Abascal, Federico

ProtTest: selection of best-fit models of protein evolution

Abascal, F., Zardoya, R., & Posada, D. (2005) · Bioinformatics

Genomics and Phylogenetic StudiesRNA and protein synthesis mechanisms

Cited by 3,063

Somatic mutant clones colonize the human esophagus with age

Martincorena, I., Fowler, J. C., Wabik, A., Lawson, A. R. J., Abascal, F., Hall, M. W. J., Cagan, A., Murai, K., Mahbubani, K., Stratton, M. R., et al. (2018) · Science

Cancer Genomics and DiagnosticsEsophageal Cancer Research and Treatment

Cited by 1,113

Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing

Cortés-Ciriano, I., Lee, J. J.-K., Xi, R., Jain, D., Jung, Y. L., Yang, L., Gordenin, D., Klimczak, L. J., Zhang, C.-Z., Pellman, D. S., et al. (2020) · Nature Genetics

Cancer Genomics and DiagnosticsGenomic variations and chromosomal abnormalities

Cited by 712

Somatic mutation rates scale with lifespan across mammals

Cagan, A., Baez-Ortega, A., Brzozowska, N., Abascal, F., Coorens, T. H. H., Sanders, M. A., Lawson, A. R. J., Harvey, L. M. R., Bhosle, S., Jones, D., et al. (2021) · Nature

Genetics, Aging, and Longevity in Model OrganismsCancer Genomics and Diagnostics

Cited by 482

Somatic mutation rates scale with lifespan across mammals

Cagan, A., Baez-Ortega, A., Brzozowska, N., Abascal, F., Coorens, T. H. H., Sanders, M. A., Lawson, A. R. J., Harvey, L. M. R., Bhosle, S., Jones, D., et al. (2022) · Nature

Genetics, Aging, and Longevity in Model OrganismsCancer Genomics and Diagnostics

Cited by 481

Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition

Rodriguez-Martin, B., Alvarez, E. G., Baez-Ortega, A., Zamora, J., Supek, F., Demeulemeester, J., Santamarina, M., Ju, Y. S., Temes, J., Garcia-Souto, D., et al. (2020) · Nature Genetics

Genomic variations and chromosomal abnormalitiesCancer Genomics and Diagnostics

Cited by 451

Somatic mutations and clonal dynamics in healthy and cirrhotic human liver

Brunner, S. F., Roberts, N. D., Wylie, L. A., Moore, L., Aitken, S. J., Davies, S. E., Sanders, M. A., Ellis, P., Alder, C., Hooks, Y., et al. (2019) · Nature

Cancer Genomics and DiagnosticsLiver physiology and pathology

Cited by 393

The longitudinal dynamics and natural history of clonal haematopoiesis

Fabre, M. A., de Almeida, J. G., Fiorillo, E., Mitchell, E., Damaskou, A., Rak, J., Orrù, V., Marongiu, M., Chapman, M. S., Vijayabaskar, M. S., et al. (2022) · Nature

Acute Myeloid Leukemia ResearchCancer Genomics and Diagnostics

Cited by 374

Extensive heterogeneity in somatic mutation and selection in the human bladder

Lawson, A. R. J., Abascal, F., Coorens, T. H. H., Hooks, Y., O’Neill, L., Latimer, C., Raine, K., Sanders, M. A., Warren, A. Y., Mahbubani, K. T. A., et al. (2020) · Science

Cancer Genomics and DiagnosticsBladder and Urothelial Cancer Treatments

Cited by 311

Disruption of chromatin folding domains by somatic genomic rearrangements in human cancer

Akdemir, K. C., Le, V. T., Chandran, S., Li, Y., Verhaak, R. G., Beroukhim, R., Campbell, P. J., Chin, L., Dixon, J. R., Futreal, P. A., et al. (2020) · Nature Genetics

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 283

Genomic landscape and chronological reconstruction of driver events in multiple myeloma

Maura, F., Bolli, N., Angelopoulos, N., Dawson, K. J., Leongamornlert, D., Martincorena, I., Mitchell, T. J., Fullam, A., Gonzalez, S., Szalat, R., et al. (2019) · Nature Communications

Multiple Myeloma Research and TreatmentsCancer Genomics and Diagnostics

Cited by 278

Convergent somatic mutations in metabolism genes in chronic liver disease

Ng, S. W. K., Rouhani, F. J., Brunner, S. F., Brzozowska, N., Aitken, S. J., Yang, M., Abascal, F., Moore, L., Nikitopoulou, E., Chappell, L., et al. (2021) · Nature

Cancer Genomics and DiagnosticsLiver Disease Diagnosis and Treatment

Cited by 190

Increased somatic mutation burdens in normal human cells due to defective DNA polymerases

Robinson, P. S., Coorens, T. H. H., Palles, C., Mitchell, E., Abascal, F., Olafsson, S., Lee, B. C. H., Lawson, A. R. J., Lee-Six, H., Moore, L., et al. (2021) · Nature Genetics

Cancer Genomics and DiagnosticsDNA Repair Mechanisms

Cited by 173

Whole-genome sequencing reveals progressive versus stable myeloma precursor conditions as two distinct entities

Oben, B., Froyen, G., Maclachlan, K. H., Leongamornlert, D., Abascal, F., Zheng-Lin, B., Yellapantula, V., Derkach, A., Geerdens, E., Diamond, B. T., et al. (2021) · Nature Communications

Multiple Myeloma Research and TreatmentsCancer Genomics and Diagnostics

Cited by 129