Ajami, Nadim J.

Gut microbiome modulates response to anti-PD-1 immunotherapy in melanoma patients

Gopalakrishnan, V., Spencer, C. N., Nezi, L., Reuben, A., Andrews, M. C., Karpinets, T. V., Prieto, P. A., Vicente, D., Hoffman, K., Wei, S. C., et al. (2018) · Science

Cancer Immunotherapy and BiomarkersGut microbiota and health

Cited by 4,812

Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases

Lloyd-Price, J., Arze, C., Ananthakrishnan, A. N., Schirmer, M., Avila-Pacheco, J., Poon, T. W., Andrews, E., Ajami, N. J., Bonham, K. S., Brislawn, C. J., et al. (2019) · Nature

Gut microbiota and healthInflammatory Bowel Disease

Cited by 3,143

Fecal microbiota transplant promotes response in immunotherapy-refractory melanoma patients

Baruch, E. N., Youngster, I., Ben-Betzalel, G., Ortenberg, R., Lahat, A., Katz, L., Adler, K., Dick-Necula, D., Raskin, S., Bloch, N., et al. (2021) · Science

Cancer Immunotherapy and BiomarkersGut microbiota and health

Cited by 1,757

Tumor Microbiome Diversity and Composition Influence Pancreatic Cancer Outcomes

Riquelme, E., Zhang, Y., Zhang, L., Montiel, M., Zoltan, M., Dong, W., Quesada, P., Sahin, I., Chandra, V., San Lucas, A., et al. (2019) · Cell

Gut microbiota and healthPancreatic and Hepatic Oncology Research

Cited by 1,577

Microbial reconstitution reverses maternal diet-induced social and synaptic deficits in offspring

Buffington, S. A., Di Prisco, G. V., Auchtung, T. A., Ajami, N. J., Petrosino, J. F., & Costa-Mattioli, M. (2016) · Cell

Gut microbiota and healthNeuroendocrine regulation and behavior

Cited by 1,163

Dietary fiber and probiotics influence the gut microbiome and melanoma immunotherapy response

Spencer, C. N., McQuade, J. L., Gopalakrishnan, V., McCulloch, J. A., Vetizou, M., Cogdill, A. P., Khan, M. A. W., Zhang, X., White, M. G., Peterson, C. B., et al. (2021) · Science

Cancer Immunotherapy and BiomarkersGut microbiota and health

Cited by 966

Wild Mouse Gut Microbiota Promotes Host Fitness and Improves Disease Resistance

Rosshart, S. P., Vassallo, B. G., Angeletti, D., Hutchinson, D. S., Morgan, A. P., Takeda, K., Hickman, H. D., McCulloch, J. A., Badger, J. H., Ajami, N. J., et al. (2017) · Cell

Gut microbiota and healthAnimal Nutrition and Physiology

Cited by 862

Neoadjuvant nivolumab or nivolumab plus ipilimumab in operable non-small cell lung cancer: the phase 2 randomized NEOSTAR trial

Cascone, T., William, W. N., Weissferdt, A., Leung, C. H., Lin, H. Y., Pataer, A., Godoy, M. C. B., Carter, B. W., Federico, L., Reuben, A., et al. (2021) · Nature Medicine

Cancer Immunotherapy and BiomarkersLung Cancer Diagnosis and Treatment

Cited by 618

Gut microbiota signatures are associated with toxicity to combined CTLA-4 and PD-1 blockade

Andrews, M. C., Duong, C. P. M., Gopalakrishnan, V., Iebba, V., Chen, W.-S., Derosa, L., Khan, M. A. W., Cogdill, A. P., White, M. G., Wong, M. C., et al. (2021) · Nature Medicine

Cancer Immunotherapy and BiomarkersGut microbiota and health

Cited by 437

Gut Microbiome Associates With Lifetime Cardiovascular Disease Risk Profile Among Bogalusa Heart Study Participants

Kelly, T. N., Bazzano, L. A., Ajami, N. J., He, H., Zhao, J., Petrosino, J. F., Correa, A., & He, J. (2016) · Circulation Research

Gut microbiota and healthOral microbiology and periodontitis research

Cited by 345

Role of the Gut Microbiome in Obstructive Sleep Apnea–Induced Hypertension

Durgan, D. J., Ganesh, B. P., Cope, J. L., Ajami, N. J., Phillips, S. C., Petrosino, J. F., Hollister, E. B., & Bryan, R. M. (2016) · Hypertension

Gut microbiota and healthObstructive Sleep Apnea Research

Cited by 327

Diet-driven microbial ecology underpins associations between cancer immunotherapy outcomes and the gut microbiome

Simpson, R. C., Shanahan, E. R., Batten, M., Reijers, I. L. M., Read, M., Silva, I. P., Versluis, J. M., Ribeiro, R., Angelatos, A. S., Tan, J., et al. (2022) · Nature Medicine

Gut microbiota and healthCancer Immunotherapy and Biomarkers

Cited by 256

A combined risk score enhances prediction of type 1 diabetes among susceptible children

Ferrat, L. A., Vehik, K., Sharp, S. A., Lernmark, Å., Rewers, M. J., She, J.-X., Ziegler, A.-G., Toppari, J., Akolkar, B., Krischer, J. P., et al. (2020) · Nature Medicine

Diabetes and associated disordersDiabetes Management and Research

Cited by 148

Dendritic cell–derived hepcidin sequesters iron from the microbiota to promote mucosal healing

Bessman, N. J., Mathieu, J. R. R., Renassia, C., Zhou, L., Fung, T. C., Fernandez, K. C., Austin, C., Moeller, J. B., Zumerle, S., Louis, S., et al. (2020) · Science

Iron Metabolism and DisordersInflammatory Bowel Disease

Cited by 145

Gut microbiome diversity is an independent predictor of survival in cervical cancer patients receiving chemoradiation

Sims, T. T., El Alam, M. B., Karpinets, T. V., Dorta-Estremera, S., Hegde, V. L., Nookala, S., Yoshida-Court, K., Wu, X., Biegert, G. W. G., Delgado Medrano, A. Y., et al. (2021) · Communications Biology

Gut microbiota and healthCancer Immunotherapy and Biomarkers

Cited by 135

Randomized Placebo-Controlled, Biomarker-Stratified Phase Ib Microbiome Modulation in Melanoma: Impact of Antibiotic Preconditioning on Microbiome and Immunity

Glitza, I. C., Seo, Y. D., Spencer, C. N., Wortman, J. R., Burton, E. M., Alayli, F. A., Loo, C. P., Gautam, S., Damania, A., Densmore, J., et al. (2024) · Cancer Discovery

Cancer Immunotherapy and BiomarkersGut microbiota and health

Cited by 87

Adaptive changes in the gut microbiome during standard-of-care chemoradiotherapy for gynecologic cancers

El Alam, M. B., Sims, T. T., Kouzy, R., Biegert, G. W. G., Abi Jaoude, J., Karpinets, T. V., Yoshida-Court, K., Wu, X., Delgado Medrano, A. Y., Mezzari, M. P., et al. (2020) · PLoS ONE

Gut microbiota and healthReproductive tract infections research

Cited by 41

Diversity and composition of gut microbiome of cervical cancer patients: Do results of 16S rRNA sequencing and whole genome sequencing approaches align?

Biegert, G., El Alam, M. B., Karpinets, T., Wu, X., Sims, T. T., Yoshida-Court, K., Lynn, E. J., Yue, J., Medrano, A. D., Petrosino, J., et al. (2021) · Journal of Microbiological Methods

Gut microbiota and healthGenomics and Phylogenetic Studies

Cited by 24

Maternal Fish Consumption in Pregnancy Is Associated with a Bifidobacterium-Dominant Microbiome Profile in Infants

Simione, M., Harshman, S. G., Castro, I., Linnemann, R., Roche, B., Ajami, N. J., Petrosino, J. F., Raspini, B., Portale, S., Camargo, Jr., et al. (2020) · Current Developments in Nutrition

Gut microbiota and healthInfant Nutrition and Health

Cited by 13

Diversity and composition of gut microbiome of cervical cancer patients by 16S rRNA and whole-metagenome sequencing

Biegert, G., Karpinets, T., Wu, X., Alam, M. B. E., Sims, T. T., Yoshida-Court, K., Lynn, E. J., Yue, J., Medrano, A. D., Petrosino, J., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory)

Gut microbiota and healthMicrobial Community Ecology and Physiology

Cited by 1

Gut microbiota: a new factor modulating the immunizing potential of viral and cancer vaccines

Zitvogel, L., Carrier, A., Manghi, P., Silva, C. A. C., Lahmar, I., Birebent, R., Suissa, D., Laheurte, C., Schreibelt, G., Lemant, L., et al. (2025) · Research Square

Gut microbiota and healthImmune responses and vaccinations

Cited by 1