Chiu, Isaac M.

Bacteria activate sensory neurons that modulate pain and inflammation

Chiu, I. M., Heesters, B. A., Ghasemlou, N., Von Hehn, C. A., Zhao, F., Tran, J., Wainger, B., Strominger, A., Muralidharan, S., Horswill, A. R., et al. (2013) · Nature

Pain Mechanisms and TreatmentsIon Channels and Receptors

Cited by 949

Neurogenic inflammation and the peripheral nervous system in host defense and immunopathology

Chiu, I. M., von Hehn, C. A., & Woolf, C. J. (2012) · Nature Neuroscience

Pain Mechanisms and TreatmentsVagus Nerve Stimulation Research

Cited by 686

A Neurodegeneration-Specific Gene-Expression Signature of Acutely Isolated Microglia from an Amyotrophic Lateral Sclerosis Mouse Model

Chiu, I. M., Morimoto, E. T. A., Goodarzi, H., Liao, J. T., O’Keeffe, S., Phatnani, H. P., Muratet, M., Carroll, M. C., Levy, S., Tavazoie, S., et al. (2013) · Cell Reports

Neuroinflammation and Neurodegeneration MechanismsAmyotrophic Lateral Sclerosis Research

Cited by 651

Gut-licensed IFNγ+ NK cells drive LAMP1+TRAIL+ anti-inflammatory astrocytes

Sanmarco, L. M., Wheeler, M. A., Gutiérrez-Vázquez, C., Polonio, C. M., Linnerbauer, M., Pinho-Ribeiro, F. A., Li, Z., Giovannoni, F., Batterman, K. V., Scalisi, G., et al. (2021) · Nature

Neuroinflammation and Neurodegeneration Mechanismsinterferon and immune responses

Cited by 331

An intestinal organ culture system uncovers a role for the nervous system in microbe-immune crosstalk

Yissachar, N., Zhou, Y., Ung, L., Lai, N. Y., Mohan, J. F., Ehrlicher, A., Weitz, D. A., Kasper, D. L., Chiu, I. M., Mathis, D., et al. (2017) · Cell

Gut microbiota and healthGastrointestinal motility and disorders

Cited by 242

Targeted delivery of siRNA to macrophages for anti-inflammatory treatment.

Kim, S.-S., Ye, C., Kumar, P., Chiu, I., Subramanya, S., Wu, H., Shankar, P., & Manjunath, N. (2010) · Molecular Therapy

RNA Interference and Gene DeliveryNeuroinflammation and Neurodegeneration Mechanisms

Cited by 176

Interleukin-6 produced by enteric neurons regulates the number and phenotype of microbe-responsive regulatory T cells in the gut

Yan, Y., Ramanan, D., Rozenberg, M., McGovern, K., Rastelli, D., Vijaykumar, B., Yaghi, O., Voisin, T., Mosaheb, M., Chiu, I., et al. (2021) · Immunity

T-cell and B-cell ImmunologyGastrointestinal motility and disorders

Cited by 165

An airway-to-brain sensory pathway mediates influenza-induced sickness

Bin, N.-R., Prescott, S. L., Horio, N., Wang, Y., Chiu, I. M., & Liberles, S. D. (2023) · Nature

Pain Mechanisms and TreatmentsVagus Nerve Stimulation Research

Cited by 111

Molecular basis for shifted receptor recognition by an encephalitic arbovirus

Fan, X., Li, W., Oros, J., Plante, J. A., Mitchell, B. M., Plung, J. S., Basu, H., Nagappan-Chettiar, S., Boeckers, J. M., Tjang, L. V., et al. (2025) · Cell

Mosquito-borne diseases and controlViral Infections and Vectors

Cited by 17