Zhao, Yingming

Metabolic regulation of gene expression by histone lactylation

Zhang, D., Tang, Z., Huang, H., Zhou, G., Cui, C., Weng, Y., Liu, W., Kim, S., Lee, S., Perez-Neut, M., et al. (2019) · Nature

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 4,371

Identification of 67 Histone Marks and Histone Lysine Crotonylation as a New Type of Histone Modification

Tan, M., Luo, H., Lee, S., Jin, F., Yang, J. S., Montellier, E., Buchou, T., Cheng, Z., Rousseaux, S., Rajagopal, N., et al. (2011) · Cell

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 1,902

Substrate and Functional Diversity of Lysine Acetylation Revealed by a Proteomics Survey

Kim, S. C., Sprung, R., Chen, Y., Xu, Y., Ball, H., Pei, J., Cheng, T., Kho, Y., Xiao, H., Xiao, L., et al. (2006) · Molecular Cell

Advanced Proteomics Techniques and ApplicationsUbiquitin and proteasome pathways

Cited by 1,487

Integrated Proteogenomic Characterization of Human High-Grade Serous Ovarian Cancer

Zhang, H., Liu, T., Zhang, Z., Payne, S. H., Zhang, B., McDermott, J. E., Zhou, J.-Y., Petyuk, V. A., Chen, L., Ray, D., et al. (2016) · Cell

Ovarian cancer diagnosis and treatmentAdvanced Proteomics Techniques and Applications

Cited by 1,029

Identification of lysine succinylation as a new post-translational modification

Zhang, Z., Tan, M., Xie, Z., Dai, L., Chen, Y., & Zhao, Y. (2011) · Nature Chemical Biology

Advanced Proteomics Techniques and ApplicationsCancer-related gene regulation

Cited by 1,027

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways

Park, J., Chen, Y., Tishkoff, D. X., Peng, C., Tan, M., Dai, L., Xie, Z., Zhang, Y., Zwaans, B. M. M., Skinner, M. E., et al. (2013) · Molecular Cell

Sirtuins and Resveratrol in MedicineCancer-related gene regulation

Cited by 1,000

Tumor Suppression in the Absence of p53-Mediated Cell-Cycle Arrest, Apoptosis, and Senescence

Li, T., Kon, N., Jiang, L., Tan, M., Ludwig, T., Zhao, Y., Baer, R., & Gu, W. (2012) · Cell

Cancer-related Molecular PathwaysTelomeres, Telomerase, and Senescence

Cited by 912

Lysine glutarylation is a protein posttranslational modification regulated by SIRT5

Tan, M., Peng, C., Anderson, K. A., Chhoy, P., Xie, Z., Dai, L., Park, J., Chen, Y., Huang, H., Zhang, Y., et al. (2014) · Cell Metabolism

Sirtuins and Resveratrol in MedicineCancer-related gene regulation

Cited by 844

Class I histone deacetylases (HDAC1–3) are histone lysine delactylases

Moreno-Yruela, C., Zhang, D., Wei, W., Bæk, M., Liu, W., Gao, J., Danková, D., Nielsen, A. L., Bolding, J. E., Yang, L., et al. (2022) · Science Advances

Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics

Cited by 841

Acetylation Is Indispensable for p53 Activation

Tang, Y., Zhao, W., Chen, Y., Zhao, Y., & Gu, W. (2008) · Cell

Cancer-related Molecular PathwaysHeat shock proteins research

Cited by 838

Proteogenomic Analysis of Human Colon Cancer Reveals New Therapeutic Opportunities

Vasaikar, S., Huang, C., Wang, X., Petyuk, V. A., Savage, S. R., Wen, B., Dou, Y., Zhang, Y., Shi, Z., Arshad, O. A., et al. (2019) · Cell

Advanced Proteomics Techniques and ApplicationsCancer Genomics and Diagnostics

Cited by 799

Lysine propionylation and butyrylation are novel post-translational modifications in histones

Chen, Y., Sprung, R., Tang, Y., Ball, H., Sangras, B., Kim, S. C., Falck, J. R., Peng, J., Gu, W., & Zhao, Y. (2007) · Molecular & Cellular Proteomics

Genomics and Chromatin DynamicsCancer-related gene regulation

Cited by 764

The first identification of lysine malonylation substrates and its regulatory enzyme

Peng, C., Lu, Z., Xie, Z., Cheng, Z., Chen, Y., Tan, M., Luo, H., Zhang, Y., He, W., Yang, K., et al. (2011) · Molecular & Cellular Proteomics

Advanced Proteomics Techniques and ApplicationsCancer-related gene regulation

Cited by 751

Metabolic Regulation of Gene Expression by Histone Lysine β-Hydroxybutyrylation

Xie, Z., Zhang, D., Chung, D., Tang, Z., Huang, H., Dai, L., Qi, S., Li, J., Colak, G., Chen, Y., et al. (2016) · Molecular Cell

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 744

TEAD/TEF transcription factors utilize the activation domain of YAP65, a Src/Yes-associated protein localized in the cytoplasm

Vassilev, A., Kaneko, K. J., Shu, H., Zhao, Y., & DePamphilis, M. L. (2001) · Genes & Development

Hippo pathway signaling and YAP/TAZGenomics and Chromatin Dynamics

Cited by 719

Intracellular Crotonyl-CoA Stimulates Transcription through p300-Catalyzed Histone Crotonylation

Sabari, B. R., Tang, Z., Huang, H., Yong-Gonzalez, V., Molina, H., Kong, H. E., Dai, L., Shimada, M., Cross, J. R., Zhao, Y., et al. (2015) · Molecular Cell

Genomics and Chromatin DynamicsHistone Deacetylase Inhibitors Research

Cited by 659

Lysine succinylation and lysine malonylation in histones

Xie, Z., Dai, J., Dai, L., Tan, M., Cheng, Z., Wu, Y., Boeke, J. D., & Zhao, Y. (2012) · Molecular & Cellular Proteomics

Genomics and Chromatin DynamicsAdvanced Proteomics Techniques and Applications

Cited by 613

SnapShot: histone modifications

Huang, H., Sabari, B. R., Garcia, B. A., Allis, C. D., & Zhao, Y. (2014) · Cell

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 439

Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain

Li, Y., Sabari, B. R., Panchenko, T., Wen, H., Zhao, D., Guan, H., Wan, L., Huang, H., Tang, Z., Zhao, Y., et al. (2016) · Molecular Cell

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 384

Modification‐specific proteomics: Strategies for characterization of post‐translational modifications using enrichment techniques

Zhao, Y., & Jensen, O. N. (2009) · PROTEOMICS

Advanced Proteomics Techniques and ApplicationsRedox biology and oxidative stress

Cited by 384

SIRT1 collaborates with ATM and HDAC1 to maintain genomic stability in neurons

Dobbin, M. M., Madabhushi, R., Pan, L., Chen, Y., Kim, D., Gao, J., Ahanonu, B., Pao, P.-C., Qiu, Y., Zhao, Y., et al. (2013) · Nature Neuroscience

DNA Repair MechanismsSirtuins and Resveratrol in Medicine

Cited by 250

HDAC8 catalyzes the hydrolysis of long chain fatty acyl lysine

Aramsangtienchai, P., Spiegelman, N. A., He, B., Miller, S. P., Dai, L., Zhao, Y., & Lin, H. (2016) · ACS Chemical Biology

Histone Deacetylase Inhibitors ResearchSirtuins and Resveratrol in Medicine

Cited by 118

Histone crotonylation specifically marks the haploid male germ cell gene expression program: Post‐meiotic male‐specific gene expression

Montellier, E., Rousseaux, S., Zhao, Y., & Khochbin, S. (2012) · BioEssays

Sperm and Testicular FunctionGenomics and Chromatin Dynamics

Cited by 116

Antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells

Head, S. A., Shi, W., Zhao, L., Gorshkov, K., Pasunooti, K., Chen, Y., Deng, Z., Li, R.-J., Shim, J. S., Tan, W., et al. (2015) · Proceedings of the National Academy of Sciences

PI3K/AKT/mTOR signaling in cancerAngiogenesis and VEGF in Cancer

Cited by 111