Justice, Jamie N.

Senolytics in idiopathic pulmonary fibrosis: Results from a first-in-human, open-label, pilot study

Justice, J. N., Nambiar, A. M., Tchkonia, T., LeBrasseur, N. K., Pascual, R., Hashmi, S. K., Prata, L., Masternak, M. M., Kritchevsky, S. B., Musi, N., et al. (2019) · EBioMedicine

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisTelomeres, Telomerase, and Senescence

Cited by 1,261

Validation of biomarkers of aging

Moqri, M., Herzog, C., Poganik, J. R., Ying, K., Justice, J. N., Belsky, D. W., Higgins-Chen, A. T., Chen, B. H., Cohen, A. A., Fuellen, G., et al. (2024) · Nature Medicine

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 361

A framework for selection of blood-based biomarkers for geroscience-guided clinical trials: report from the TAME Biomarkers Workgroup

Justice, J. N., Ferrucci, L., Newman, A. B., Aroda, V. R., Bahnson, J. L., Divers, J., Espeland, M. A., Marcovina, S., Pollak, M. N., Kritchevsky, S. B., et al. (2018) · GeroScience

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 359

Physiological Aging: Links Among Adipose Tissue Dysfunction, Diabetes, and Frailty

Stout, M. B., Justice, J. N., Nicklas, B. J., & Kirkland, J. L. (2017) · Physiology

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 272

Exercise Intolerance in Older Adults With Heart Failure With Preserved Ejection Fraction

Pandey, A., Shah, S. J., Butler, J., Kellogg, D. L., Lewis, G. D., Forman, D. E., Mentz, R. J., Borlaug, B. A., Simon, M. A., Chirinos, J. A., et al. (2021) · Journal of the American College of Cardiology

Cardiovascular and exercise physiologyHeart Failure Treatment and Management

Cited by 184

Cellular senescence biomarker p16INK4a+ cell burden in thigh adipose is associated with poor physical function in older women

Justice, J. N., Gregory, H., Tchkonia, T., LeBrasseur, N. K., Kirkland, J. L., Kritchevsky, S. B., & Nicklas, B. J. (2018) · The Journals of Gerontology: Series A

Telomeres, Telomerase, and SenescenceNutrition and Health in Aging

Cited by 129

NIH SenNet Consortium to map senescent cells throughout the human lifespan to understand physiological health.

SenNet Consortium, Writing Group, Lee, P. J., Benz, C. C., Blood, P., Börner, K., Campisi, J., Chen, F., Daldrup-Link, H., De Jager, P., et al. (2022) · Nature Aging

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 122

Orally-active, clinically-translatable senolytics restore α-Klotho in mice and humans

Zhu, Y., Prata, L. G. P. L., Gerdes, E. O. W., Netto, J. M. E., Pirtskhalava, T., Giorgadze, N., Tripathi, U., Inman, C. L., Johnson, K. O., Xue, A., et al. (2022) · EBioMedicine

Telomeres, Telomerase, and SenescenceParathyroid Disorders and Treatments

Cited by 100

Frameworks for proof-of-concept clinical trials of interventions that target fundamental aging processes

Justice, J., Miller, J. D., Newman, J. C., Hashmi, S. K., Halter, J., Austad, S. N., Barzilai, N., & Kirkland, J. L. (2016) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 96

Development of clinical trials to extend healthy lifespan

Justice, J. N., Niedernhofer, L., Robbins, P. D., Aroda, V. R., Espeland, M. A., Kritchevsky, S. B., Kuchel, G. A., & Barzilai, N. (2018) · Cardiovascular Endocrinology & Metabolism

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 84

Lipotoxicity, aging, and muscle contractility: does fiber type matter?

Carter, C. S., Justice, J. N., & Thompson, L. (2019) · GeroScience

Nutrition and Health in AgingMuscle Physiology and Disorders

Cited by 66

Evaluating Health Span in Preclinical Models of Aging and Disease: Guidelines, Challenges, and Opportunities for Geroscience

Huffman, D. M., Justice, J. N., Stout, M. B., Kirkland, J. L., Barzilai, N., & Austad, S. N. (2016) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 52

Commentaries on Viewpoint: Can elite athletes benefit from dietary nitrate supplementation?

Hultström, M., de Paula, C. A., Fontes, M. A. P., Porcelli, S., Bellistri, G., Pugliese, L., Rasica, L., Marzorati, M., Pavei, G., Ferguson, S. K., et al. (2015) · Journal of Applied Physiology

Exercise and Physiological ResponsesMuscle metabolism and nutrition

Cited by 19

Cities, communities and clinics can be testbeds for human exposome and aging research

Woods, T., Palmarini, N., Corner, L., Barzilai, N., Maier, A. B., Sagner, M., Bensz, J., Strygin, A., Yadala, N., Kern, C., et al. (2025) · Nature Medicine

Health, Environment, Cognitive AgingGenetics, Aging, and Longevity in Model Organisms

Cited by 13