genetics research
Cited by 40
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