Kabashima, Kenji

Atopic dermatitis

Weidinger, S., Beck, L. A., Bieber, T., Kabashima, K., & Irvine, A. D. (2018) · Nature Reviews Disease Primers

Dermatology and Skin DiseasesContact Dermatitis and Allergies

Cited by 1,549

Anti-PD-1 and Anti-CTLA-4 Therapies in Cancer: Mechanisms of Action, Efficacy, and Limitations

Seidel, J. A., Otsuka, A., & Kabashima, K. (2018) · Frontiers in Oncology

Cancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses

Cited by 1,360

Two distinct interstitial macrophage populations coexist across tissues in specific subtissular niches

Chakarov, S., Lim, H. Y., Tan, L., Lim, S. Y., See, P., Lum, J., Zhang, X.-M., Foo, S., Nakamizo, S., Duan, K., et al. (2019) · Science

Immune cells in cancerPhagocytosis and Immune Regulation

Cited by 1,114

The Asian atopic dermatitis phenotype combines features of atopic dermatitis and psoriasis with increased TH17 polarization

Noda, S., Suárez-Fariñas, M., Ungar, B., Kim, S. J., de Guzman Strong, C., Xu, H., Peng, X., Estrada, Y. D., Nakajima, S., Honda, T., et al. (2015) · Journal of Allergy and Clinical Immunology

Dermatology and Skin DiseasesPsoriasis: Treatment and Pathogenesis

Cited by 657

The immunological anatomy of the skin

Kabashima, K., Honda, T., Ginhoux, F., & Egawa, G. (2019) · Nature Reviews Immunology

Dermatology and Skin DiseasesT-cell and B-cell Immunology

Cited by 650

Anti–Interleukin-31 Receptor A Antibody for Atopic Dermatitis

Ruzicka, T., Hanifin, J. M., Furue, M., Pulka, G., Mlynarczyk, I., Wollenberg, A., Galus, R., Etoh, T., Mihara, R., Yoshida, H., et al. (2017) · New England Journal of Medicine

Dermatology and Skin DiseasesAsthma and respiratory diseases

Cited by 592

Germline NLRP1 Mutations Cause Skin Inflammatory and Cancer Susceptibility Syndromes via Inflammasome Activation

Zhong, F. L., Mamaï, O., Sborgi, L., Boussofara, L., Hopkins, R., Robinson, K., Szeverényi, I., Takeichi, T., Balaji, R., Lau, A., et al. (2016) · Cell

Inflammasome and immune disordersGenetic and rare skin diseases.

Cited by 440

Safety and efficacy of upadacitinib in combination with topical corticosteroids in adolescents and adults with moderate-to-severe atopic dermatitis (AD Up): results from a randomised, double-blind, placebo-controlled, phase 3 trial

Reich, K., Teixeira, H. D., de Bruin-Weller, M., Bieber, T., Soong, W., Kabashima, K., Werfel, T., Zeng, J., Huang, X., Hu, X., et al. (2021) · The Lancet

Dermatology and Skin DiseasesAsthma and respiratory diseases

Cited by 402

Baricitinib in patients with moderate‐to‐severe atopic dermatitis and inadequate response to topical corticosteroids: results from two randomized monotherapy phase III trials

Simpson, E. L., Lacour, J. ‐., Spelman, L., Galimberti, R., Eichenfield, L. F., Bissonnette, R., King, B. A., Thyssen, J. P., Silverberg, J. I., Bieber, T., et al. (2020) · British Journal of Dermatology

Dermatology and Skin DiseasesPsoriasis: Treatment and Pathogenesis

Cited by 396

Trial of Nemolizumab and Topical Agents for Atopic Dermatitis with Pruritus

Kabashima, K., Matsumura, T., Komazaki, H., & Kawashima, M. (2020) · New England Journal of Medicine

Dermatology and Skin DiseasesAsthma and respiratory diseases

Cited by 361

Biomarkers in atopic dermatitis—a review on behalf of the International Eczema Council

Renert-Yuval, Y., Thyssen, J. P., Bissonnette, R., Bieber, T., Kabashima, K., Hijnen, D., & Guttman-Yassky, E. (2021) · Journal of Allergy and Clinical Immunology

Dermatology and Skin DiseasesAsthma and respiratory diseases

Cited by 350

Multifactorial skin barrier deficiency and atopic dermatitis: Essential topics to prevent the atopic march

Egawa, G., & Kabashima, K. (2016) · Journal of Allergy and Clinical Immunology

Dermatology and Skin DiseasesContact Dermatitis and Allergies

Cited by 265

The Janus kinase inhibitor JTE-052 improves skin barrier function through suppressing signal transducer and activator of transcription 3 signaling

Amano, W., Nakajima, S., Kunugi, H., Numata, Y., Kitoh, A., Egawa, G., Dainichi, T., Honda, T., Otsuka, A., Kimoto, Y., et al. (2015) · Journal of Allergy and Clinical Immunology

Dermatology and Skin DiseasesContact Dermatitis and Allergies

Cited by 259

Nemolizumab in patients with moderate-to-severe atopic dermatitis: Randomized, phase II, long-term extension study

Kabashima, K., Furue, M., Hanifin, J. M., Pulka, G., Wollenberg, A., Galus, R., Etoh, T., Mihara, R., Nakano, M., & Ruzicka, T. (2018) · Journal of Allergy and Clinical Immunology

Dermatology and Skin DiseasesAsthma and respiratory diseases

Cited by 248

Therapeutic pipeline for atopic dermatitis: End of the drought?

Paller, A. S., Kabashima, K., & Bieber, T. (2017) · Journal of Allergy and Clinical Immunology

Dermatology and Skin DiseasesPsoriasis: Treatment and Pathogenesis

Cited by 192

The etiopathogenesis of atopic dermatitis: barrier disruption, immunological derangement, and pruritus

Rerknimitr, P., Otsuka, A., Nakashima, C., & Kabashima, K. (2017) · Inflammation and Regeneration

Dermatology and Skin DiseasesContact Dermatitis and Allergies

Cited by 187

Interleukin‐31 and interleukin‐31 receptor: New therapeutic targets for atopic dermatitis

Nakashima, C., Otsuka, A., & Kabashima, K. (2018) · Experimental Dermatology

Dermatology and Skin DiseasesPsoriasis: Treatment and Pathogenesis

Cited by 154

Prostaglandin E2–EP3 Signaling Induces Inflammatory Swelling by Mast Cell Activation

Morimoto, K., Shirata, N., Taketomi, Y., Tsuchiya, S., Segi-Nishida, E., Inazumi, T., Kabashima, K., Tanaka, S., Murakami, M., Narumiya, S., et al. (2014) · The Journal of Immunology

Mast cells and histamineInflammatory mediators and NSAID effects

Cited by 132

THBS1-producing tumor-infiltrating monocyte-like cells contribute to immunosuppression and metastasis in colorectal cancer

Omatsu, M., Nakanishi, Y., Iwane, K., Aoyama, N., Duran, A., Muta, Y., Martinez-Ordoñez, A., Han, Q., Agatsuma, N., Mizukoshi, K., et al. (2023) · Nature Communications

Immune cells in cancerCancer Immunotherapy and Biomarkers

Cited by 109

Peripheral blood Th9 cells are a possible pharmacodynamic biomarker of nivolumab treatment efficacy in metastatic melanoma patients

Nonomura, Y., Otsuka, A., Nakashima, C., Seidel, J. A., Kitoh, A., Dainichi, T., Nakajima, S., Sawada, Y., Matsushita, S., Aoki, M., et al. (2016) · OncoImmunology

Cancer Immunotherapy and BiomarkersT-cell and B-cell Immunology

Cited by 83

Hedgehog signaling in basal cell carcinoma

Otsuka, A., Levesque, M. P., Dummer, R., & Kabashima, K. (2015) · Journal of Dermatological Science

Hedgehog Signaling Pathway StudiesNonmelanoma Skin Cancer Studies

Cited by 72

Infiltration of PD-1-positive cells in combination with tumor site PD-L1 expression is a positive prognostic factor in cutaneous angiosarcoma

Honda, Y., Otsuka, A., Ono, S., Yamamoto, Y., Seidel, J. A., Morita, S., Hirata, M., Kataoka, T. R., Takenouchi, T., Fujii, K., et al. (2017) · OncoImmunology

Vascular Tumors and AngiosarcomasCancer Immunotherapy and Biomarkers

Cited by 72

Advances in atopic dermatitis in 2015

Nomura, T., & Kabashima, K. (2016) · Journal of Allergy and Clinical Immunology

Dermatology and Skin DiseasesContact Dermatitis and Allergies

Cited by 60

Linking air pollution to atopic dermatitis

Kabashima, K., Otsuka, A., & Nomura, T. (2017) · Nature Immunology

Dermatology and Skin DiseasesContact Dermatitis and Allergies

Cited by 47