Zheng, Yi

Rational design and characterization of a Rac GTPase-specific small molecule inhibitor

Gao, Y., Dickerson, J. B., Guo, F., Zheng, J., & Zheng, Y. (2004) · Proceedings of the National Academy of Sciences

Protein Kinase Regulation and GTPase SignalingProtein Tyrosine Phosphatases

Cited by 1,091

Cdc42 activity regulates hematopoietic stem cell aging and rejuvenation

Florian, M. C., Dörr, K., Niebel, A., Daria, D., Schrezenmeier, H., Rojewski, M., Filippi, M.-D., Hasenberg, A., Gunzer, M., Scharffetter-Kochanek, K., et al. (2012) · Cell Stem Cell

Hematopoietic Stem Cell TransplantationMesenchymal stem cell research

Cited by 564

Rac1 GTPase: A “Rac” of All Trades

Bosco, E. E., Mulloy, J. C., & Zheng, Y. (2009) · Cellular and Molecular Life Sciences

Protein Kinase Regulation and GTPase SignalingCellular transport and secretion

Cited by 350

A canonical to non-canonical Wnt signalling switch in haematopoietic stem-cell ageing

Florian, M. C., Nattamai, K. J., Dörr, K., Marka, G., Überle, B., Vas, V., Eckl, C., Andrä, I., Schiemann, M., Oostendorp, R. A. J., et al. (2013) · Nature

Hematopoietic Stem Cell TransplantationWnt/β-catenin signaling in development and cancer

Cited by 303

Cloning and Characterization of GEF-H1, a Microtubule-associated Guanine Nucleotide Exchange Factor for Rac and Rho GTPases

Ren, Y., Li, R., Zheng, Y., & Busch, H. (1998) · Journal of Biological Chemistry

Protein Kinase Regulation and GTPase SignalingCellular transport and secretion

Cited by 295

Canonical Wnt Signaling Ameliorates Aging of Intestinal Stem Cells

Nalapareddy, K., Nattamai, K. J., Kumar, R. S., Karns, R., Wikenheiser-Brokamp, K. A., Sampson, L. L., Mahe, M. M., Sundaram, N., Yacyshyn, M.-B., Yacyshyn, B., et al. (2017) · Cell Reports

Wnt/β-catenin signaling in development and cancerGenetics, Aging, and Longevity in Model Organisms

Cited by 280

Interactions between the bud emergence proteins Bem1p and Bem2p and Rho-type GTPases in yeast.

Peterson, J., Zheng, Y., Bender, L., Myers, A., Cerione, R., & Bender, A. (1994) · The Journal of cell biology

Fungal and yeast genetics researchProtein Kinase Regulation and GTPase Signaling

Cited by 197

Adaptive response to inflammation contributes to sustained myelopoiesis and confers a competitive advantage in myelodysplastic syndrome HSCs

Muto, T., Walker, C. S., Choi, K., Hueneman, K., Smith, M. A., Gul, Z., Garcia-Manero, G., Ma, A., Zheng, Y., & Starczynowski, D. T. (2020) · Nature Immunology

Acute Myeloid Leukemia ResearchHematopoietic Stem Cell Transplantation

Cited by 155

Structure and mutagenesis of the Dbl homology domain

Aghazadeh, B., Zhu, K., Kubiseski, T. J., Liu, G. A., Pawson, T., Zheng, Y., & Rosen, M. K. (1998) · Nature Structural Biology

Protein Kinase Regulation and GTPase SignalingProtein Structure and Dynamics

Cited by 145

Trp56 of Rac1 Specifies Interaction with a Subset of Guanine Nucleotide Exchange Factors

Gao, Y., Xing, J., Streuli, M., Leto, T. L., & Zheng, Y. (2001) · Journal of Biological Chemistry

Protein Kinase Regulation and GTPase SignalingCellular transport and secretion

Cited by 115

Cryptococcus neoformans phospholipase B1 activates host cell Rac1 for traversal across the blood-brain barrier: Role of PLB1 in C. neoformans meningoencephalitis

Maruvada, R., Zhu, L., Pearce, D., Zheng, Y., Perfect, J., Kwon-Chung, K. J., & Kim, K. S. (2012) · Cellular Microbiology

Fungal Infections and StudiesBarrier Structure and Function Studies

Cited by 75

Residues of the Rho Family GTPases Rho and Cdc42 That Specify Sensitivity to Dbl-like Guanine Nucleotide Exchange Factors

Li, R., & Zheng, Y. (1997) · Journal of Biological Chemistry

Protein Kinase Regulation and GTPase SignalingCellular transport and secretion

Cited by 67

Characterization of a Brain-specific Rho GTPase-activating Protein, p200RhoGAP

Moon, S. Y., Zang, H., & Zheng, Y. (2003) · Journal of Biological Chemistry

Protein Kinase Regulation and GTPase SignalingCellular Mechanics and Interactions

Cited by 58

Serine phosphorylation differentially affects RhoA binding to effectors: Implications to NGF-induced neurite outgrowth

Nusser, N., Gosmanova, E., Makarova, N., Fujiwara, Y., Yang, L., Guo, F., Luo, Y., Zheng, Y., & Tigyi, G. (2006) · Cellular Signalling

Protein Kinase Regulation and GTPase SignalingAxon Guidance and Neuronal Signaling

Cited by 57

Targeting multiple cell death pathways extends the shelf life and preserves the function of human and mouse neutrophils for transfusion

Fan, Y., Teng, Y., Loison, F., Pang, A., Kasorn, A., Shao, X., Zhang, C., Ren, Q., Yu, H., Zheng, Y., et al. (2021) · Science Translational Medicine

Cell death mechanisms and regulationBlood transfusion and management

Cited by 36

RhoH GTPase: A Key Regulator of Hematopoietic Cell Proliferation and Apoptosis?

Gu, Y., Zheng, Y., & Williams, D. A. (2005) · Cell Cycle

Protein Kinase Regulation and GTPase SignalingCellular transport and secretion

Cited by 20

Graded RhoA GTPase Expression in Treg Cells Distinguishes Tumor Immunity From Autoimmunity

Kalim, K. W., Yang, J.-Q., Modur, V., Nguyen, P., Li, Y., Zheng, Y., & Guo, F. (2021) · Frontiers in Immunology

T-cell and B-cell ImmunologyCancer Immunotherapy and Biomarkers

Cited by 10