Cited by 330Asthma and respiratory diseasesGut microbiota and healthDermatology and Skin Diseases

The microbiome in allergic disease: Current understanding and future opportunities—2017 PRACTALL document of the American Academy of Allergy, Asthma & Immunology and the European Academy of Allergy and Clinical Immunology

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Huang, Yvonne J., Marsland, Benjamin J., Bunyavanich, Supinda, O'Mahony, Liam, Leung, Donald Y.M., Muraro, Antonella, Fleisher, Thomas A.·2017·Journal of Allergy and Clinical Immunology

Abstract

PRACTALL is a joint initiative of the American Academy of Allergy, Asthma & Immunology and the European Academy of Allergy and Clinical Immunology to provide shared evidence-based recommendations on cutting-edge topics in the field of allergy and immunology. PRACTALL 2017 is focused on what has been established regarding the role of the microbiome in patients with asthma, atopic dermatitis, and food allergy. This is complemented by outlining important knowledge gaps regarding its role in allergic disease and delineating strategies necessary to fill these gaps. In addition, a review of progress in approaches used to manipulate the microbiome will be addressed, identifying what has and has not worked to serve as a baseline for future directions to intervene in allergic disease development, progression, or both.

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  • Oral probiotics may counteract UV damage and relieve inflammatory dermatoses by regulating immune-related signal pathways.

    “Oral probiotics may counteract UV damage [80] and relieve inflammatory dermatoses [81] by regulating immune-related signal pathways.”

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Authors
Huang, Y. J., Marsland, B. J., Bunyavanich, S., O'Mahony, L., Leung, D. Y. M., Muraro, A., & Fleisher, T. A.
Affiliations
  • University of Michigan (US)
  • University of Lausanne (CH)
  • Icahn School of Medicine at Mount Sinai (US)
  • National Jewish Health (US)
  • Azienda Ospedale - Università Padova (IT)
  • National Institutes of Health (US)
Corresponding author
Fleisher, Thomas A.
Venue
Journal of Allergy and Clinical Immunology
Publisher
Elsevier BV
Published
2017-04
Volume
139
Issue
4
Pages
1099-1110
ISSN
0091-6749 (ISSN-L)
OpenAlex
W2594112302
Cited by
330
References
120
Citations by year
2026: 14 · 2025: 28 · 2024: 27 · 2023: 27 · 2022: 46 · 2021: 52 · 2020: 44 · 2019: 37 · 2018: 40 · 2017: 15
FWCI
4.56
Type
journal article
Language
en
Open access
Locations
  • Journal of Allergy and Clinical Immunology (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
  • IRIS (submittedVersion)
  • SERVAL (Université de Lausanne) (submittedVersion)
  • Zurich Open Repository and Archive (University of Zurich) (submittedVersion)
Funders
  • National Heart, Lung, and Blood Institute (K23HL105572)
  • National Institute of Allergy and Infectious Diseases (R01AI118833)
Topics
  • Health Sciences › Medicine › Physiology › Asthma and respiratory diseases
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
  • Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
Keywords
microbiome, allergic diseases, asthma, atopic dermatitis, food allergy, microbiome manipulation, probiotics, prebiotics, evidence-based recommendations, knowledge gaps
MeSH terms
Allergy and Immunology, Animals, Humans, Hypersensitivity, Microbiota

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