Targeted delivery of siRNA to macrophages for anti-inflammatory treatment.
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RVG peptide targets the alpha-7-subunit of the nicotinic acetylcholine receptor and facilitates transcytosis of EVs across the blood-brain barrier, with specific targeting of neural cells in the brain.
“RVG peptide is known to target the alpha-7-subunit of the nicotinic acetylcholine receptor (Kim et al., 2010), and facilitates the transcytosis of the EVs across the blood-brain barrier, with specific targeting of neural cells in the brain (Loddo et al., 1966; Alvarez-Erviti et al., 2011).”
From Engineered Extracellular Vesicles Loaded With miR-124 Attenuate Cocaine-Mediated Activation of Microglia (2020) · cites this paper as Kim et al., 2010
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Cites
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McGeer, E. G., Klegeris, A., & McGeer, P. L. (2005) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2005.08.008 · Cited by 170 · see citing works
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György, B., Fitzpatrick, Z., Crommentuijn, M. H. W., Mu, D., & Maguire, C. A. (2014) · Biomaterials · doi:10.1016/j.biomaterials.2014.05.032 · Cited by 153 · see citing works
Yadav, S., Gandham, S. K., Panicucci, R., & Amiji, M. M. (2016) · Nanomedicine: Nanotechnology, Biology and Medicine · doi:10.1016/j.nano.2015.12.374 · Cited by 125 · see citing works
Chivero, E. T., Liao, K., Niu, F., Tripathi, A., Tian, C., Buch, S., & Hu, G. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.00573 · Cited by 69 · see citing works
Fu, C., Xiang, Y., Li, X., & Fu, A. (2018) · Materials Science and Engineering: C · doi:10.1016/j.msec.2017.12.029 · Cited by 48 · see citing works
- Authors
- Kim, S.-S., Ye, C., Kumar, P., Chiu, I., Subramanya, S., Wu, H., Shankar, P., & Manjunath, N.
- Venue
- Molecular Therapy
- Publisher
- Elsevier BV
- Published
- 2010-05
- Volume
- 18
- Issue
- 5
- Pages
- 993-1001
- ISSN
- 1525-0016
- Cited by
- 164
- References
- 4
- Language
- en
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