Bechmann, Ingo

Microglia states and nomenclature: A field at its crossroads

Paolicelli, R. C., Sierra, A., Stevens, B., Tremblay, M.-E., Aguzzi, A., Ajami, B., Amit, I., Audinat, E., Bechmann, I., Bennett, M., et al. (2022) · Neuron

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 1,973

Origin, fate and dynamics of macrophages at central nervous system interfaces

Goldmann, T., Wieghofer, P., Jordão, M. J. C., Prutek, F., Hagemeyer, N., Frenzel, K., Amann, L., Staszewski, O., Kierdorf, K., Krueger, M., et al. (2016) · Nature Immunology

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 1,209

What is immune privilege (not)?

Galea, I., Bechmann, I., & Perry, V. H. (2007) · Trends in Immunology

Neuroinflammation and Neurodegeneration MechanismsBarrier Structure and Function Studies

Cited by 768

Dystrophic (senescent) rather than activated microglial cells are associated with tau pathology and likely precede neurodegeneration in Alzheimer’s disease

Streit, W. J., Braak, H., Xue, Q.-S., & Bechmann, I. (2009) · Acta Neuropathologica

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 727

Targeting gene-modified hematopoietic cells to the central nervous system: use of green fluorescent protein uncovers microglial engraftment

Priller, J., Flügel, A., Wehner, T., Boentert, M., Haas, C. A., Prinz, M., Fernández-Klett, F., Prass, K., Bechmann, I., de Boer, B. A., et al. (2001) · Nature Medicine

Virus-based gene therapy researchBarrier Structure and Function Studies

Cited by 637

TGF- receptor-mediated albumin uptake into astrocytes is involved in neocortical epileptogenesis

Ivens, S., Kaufer, D., Flores, L. P., Bechmann, I., Zumsteg, D., Tomkins, O., Seiffert, E., Heinemann, U., & Friedman, A. (2007) · Brain

Epilepsy research and treatmentBarrier Structure and Function Studies

Cited by 567

Cellular mechanisms of IL-17-induced blood-brain barrier disruption

Huppert, J., Closhen, D., Croxford, A., White, R., Kulig, P., Pietrowski, E., Bechmann, I., Becher, B., Luhmann, H. J., Waisman, A., et al. (2010) · The FASEB Journal

Barrier Structure and Function StudiesMultiple Sclerosis Research Studies

Cited by 529

What is the blood–brain barrier (not)?

Bechmann, I., Galea, I., & Perry, V. H. (2007) · Trends in Immunology

Barrier Structure and Function StudiesDrug Transport and Resistance Mechanisms

Cited by 520

Panoptic imaging of transparent mice reveals whole-body neuronal projections and skull–meninges connections

Cai, R., Pan, C., Ghasemigharagoz, A., Todorov, M. I., Förstera, B., Zhao, S., Bhatia, H. S., Parra-Damas, A., Mrowka, L., Theodorou, D., et al. (2019) · Nature Neuroscience

Advanced Fluorescence Microscopy TechniquesCell Image Analysis Techniques

Cited by 470

Anorectic estrogen mimics leptin's effect on the rewiring of melanocortin cells and Stat3 signaling in obese animals

Gao, Q., Mezei, G., Nie, Y., Rao, Y., Choi, C. S., Bechmann, I., Leranth, C., Toran-Allerand, D., Priest, C. A., Roberts, J. L., et al. (2007) · Nature Medicine

Regulation of Appetite and ObesityHypothalamic control of reproductive hormones

Cited by 416

Alu Elements in ANRIL Non-Coding RNA at Chromosome 9p21 Modulate Atherogenic Cell Functions through Trans-Regulation of Gene Networks

Holdt, L. M., Hoffmann, S., Sass, K., Langenberger, D., Scholz, M., Krohn, K., Finstermeier, K., Stahringer, A., Wilfert, W., Beutner, F., et al. (2013) · PLoS Genetics

Cancer-related molecular mechanisms researchAtherosclerosis and Cardiovascular Diseases

Cited by 397

Effector T-cell trafficking between the leptomeninges and the cerebrospinal fluid

Schläger, C., Körner, H., Krueger, M., Vidoli, S., Haberl, M., Mielke, D., Brylla, E., Issekutz, T., Cabañas, C., Nelson, P. J., et al. (2016) · Nature

Multiple Sclerosis Research StudiesT-cell and B-cell Immunology

Cited by 372

Vascular, glial, and lymphatic immune gateways of the central nervous system

Engelhardt, B., Carare, R. O., Bechmann, I., Flügel, A., Laman, J. D., & Weller, R. O. (2016) · Acta Neuropathologica

Barrier Structure and Function StudiesCerebrospinal fluid and hydrocephalus

Cited by 362

Distinct and Non-Redundant Roles of Microglia and Myeloid Subsets in Mouse Models of Alzheimer's Disease

Mildner, A., Schlevogt, B., Kierdorf, K., Böttcher, C., Erny, D., Kummer, M. P., Quinn, M., Brück, W., Bechmann, I., Heneka, M. T., et al. (2011) · The Journal of Neuroscience

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 351

Sickle Hemoglobin Confers Tolerance to Plasmodium Infection

Ferreira, A., Marguti, I., Bechmann, I., Jeney, V., Chora, Â., Palha, N. R., Rebelo, S., Henri, A., Beuzard, Y., & Soares, M. P. (2011) · Cell

Malaria Research and ControlHemoglobinopathies and Related Disorders

Cited by 340

Microglial pathology

Streit, W. J., Xue, Q.-S., Tischer, J., & Bechmann, I. (2014) · Acta Neuropathologica Communications

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 317

Cellular and Molecular Probing of Intact Human Organs

Zhao, S., Todorov, M. I., Cai, R., -Maskari, R. A., Steinke, H., Kemter, E., Mai, H., Rong, Z., Warmer, M., Stanic, K., et al. (2020) · Cell

Advanced Fluorescence Microscopy TechniquesSingle-cell and spatial transcriptomics

Cited by 292

Beyond Activation: Characterizing Microglial Functional Phenotypes

Lier, J., Streit, W. J., & Bechmann, I. (2021) · Cells

Neuroinflammation and Neurodegeneration MechanismsNeurological Disease Mechanisms and Treatments

Cited by 274

CXCR3-Dependent Microglial Recruitment Is Essential for Dendrite Loss after Brain Lesion

Rappert, A., Bechmann, I., Pivneva, T., Mahlo, J., Biber, K., Nolte, C., Kovac, A. D., Gerard, C., Boddeke, H. W. G. M., Nitsch, R., et al. (2004) · The Journal of Neuroscience

Neuroinflammation and Neurodegeneration MechanismsChemokine receptors and signaling

Cited by 259

TREM2 is upregulated in amyloid plaque-associated microglia in aged APP23 transgenic mice

Frank, S., Burbach, G. J., Bonin, M., Walter, M., Streit, W., Bechmann, I., & Deller, T. (2008) · Glia

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 247

Perivascular spaces—MRI marker of inflammatory activity in the brain?

Wuerfel, J., Haertle, M., Waiczies, H., Tysiak, E., Bechmann, I., Wernecke, K. D., Zipp, F., & Paul, F. (2008) · Brain

Multiple Sclerosis Research StudiesCerebrospinal fluid and hydrocephalus

Cited by 244

Re-evaluating microglia expression profiles using RiboTag and cell isolation strategies

Haimon, Z., Volaski, A., Orthgiess, J., Boura-Halfon, S., Varol, D., Shemer, A., Yona, S., Zuckerman, B., David, E., Chappell-Maor, L., et al. (2018) · Nature Immunology

Single-cell and spatial transcriptomicsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 209

Hypothalamic innate immune reaction in obesity

Kälin, S., Heppner, F. L., Bechmann, I., Prinz, M., Tschöp, M. H., & Yi, C.-X. (2015) · Nature Reviews Endocrinology

Regulation of Appetite and ObesityAdipokines, Inflammation, and Metabolic Diseases

Cited by 167

Dystrophic microglia in late‐onset Alzheimer's disease

Streit, W. J., Khoshbouei, H., & Bechmann, I. (2020) · Glia

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 152