Thal, Dietmar Rudolf
Universitair Ziekenhuis Leuven · KU Leuven
58 papers on CoChatORCID 0000-0002-1036-1075
Most cited papers
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Mutant valosin‐containing protein causes a novel type of frontotemporal dementia
Schröder, R., Watts, G. D. J., Mehta, S. G., Evert, B. O., Broich, P., Fließbach, K., Pauls, K., Hans, V. H., Kimonis, V., & Thal, D. R. (2005) · Annals of Neurology
Amyotrophic Lateral Sclerosis ResearchAlzheimer's disease research and treatments
Cited by 177
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PART, a distinct tauopathy, different from classical sporadic Alzheimer disease.
Jellinger, K. A., Alafuzoff, I., Attems, J., Beach, T. G., Cairns, N. J., Crary, J. F., Dickson, D. W., Hof, P. R., Hyman, B. T., Jack, C. R., et al. (2015) · Acta Neuropathologica
Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research
Cited by 171
- Verified
Pathological consequences of VCP mutations on human striated muscle
Hubbers, C. U., Clemen, C. S., Kesper, K., Boddrich, A., Hofmann, A., Kamarainen, O., Tolksdorf, K., Stumpf, M., Reichelt, J., Roth, U., et al. (2007) · Brain
Muscle Physiology and DisordersGenetic Neurodegenerative Diseases
Cited by 170
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[ 18 F]flutemetamol amyloid positron emission tomography in preclinical and symptomatic Alzheimer's disease: Specific detection of advanced phases of amyloid‐β pathology
Thal, D. R., Beach, T. G., Zanette, M., Heurling, K., Chakrabarty, A., Ismail, A., Smith, A. P. L., & Buckley, C. (2015) · Alzheimer's & Dementia
Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments
Cited by 159
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Peripheral monocytes are functionally altered and invade the CNS in ALS patients
Zondler, L., Müller, K., Khalaji, S., Bliederhäuser, C., Ruf, W. P., Grozdanov, V., Thiemann, M., Fundel-Clemes, K., Freischmidt, A., Holzmann, K., et al. (2016) · Acta Neuropathologica
Amyotrophic Lateral Sclerosis ResearchNeuroinflammation and Neurodegeneration Mechanisms
Cited by 154
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Neurodegeneration in Normal Brain Aging and Disease
Thal, D. R., Del Tredici, K., & Braak, H. (2004) · Science of Aging Knowledge Environment
Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments
Cited by 149
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Different neuroinflammatory profile in amyotrophic lateral sclerosis and frontotemporal dementia is linked to the clinical phase
Oeckl, P., Weydt, P., Steinacker, P., Anderl-Straub, S., Nordin, F., Volk, A. E., Diehl-Schmid, J., Andersen, P. M., Kornhuber, J., Danek, A., et al. (2019) · Journal of Neurology, Neurosurgery & Psychiatry
Amyotrophic Lateral Sclerosis ResearchNeuroinflammation and Neurodegeneration Mechanisms
Cited by 139
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Capillary cerebral amyloid angiopathy is associated with vessel occlusion and cerebral blood flow disturbances
Thal, D. R., Capetillo-Zarate, E., Larionov, S., Staufenbiel, M., Zurbruegg, S., & Beckmann, N. (2009) · Neurobiology of Aging
Alzheimer's disease research and treatmentsIntracerebral and Subarachnoid Hemorrhage Research
Cited by 138
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Amyloid β-protein (Aβ)-containing astrocytes are located preferentially near N-terminal-truncated Aβ deposits in the human entorhinal cortex
Thal, D. R., Schultz, C., Dehghani, F., Yamaguchi, H., Braak, H., & Braak, E. (2000) · Acta Neuropathologica
Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms
Cited by 136
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Parenchymal and vascular Aβ‐deposition and its effects on the degeneration of neurons and cognition in Alzheimer's disease
Thal, D. R., Griffin, W. S. T., & Braak, H. (2008) · Journal of Cellular and Molecular Medicine
Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research
Cited by 134
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Aβ-induced acceleration of Alzheimer-related τ-pathology spreading and its association with prion protein
Gomes, L. A., Hipp, S. A., Rijal Upadhaya, A., Balakrishnan, K., Ospitalieri, S., Koper, M. J., Largo-Barrientos, P., Uytterhoeven, V., Reichwald, J., Rabe, S., et al. (2019) · Acta Neuropathologica
Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms
Cited by 125
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Interlaboratory Comparison of Assessments of Alzheimer Disease-Related Lesions: A Study of the BrainNet Europe Consortium
Alafuzoff, I., Pikkarainen, M., Al-Sarraj, S., Arzberger, T., Bell, J., Bodi, I., Bogdanovic, N., Budka, H., Bugiani, O., Ferrer, I., et al. (2006) · Journal of Neuropathology & Experimental Neurology
Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research
Cited by 117
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Gender and age modify the association between APOE and AD-related neuropathology
Ghebremedhin, E., Schultz, C., Thal, D. R., Rüb, U., Ohm, T. G., Braak, E., & Braak, H. (2001) · Neurology
Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research
Cited by 108
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Telomere shortening reduces Alzheimer’s disease amyloid pathology in mice
Rolyan, H., Scheffold, A., Heinrich, A., Begus-Nahrmann, Y., Langkopf, B. H., Hölter, S. M., Vogt-Weisenhorn, D. M., Liss, B., Wurst, W., Lie, D. C., et al. (2011) · Brain
Alzheimer's disease research and treatmentsTelomeres, Telomerase, and Senescence
Cited by 106
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Capillary cerebral amyloid angiopathy identifies a distinct APOE ε4-associated subtype of sporadic Alzheimer’s disease
Thal, D. R., Papassotiropoulos, A., Saido, T. C., Griffin, W. S. T., Mrak, R. E., Kölsch, H., Tredici, K. D., Attems, J., & Ghebremedhin, E. (2010) · Acta Neuropathologica
Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research
Cited by 103
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Spreading of amyloid, tau, and microvascular pathology in Alzheimer’s disease: Findings from neuropathological and neuroimaging studies.
Thal, D. R., Attems, J., & Ewers, M. (2014) · Journal of Alzheimer s Disease
Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments
Cited by 100
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Assessment of α-Synuclein Pathology: A Study of the BrainNet Europe Consortium
Alafuzoff, I., Parkkinen, L., Al-Sarraj, S., Arzberger, T., Bell, J., Bodi, I., Bogdanovic, N., Budka, H., Ferrer, I., Gelpi, E., et al. (2008) · Journal of Neuropathology & Experimental Neurology
Parkinson's Disease Mechanisms and TreatmentsDeep Brain Stimulation and Movement Disorders
Cited by 90
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GGA1 Is Expressed in the Human Brain and Affects the Generation of Amyloid β-Peptide
Wahle, T., Thal, D. R., Sastre, M., Rentmeister, A., Bogdanovic, N., Famulok, M., Heneka, M. T., & Walter, J. (2006) · The Journal of Neuroscience
Alzheimer's disease research and treatmentsCellular transport and secretion
Cited by 88
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Performance of [18F]flutemetamol amyloid imaging against the neuritic plaque component of CERAD and the current (2012) NIA‐AA recommendations for the neuropathologic diagnosis of Alzheimer's disease
Salloway, S., Gamez, J. E., Singh, U., Sadowsky, C. H., Villena, T., Sabbagh, M. N., Beach, T. G., Duara, R., Fleisher, A. S., Frey, K. A., et al. (2017) · Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring
Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments
Cited by 87
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Characteristics of Dyshoric Capillary Cerebral Amyloid Angiopathy
Richard, E., Carrano, A., Hoozemans, J. J., van Horssen, J., van Haastert, E. S., Eurelings, L. S., de Vries, H. E., Thal, D. R., Eikelenboom, P., van Gool, W. A., et al. (2010) · Journal of Neuropathology & Experimental Neurology
Intracerebral and Subarachnoid Hemorrhage ResearchAlzheimer's disease research and treatments
Cited by 71
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The impact of argyrophilic grain disease on the development of dementia and its relationship to concurrent Alzheimer's disease‐related pathology
Thal, D. R., Schultz, C., Botez, G., Del Tredici, K., Mrak, R. E., Griffin, W. S. T., Wiestler, O. D., Braak, H., & Ghebremedhin, E. (2005) · Neuropathology and Applied Neurobiology
Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research
Cited by 69
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Loss of γ-Secretase Function Impairs Endocytosis of Lipoprotein Particles and Membrane Cholesterol Homeostasis
Tamboli, I. Y., Prager, K., Thal, D. R., Thelen, K. M., Dewachter, I., Pietrzik, C. U., St. George-Hyslop, P., Sisodia, S. S., De Strooper, B., Heneka, M. T., et al. (2008) · The Journal of Neuroscience
Alzheimer's disease research and treatmentsCholesterol and Lipid Metabolism
Cited by 68
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Frontotemporal lobar degeneration FTLD-tau: preclinical lesions, vascular, and Alzheimer-related co-pathologies
Thal, D. R., von Arnim, C. A. F., Griffin, W. S. T., Mrak, R. E., Walker, L., Attems, J., & Arzberger, T. (2015) · Journal of Neural Transmission
Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research
Cited by 67
- Verified · note
The need to unify neuropathological assessments of vascular alterations in the ageing brain
Alafuzoff, I., Gelpi, E., Al-Sarraj, S., Arzberger, T., Attems, J., Bodi, I., Bogdanovic, N., Budka, H., Bugiani, O., Englund, E., et al. (2012) · Experimental Gerontology
Neurological Disease Mechanisms and TreatmentsDementia and Cognitive Impairment Research
Cited by 65
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