Schübeler, Dirk

Function and information content of DNA methylation

Schübeler, D. (2015) · Nature

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 2,060

DNA-binding factors shape the mouse methylome at distal regulatory regions

Stadler, M. B., Murr, R., Burger, L., Ivanek, R., Lienert, F., Schöler, A., Nimwegen, E. V., Wirbelauer, C., Oakeley, E. J., Gaidatzis, D., et al. (2011) · Nature

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 1,383

Impact of cytosine methylation on DNA binding specificities of human transcription factors

Yin, Y., Morgunova, E., Jolma, A., Kaasinen, E., Sahu, B., Khund-Sayeed, S., Das, P. K., Kivioja, T., Dave, K., Zhong, F., et al. (2017) · Science

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 1,257

Genomic profiling of DNA methyltransferases reveals a role for DNMT3B in genic methylation

Baubec, T., Colombo, D. F., Wirbelauer, C., Schmidt, J., Burger, L., Krebs, A. R., Akalin, A., & Schübeler, D. (2015) · Nature

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 705

Repressive and active histone methylation mark distinct promoters in human and mouse spermatozoa

Brykczynska, U., Hisano, M., Erkek, S., Ramos, L., Oakeley, E. J., Roloff, T. C., Beisel, C., Schübeler, D., Stadler, M. B., & Peters, A. H. F. M. (2010) · Nature Structural & Molecular Biology

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 680

Competition between DNA methylation and transcription factors determines binding of NRF1

Domcke, S., Bardet, A. F., Adrian Ginno, P., Hartl, D., Burger, L., & Schübeler, D. (2015) · Nature

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 508

Characterizing Light-Regulated Retinal MicroRNAs Reveals Rapid Turnover as a Common Property of Neuronal MicroRNAs

Krol, J., Busskamp, V., Markiewicz, I., Stadler, M. B., Ribi, S., Richter, J., Duebel, J., Bicker, S., Fehling, H. J., Schübeler, D., et al. (2010) · Cell

MicroRNA in disease regulationRetinal Development and Disorders

Cited by 470

YAP1 Exerts Its Transcriptional Control via TEAD-Mediated Activation of Enhancers

Stein, C., Bardet, A. F., Roma, G., Bergling, S., Clay, I., Ruchti, A., Agarinis, C., Schmelzle, T., Bouwmeester, T., Schübeler, D., et al. (2015) · PLOS Genetics

Hippo pathway signaling and YAP/TAZGenomics and Chromatin Dynamics

Cited by 414

Methylation-Dependent and -Independent Genomic Targeting Principles of the MBD Protein Family

Baubec, T., Ivánek, R., Lienert, F., & Schübeler, D. (2013) · Cell

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 365

Genome-wide Single-Molecule Footprinting Reveals High RNA Polymerase II Turnover at Paused Promoters

Krebs, A. R., Imanci, D., Hoerner, L., Gaidatzis, D., Burger, L., & Schübeler, D. (2017) · Molecular Cell

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 249

Targeting neuronal and glial cell types with synthetic promoter AAVs in mice, non-human primates and humans

Jüttner, J., Szabo, A., Gross-Scherf, B., Morikawa, R. K., Rompani, S. B., Hantz, P., Szikra, T., Esposti, F., Cowan, C. S., Bharioke, A., et al. (2019) · Nature Neuroscience

Virus-based gene therapy researchRetinal Development and Disorders

Cited by 218

Aging-Dependent Demethylation of Regulatory Elements Correlates with Chromatin State and Improved β Cell Function

Avrahami, D., Li, C., Zhang, J., Schug, J., Avrahami, R., Rao, S., Stadler, M. B., Burger, L., Schübeler, D., Glaser, B., et al. (2015) · Cell Metabolism

Epigenetics and DNA MethylationPancreatic function and diabetes

Cited by 207

Genomic Targeting of Methylated DNA: Influence of Methylation on Transcription, Replication, Chromatin Structure, and Histone Acetylation

Schübeler, D., Lorincz, M. C., Cimbora, D. M., Telling, A., Feng, Y.-Q., Bouhassira, E. E., & Groudine, M. (2000) · Molecular and Cellular Biology

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 165

Molecular Co-occupancy Identifies Transcription Factor Binding Cooperativity In Vivo

Sönmezer, C., Kleinendorst, R., Imanci, D., Barzaghi, G., Villacorta, L., Schübeler, D., Benes, V., Molina, N., & Krebs, A. R. (2021) · Molecular Cell

Genomics and Chromatin DynamicsDiffusion and Search Dynamics

Cited by 162

Pioneering Activity of the C-Terminal Domain of EBF1 Shapes the Chromatin Landscape for B Cell Programming

Boller, S., Ramamoorthy, S., Akbas, D., Nechanitzky, R., Burger, L., Murr, R., Schübeler, D., & Grosschedl, R. (2016) · Immunity

Genomics and Chromatin DynamicsT-cell and B-cell Immunology

Cited by 133

Cell cycle-resolved chromatin proteomics reveals the extent of mitotic preservation of the genomic regulatory landscape

Ginno, P. A., Burger, L., Seebacher, J., Iesmantavicius, V., & Schübeler, D. (2018) · Nature Communications

Genomics and Chromatin DynamicsAdvanced Proteomics Techniques and Applications

Cited by 91

The murine β-globin locus control region regulates the rate of transcription but not the hyperacetylation of histones at the active genes

Schübeler, D., Groudine, M., & Bender, M. A. (2001) · Proceedings of the National Academy of Sciences

Genomics and Chromatin DynamicsHemoglobinopathies and Related Disorders

Cited by 87

High-throughput engineering of a mammalian genome reveals building principles of methylation states at CG rich regions

Krebs, A. R., Dessus-Babus, S., Burger, L., & Schübeler, D. (2014) · eLife

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 81

Protein Complex Interactor Analysis and Differential Activity of KDM3 Subfamily Members Towards H3K9 Methylation

Brauchle, M., Yao, Z., Arora, R., Thigale, S., Clay, I., Inverardi, B., Fletcher, J., Taslimi, P., Acker, M. G., Gerrits, B., et al. (2013) · PLoS ONE

Epigenetics and DNA MethylationCancer-related gene regulation

Cited by 79

Cis-regulatory landscapes of four cell types of the retina

Hartl, D., Krebs, A. R., Jüttner, J., Roska, B., & Schübeler, D. (2017) · Nucleic Acids Research

Genomics and Chromatin DynamicsRetinal Development and Disorders

Cited by 37