Loukas, Alex

Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookworm

Bethony, J., Brooker, S., Albonico, M., Geiger, S. M., Loukas, A., Diemert, D., & Hotez, P. J. (2006) · The Lancet

Parasites and Host InteractionsHelminth infection and control

Cited by 2,478

The intestinal microbiota contributes to the ability of helminths to modulate allergic inflammation

Zaiss, M. M., Rapin, A., Lebon, L., Dubey, L. K., Mosconi, I., Sarter, K., Piersigilli, A., Menin, L., Walker, A. W., Rougemont, J., et al. (2015) · Immunity

Parasites and Host InteractionsGut microbiota and health

Cited by 437

Hookworm secreted extracellular vesicles interact with host cells and prevent inducible colitis in mice

Eichenberger, R. M., Ryan, S., Jones, L., Buitrago, G., Polster, R., Montes de Oca, M., Zuvelek, J., Giacomin, P. R., Dent, L. A., Engwerda, C. R., et al. (2018) · Frontiers in Immunology

Parasites and Host InteractionsExtracellular vesicles in disease

Cited by 197

A granulin-like growth factor secreted by the carcinogenic liver fluke, Opisthorchis viverrini, promotes proliferation of host cells

Smout, M. J., Laha, T., Mulvenna, J., Sripa, B., Suttiprapa, S., Jones, A., Brindley, P. J., & Loukas, A. (2009) · PLoS Pathogens

Parasites and Host InteractionsCholangiocarcinoma and Gallbladder Cancer Studies

Cited by 187

A Multi-enzyme Cascade of Hemoglobin Proteolysis in the Intestine of Blood-feeding Hookworms

Williamson, A. L., Lecchi, P., Turk, B. E., Choe, Y., Hotez, P. J., McKerrow, J. H., Cantley, L. C., Sajid, M., Craik, C. S., & Loukas, A. (2004) · Journal of Biological Chemistry

Parasites and Host InteractionsHelminth infection and control

Cited by 181

Hookworm recombinant protein promotes regulatory T cell responses that suppress experimental asthma

Navarro, S., Pickering, D. A., Ferreira, I. B., Jones, L., Ryan, S., Troy, S., Leech, A., Hotez, P. J., Zhan, B., Laha, T., et al. (2016) · Science Translational Medicine

Parasites and Host InteractionsAsthma and respiratory diseases

Cited by 139

Carcinogenic parasite secretes growth factor that accelerates wound healing and potentially promotes neoplasia

Smout, M. J., Sotillo, J., Laha, T., Papatpremsiri, A., Rinaldi, G., Pimenta, R. N., Chan, L. Y., Johnson, M. S., Turnbull, L., Whitchurch, C. B., et al. (2015) · PLOS Pathogens

Parasites and Host InteractionsCholangiocarcinoma and Gallbladder Cancer Studies

Cited by 94

An enzymatically inactivated hemoglobinase from Necator americanus induces neutralizing antibodies against multiple hookworm species and protects dogs against heterologous hookworm infection

Pearson, M. S., Bethony, J. M., Pickering, D. A., de Oliveira, L. M., Jariwala, A., Santiago, H., Miles, A. P., Zhan, B., Jiang, D., Ranjit, N., et al. (2009) · The FASEB Journal

Parasites and Host InteractionsHelminth infection and control

Cited by 88

Immunological Responses to Envenomation

Ryan, R. Y. M., Seymour, J., Loukas, A., Lopez, J. A., Ikonomopoulou, M. P., & Miles, J. J. (2021) · Frontiers in Immunology

Venomous Animal Envenomation and StudiesFood Allergy and Anaphylaxis Research

Cited by 49

Probing of a human proteome microarray with a recombinant pathogen protein reveals a novel mechanism by which hookworms suppress B-cell receptor signaling

Tribolet, L., Cantacessi, C., Pickering, D. A., Navarro, S., Doolan, D. L., Trieu, A., Fei, H., Chao, Y., Hofmann, A., Gasser, R. B., et al. (2015) · Journal of Infectious Diseases

Parasites and Host InteractionsParasitic Diseases Research and Treatment

Cited by 48

A genome-wide analysis of annexins from parasitic organisms and their vectors

Cantacessi, C., Seddon, J. M., Miller, T. L., Leow, C. Y., Thomas, L., Mason, L., Willis, C., Walker, G., Loukas, A., Gasser, R. B., et al. (2013) · Scientific Reports

S100 Proteins and AnnexinsGenomics and Phylogenetic Studies

Cited by 46

Hookworm-Derived Metabolites Suppress Pathology in a Mouse Model of Colitis and Inhibit Secretion of Key Inflammatory Cytokines in Primary Human Leukocytes

Wangchuk, P., Shepherd, C., Constantinoiu, C., Ryan, R. Y. M., Kouremenos, K. A., Becker, L., Jones, L., Buitrago, G., Giacomin, P., Wilson, D., et al. (2019) · Infection and Immunity

Parasites and Host InteractionsInflammatory Bowel Disease

Cited by 42