Tammela, Tuomas

CRISPR-mediated direct mutation of cancer genes in the mouse liver

Xue, W., Chen, S., Yin, H., Tammela, T., Papagiannakopoulos, T., Joshi, N. S., Cai, W., Yang, G., Bronson, R., Crowley, D. G., et al. (2014) · Nature

CRISPR and Genetic EngineeringCancer Genomics and Diagnostics

Cited by 776

VEGFR-3 controls tip to stalk conversion at vessel fusion sites by reinforcing Notch signalling

Tammela, T., Zarkada, G., Nurmi, H., Jakobsson, L., Heinolainen, K., Tvorogov, D., Zheng, W., Franco, C. A., Murtomäki, A., Aranda, E., et al. (2011) · Nature Cell Biology

Angiogenesis and VEGF in CancerLymphatic System and Diseases

Cited by 321

Notum produced by Paneth cells attenuates regeneration of aged intestinal epithelium

Pentinmikko, N., Iqbal, S., Mana, M., Andersson, S., Cognetta, A. B., Suciu, R. M., Roper, J., Luopajärvi, K., Markelin, E., Gopalakrishnan, S., et al. (2019) · Nature

Wnt/β-catenin signaling in development and cancerDigestive system and related health

Cited by 271

WNT as a Driver and Dependency in Cancer

Parsons, M. J., Tammela, T., & Dow, L. E. (2021) · Cancer Discovery

Wnt/β-catenin signaling in development and cancerHedgehog Signaling Pathway Studies

Cited by 257

Effects of Angiopoietin-2-Blocking Antibody on Endothelial Cell–Cell Junctions and Lung Metastasis

Holopainen, T., Saharinen, P., D’Amico, G., Lampinen, A., Eklund, L., Sormunen, R., Anisimov, A., Zarkada, G., Lohela, M., Heloterä, H., et al. (2012) · JNCI: Journal of the National Cancer Institute

Angiogenesis and VEGF in CancerLymphatic System and Diseases

Cited by 216

Notch restricts lymphatic vessel sprouting induced by vascular endothelial growth factor

Zheng, W., Tammela, T., Yamamoto, M., Anisimov, A., Holopainen, T., Kaijalainen, S., Karpanen, T., Lehti, K., Ylä-Herttuala, S., & Alitalo, K. (2011) · Blood

Lymphatic System and DiseasesAngiogenesis and VEGF in Cancer

Cited by 132

A Classical Epithelial State Drives Acute Resistance to KRAS Inhibition in Pancreatic Cancer

Singhal, A., Styers, H. C., Rub, J., Li, Z., Torborg, S. R., Kim, J. Y., Grbovic-Huezo, O., Feng, H., Tarcan, Z. C., Sahin Ozkan, H., et al. (2024) · Cancer Discovery

Pancreatic and Hepatic Oncology ResearchCancer Cells and Metastasis

Cited by 84

Alveolar Differentiation Drives Resistance to KRAS Inhibition in Lung Adenocarcinoma

Li, Z., Zhuang, X., Pan, C.-H., Yan, Y., Thummalapalli, R., Hallin, J., Torborg, S., Singhal, A., Chang, J. C., Manchado, E., et al. (2024) · Cancer Discovery

Lung Cancer Treatments and MutationsCancer Cells and Metastasis

Cited by 74

Clonal dynamics following p53 loss of heterozygosity in Kras-driven cancers

Muzumdar, M. D., Dorans, K. J., Chung, K. M., Robbins, R., Tammela, T., Gocheva, V., Li, C. M.-C., & Jacks, T. (2016) · Nature Communications

Cancer Genomics and DiagnosticsCancer-related Molecular Pathways

Cited by 72