Kishimoto, Tadamitsu

Interleukin 6 plays a key role in the development of antigen-induced arthritis

Ohshima, S., Saeki, Y., Mima, T., Sasai, M., Nishioka, K., Nomura, S., Kopf, M., Katada, Y., Tanaka, T., Suemura, M., et al. (1998) · Proceedings of the National Academy of Sciences

Rheumatoid Arthritis Research and TherapiesCytokine Signaling Pathways and Interactions

Cited by 406

Historical overview of the interleukin-6 family cytokine

Kang, S., Narazaki, M., Metwally, H., & Kishimoto, T. (2020) · Journal of Experimental Medicine

Cytokine Signaling Pathways and InteractionsRheumatoid Arthritis Research and Therapies

Cited by 360

A member of the C/EBP family, NF-IL6 beta, forms a heterodimer and transcriptionally synergizes with NF-IL6.

Kinoshita, S., Akira, S., & Kishimoto, T. (1992) · Proceedings of the National Academy of Sciences

Cytokine Signaling Pathways and InteractionsGenomics and Chromatin Dynamics

Cited by 327

Activation of JAK2 kinase mediated by the interleukin 6 signal transducer gp130.

Narazaki, M., Witthuhn, B. A., Yoshida, K., Silvennoinen, O., Yasukawa, K., Ihle, J. N., Kishimoto, T., & Taga, T. (1994) · Proceedings of the National Academy of Sciences

Cytokine Signaling Pathways and InteractionsReceptor Mechanisms and Signaling

Cited by 299

Regulation of IL-6 in Immunity and Diseases

Tanaka, T., Narazaki, M., Masuda, K., & Kishimoto, T. (2016) · Advances in Experimental Medicine and Biology

Cytokine Signaling Pathways and InteractionsNF-κB Signaling Pathways

Cited by 235

Generation of plasmacytomas with the chromosomal translocation t(12;15) in interleukin 6 transgenic mice

Suematsu, S., Matsusaka, T., Matsuda, T., Ohno, S., Miyazaki, J., Yamamura, K., Hirano, T., & Kishimoto, T. (1992) · Proceedings of the National Academy of Sciences

Multiple Myeloma Research and TreatmentsLymphoma Diagnosis and Treatment

Cited by 227

Arid5a controls IL-6 mRNA stability, which contributes to elevation of IL-6 level in vivo

Masuda, K., Ripley, B., Nishimura, R., Mino, T., Takeuchi, O., Shioi, G., Kiyonari, H., & Kishimoto, T. (2013) · Proceedings of the National Academy of Sciences

RNA Research and SplicingCytokine Signaling Pathways and Interactions

Cited by 226

Regulation of synthesis and secretion of major rat acute‐phase proteins by recombinant human interleukin‐6 (BSF‐2/1L‐6) in hepatocyte primary cultures

ANDUS, T., GEIGER, T., HIRANO, T., KISHIMOTO, T., TRAN‐THI, T., DECKER, K., & HEINRICH, P. C. (1988) · European Journal of Biochemistry

Cytokine Signaling Pathways and InteractionsLiver physiology and pathology

Cited by 188

IL-6 Revisited: From Rheumatoid Arthritis to CAR T Cell Therapy and COVID-19

Kishimoto, T., & Kang, S. (2022) · Annual Review of Immunology

Cytokine Signaling Pathways and InteractionsRheumatoid Arthritis Research and Therapies

Cited by 140

Four Tyrosine Residues in Phospholipase C-γ2, Identified as Btk-dependent Phosphorylation Sites, Are Required for B Cell Antigen Receptor-coupled Calcium Signaling

Watanabe, D., Hashimoto, S., Ishiai, M., Matsushita, M., Baba, Y., Kishimoto, T., Kurosaki, T., & Tsukada, S. (2001) · Journal of Biological Chemistry

Protein Kinase Regulation and GTPase SignalingT-cell and B-cell Immunology

Cited by 136

ANTI-INTERLEUKIN 6 (IL-6) RECEPTOR ANTIBODY SUPPRESSES CASTLEMAN'S DISEASE LIKE SYMPTOMS EMERGED IN IL-6 TRANSGENIC MICE

Katsume, A., Saito, H., Yamada, Y., Yorozu, K., Ueda, O., Akamatsu, K.-I., Nishimoto, N., Kishimoto, T., Yoshizaki, K., & Ohsugi, Y. (2002) · Cytokine

Cytokine Signaling Pathways and InteractionsRheumatoid Arthritis Research and Therapies

Cited by 134

IFN Regulatory Factor-1-Mediated Transcriptional Activation of Mouse STAT-Induced STAT Inhibitor-1 Gene Promoter by IFN-γ

Saito, H., Morita, Y., Fujimoto, M., Narazaki, M., Naka, T., & Kishimoto, T. (2000) · The Journal of Immunology

Cytokine Signaling Pathways and Interactionsinterferon and immune responses

Cited by 97

Interleukin-6.

Hirano, T., & Kishimoto, T. (1990) · Handbook of Experimental Pharmacology

Cytokine Signaling Pathways and InteractionsRheumatoid Arthritis Research and Therapies

Cited by 57