Keller, Andreas

Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment

Schulte-Schrepping, J., Reusch, N., Paclik, D., Baßler, K., Schlickeiser, S., Zhang, B., Krämer, B., Krammer, T., Brumhard, S., Bonaguro, L., et al. (2020) · Cell

COVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 Research

Cited by 1,461

A single-cell transcriptomic atlas characterizes ageing tissues in the mouse

The Tabula Muris Consortium, Almanzar, N., Antony, J., Baghel, A. S., Bakerman, I., Bansal, I., Barres, B. A., Beachy, P. A., Berdnik, D., Bilen, B., et al. (2020) · Nature

Single-cell and spatial transcriptomicsGenetics, Aging, and Longevity in Model Organisms

Cited by 1,247

Undulating changes in human plasma proteome profiles across the lifespan

Lehallier, B., Gate, D., Schaum, N., Nanasi, T., Lee, S. E., Yousef, H., Moran Losada, P., Berdnik, D., Keller, A., Verghese, J., et al. (2019) · Nature Medicine

Genetics, Aging, and Longevity in Model OrganismsAdvanced Proteomics Techniques and Applications

Cited by 981

Distribution of miRNA expression across human tissues

Ludwig, N., Leidinger, P., Becker, K., Backes, C., Fehlmann, T., Pallasch, C., Rheinheimer, S., Meder, B., Stähler, C., Meese, E., et al. (2016) · Nucleic Acids Research

MicroRNA in disease regulationGene expression and cancer classification

Cited by 968

Swarm Learning for decentralized and confidential clinical machine learning

Warnat-Herresthal, S., Schultze, H., Shastry, K. L., Manamohan, S., Mukherjee, S., Garg, V., Sarveswara, R., Händler, K., Pickkers, P., Aziz, N. A., et al. (2021) · Nature

Privacy-Preserving Technologies in DataBlockchain Technology Applications and Security

Cited by 884

A human brain vascular atlas reveals diverse mediators of Alzheimer’s risk

Yang, A. C., Vest, R. T., Kern, F., Lee, D. P., Agam, M., Maat, C. A., Losada, P. M., Chen, M. B., Schaum, N., Khoury, N., et al. (2022) · Nature

Barrier Structure and Function StudiesAlzheimer's disease research and treatments

Cited by 797

Dysregulation of brain and choroid plexus cell types in severe COVID-19

Yang, A. C., Kern, F., Losada, P. M., Agam, M. R., Maat, C. A., Schmartz, G. P., Fehlmann, T., Stein, J. A., Schaum, N., Lee, D. P., et al. (2021) · Nature

Long-Term Effects of COVID-19Single-cell and spatial transcriptomics

Cited by 620

An estimate of the total number of true human miRNAs

Alles, J., Fehlmann, T., Fischer, U., Backes, C., Galata, V., Minet, M., Hart, M., Abu-Halima, M., Grässer, F. A., Lenhof, H.-P., et al. (2019) · Nucleic Acids Research

MicroRNA in disease regulationPlant Molecular Biology Research

Cited by 567

New insights into the Tyrolean Iceman's origin and phenotype as inferred by whole-genome sequencing

Keller, A., Graefen, A., Ball, M., Matzas, M., Boisguerin, V., Maixner, F., Leidinger, P., Backes, C., Khairat, R., Forster, M., et al. (2012) · Nature Communications

Forensic and Genetic ResearchPaleopathology and ancient diseases

Cited by 437

Toward the blood-borne miRNome of human diseases

Keller, A., Leidinger, P., Bauer, A., ElSharawy, A., Haas, J., Backes, C., Wendschlag, A., Giese, N., Tjaden, C., Ott, K., et al. (2011) · Nature Methods

MicroRNA in disease regulationGene expression and cancer classification

Cited by 355

Atlas of the aging mouse brain reveals white matter as vulnerable foci

Hahn, O., Foltz, A. G., Atkins, M., Kedir, B., Moran-Losada, P., Guldner, I. H., Munson, C., Kern, F., Pálovics, R., Lu, N., et al. (2023) · Cell

Single-cell and spatial transcriptomicsGenetics, Aging, and Longevity in Model Organisms

Cited by 213

miRTargetLink 2.0—interactive miRNA target gene and target pathway networks

Kern, F., Aparicio-Puerta, E., Li, Y., Fehlmann, T., Kehl, T., Wagner, V., Ray, K., Ludwig, N., Lenhof, H.-P., Meese, E., et al. (2021) · Nucleic Acids Research

MicroRNA in disease regulationBioinformatics and Genomic Networks

Cited by 205

Molecular hallmarks of heterochronic parabiosis at single-cell resolution

Pálovics, R., Keller, A., Schaum, N., Tan, W., Fehlmann, T., Borja, M., Kern, F., Bonanno, L., Calcuttawala, K., Webber, J., et al. (2022) · Nature

Genetics, Aging, and Longevity in Model OrganismsSingle-cell and spatial transcriptomics

Cited by 153

miRNATissueAtlas2: an update to the human miRNA tissue atlas

Keller, A., Gröger, L., Tschernig, T., Solomon, J., Laham, O., Schaum, N., Wagner, V., Kern, F., Schmartz, G. P., Li, Y., et al. (2022) · Nucleic Acids Research

MicroRNA in disease regulationCancer-related molecular mechanisms research

Cited by 143

A mouse tissue atlas of small noncoding RNA

Isakova, A., Fehlmann, T., Keller, A., & Quake, S. R. (2020) · Proceedings of the National Academy of Sciences

MicroRNA in disease regulationCancer-related molecular mechanisms research

Cited by 119

Influence of the Confounding Factors Age and Sex on MicroRNA Profiles from Peripheral Blood

Meder, B., Backes, C., Haas, J., Leidinger, P., Stähler, C., Großmann, T., Vogel, B., Frese, K., Giannitsis, E., Katus, H. A., et al. (2014) · Clinical Chemistry

MicroRNA in disease regulationGene expression and cancer classification

Cited by 112

Effects of Resistant Starch on Symptoms, Fecal Markers, and Gut Microbiota in Parkinson’s Disease — The RESISTA-PD Trial

Becker, A., Schmartz, G. P., Gröger, L., Grammes, N., Galata, V., Philippeit, H., Weiland, J., Ludwig, N., Meese, E., Tierling, S., et al. (2022) · Genomics, Proteomics & Bioinformatics

Gut microbiota and healthParkinson's Disease Mechanisms and Treatments

Cited by 102

Effects of Resistant Starch on Symptoms, Fecal Markers and Gut Microbiota in Parkinson’s Disease – The RESISTA-PD Trial

Becker, A., Schmartz, G. P., Gröger, L., Grammes, N., Galata, V., Philippeit, H., Weiland, J., Ludwig, N., Meese, E., Tierling, S., et al. (2021) · Genomics Proteomics & Bioinformatics

Gut microbiota and healthParkinson's Disease Mechanisms and Treatments

Cited by 102

Characterizing expression changes in noncoding RNAs during aging and heterochronic parabiosis across mouse tissues

Wagner, V., Kern, F., Hahn, O., Schaum, N., Ludwig, N., Fehlmann, T., Engel, A., Henn, D., Rishik, S., Isakova, A., et al. (2024) · Nature Biotechnology

Genetics, Aging, and Longevity in Model OrganismsMicroRNA in disease regulation

Cited by 72

The human miRNA repertoire of different blood compounds

Leidinger, P., Backes, C., Meder, B., Meese, E., & Keller, A. (2014) · BMC Genomics

MicroRNA in disease regulationExtracellular vesicles in disease

Cited by 67

Abnormal neovascular and proliferative conjunctival phenotype in limbal stem cell deficiency is associated with altered microRNA and gene expression modulated by PAX6 mutational status in congenital aniridia

Latta, L., Ludwig, N., Krammes, L., Stachon, T., Fries, F. N., Mukwaya, A., Szentmáry, N., Seitz, B., Wowra, B., Kahraman, M., et al. (2021) · The Ocular Surface

Ocular Disorders and TreatmentsCorneal Surgery and Treatments

Cited by 59

On the lifetime of bioinformatics web services

Kern, F., Fehlmann, T., & Keller, A. (2020) · Nucleic Acids Research

Scientific Computing and Data ManagementWeb visibility and informetrics

Cited by 50

A human brain vascular atlas reveals diverse cell mediators of Alzheimer’s disease risk

Yang, A. C., Vest, R. T., Kern, F., Lee, D. P., Maat, C. A., Losada, P. M., Chen, M. B., Agam, M., Schaum, N., Khoury, N., et al. (2021) · bioRxiv (Cold Spring Harbor Laboratory)

Barrier Structure and Function StudiesSingle-cell and spatial transcriptomics

Cited by 48

miRSwitch: detecting microRNA arm shift and switch events

Kern, F., Amand, J., Senatorov, I., Isakova, A., Backes, C., Meese, E., Keller, A., & Fehlmann, T. (2020) · Nucleic Acids Research

MicroRNA in disease regulationPlant Molecular Biology Research

Cited by 31