Cited by 164

Targeted delivery of siRNA to macrophages for anti-inflammatory treatment.

Kim, Sang-Soo, Ye, Chunting, Kumar, Priti, Chiu, Isaac, Subramanya, Sandesh, Wu, Haoquan, Shankar, Premlata, Manjunath, N·2010·Molecular Therapy

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1038/mt.2010.27

Cites

4 of 4 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • RVG peptide targets the alpha-7-subunit of the nicotinic acetylcholine receptor and facilitates transcytosis of EVs across the blood-brain barrier, with specific targeting of neural cells in the brain.

    “RVG peptide is known to target the alpha-7-subunit of the nicotinic acetylcholine receptor (Kim et al., 2010), and facilitates the transcytosis of the EVs across the blood-brain barrier, with specific targeting of neural cells in the brain (Loddo et al., 1966; Alvarez-Erviti et al., 2011).”

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

Research works printed but not linked: 25

  1. [1]1. Jahoor, A ∙ Patel, R ∙ Bryan, A ... Peroxisome proliferator-activated receptors mediate host cell proinflammatory responses to Pseudomonas aeruginosa autoinducer J Bacteriol. 2008; 190:4408-4415 Crossref Scopus (122) PubMed Google Scholar
  2. [2]2. Liu, J ∙ Liu, Y ∙ Zhang, H ... KLF4 promotes the expression, translocation, and releas eof HMGB1 in RAW264.7 macrophages in response to LPS Shock. 2008; 30:260-266 PubMed Google Scholar
  3. [3]3. Czapski, GA ∙ Cakala, M ∙ Chalimoniuk, M ... Role of nitric oxide in the brain during lipopolysaccharide-evoked systemic inflammation J Neurosci Res. 2007; 85:1694-1703 Crossref Scopus (70) PubMed Google Scholar
  4. [4]4. Perry, VH ∙ Newman, TA ∙ Cunningham, C The impact of systemic infection on the progression of neurodegenerative disease Nat Rev Neurosci. 2003; 4:103-112 Crossref Scopus (355) PubMed Google Scholar
  5. [8]8. Polazzi, E ∙ Contestabile, A Reciprocal interactions between microglia and neurons: from survival to neuropathology Rev Neurosci. 2002; 13:221-242 Crossref Scopus (196) PubMed Google Scholar
  6. [9]9. Layé, S ∙ Parnet, P ∙ Goujon, E ... Peripheral administration of lipopolysaccharide induces the expression of cytokine transcripts in the brain and pituitary of mice Brain Res Mol Brain Res. 1994; 27:157-162 Crossref Scopus (455) PubMed Google Scholar
  7. [10]10. Pitossi, F ∙ del Rey, A ∙ Kabiersch, A ... Induction of cytokine transcripts in the central nervous system and pituitary following peripheral administration of endotoxin to mice J Neurosci Res. 1997; 48:287-298 Crossref Scopus (169) PubMed Google Scholar
  8. [11]11. Sawada, M ∙ Kondo, N ∙ Suzumura, A ... Production of tumor necrosis factor-α by microglia and astrocytes in culture Brain Res. 1989; 491:394-397 Crossref Scopus (589) PubMed Google Scholar
  9. [12]12. Rivest, S ∙ Lacroix, S ∙ Vallières, L ... How the blood talks to the brain parenchyma and the paraventricular nucleus of the hypothalamus during systemic inflammatory and infectious stimuli Proc Soc Exp Biol Med. 2000; 223:22-38 Crossref Scopus (250) PubMed Google Scholar
  10. [14]14. McCoy, MK ∙ Tansey, MG TNF signaling inhibition in the CNS: implications for normal brain function and neurodegenerative disease J Neuroinflammation. 2008; 5:45 Crossref Scopus (686) PubMed Google Scholar
  11. [15]15. Lin, J ∙ Ziring, D ∙ Desai, S ... TNFα blockade in human diseases: an overview of efficacy and safety Clin Immunol. 2008; 126:13-30 Crossref Scopus (237) PubMed Google Scholar
  12. [16]16. Kirman, I ∙ Whelan, RL ∙ Nielsen, OH Infliximab: mechanism of action beyond TNF-α neutralization in inflammatory bowel disease Eur J Gastroenterol Hepatol. 2004; 16:639-641 Crossref Scopus (42) PubMed Google Scholar
  13. [17]17. Charles, P ∙ Elliott, MJ ∙ Davis, D ... Regulation of cytokines, cytokine inhibitors, and acute-phase proteins following anti-TNF-α therapy in rheumatoid arthritis J Immunol. 1999; 163:1521-1528 Crossref PubMed Google Scholar
  14. [18]18. Howard, KA ∙ Paludan, SR ∙ Behlke, MA ... Chitosan/siRNA nanoparticle-mediated TNF-α knockdown in peritoneal macrophages for anti-inflammatory treatment in a murine arthritis model Mol Ther. 2009; 17:162-168 Full Text Full Text (PDF) Scopus (261) PubMed Google Scholar
  15. [19]19. Khoury, M ∙ Louis-Plence, P ∙ Escriou, V ... Efficient new cationic liposome formulation for systemic delivery of small interfering RNA silencing tumor necrosis factor α in experimental arthritis Arthritis Rheum. 2006; 54:1867-1877 Crossref Scopus (177) PubMed Google Scholar
  16. [20]20. Peng, X ∙ Tao, K ∙ Cheng, T ... Efficient Inhibition of wear debris-induced inflammation by locally delivered siRNA Biochem Biophys Res Commun. 2008; 377:532-537 Crossref Scopus (23) PubMed Google Scholar
  17. [21]21. Inoue, A ∙ Takahashi, KA ∙ Mazda, O ... Comparison of anti-rheumatic effects of local RNAi-based therapy in collagen induced arthritis rats using various cytokine genes as molecular targets Mod Rheumatol. 2009; 19:125-133 Crossref PubMed Google Scholar
  18. [22]22. Kumar, P ∙ Wu, H ∙ McBride, JL ... Transvascular delivery of small interfering RNA to the central nervous system Nature. 2007; 448:39-43 Crossref Scopus (1106) PubMed Google Scholar
  19. [24]24. Boado, RJ Blood-brain barrier transport of non-viral gene and RNAi therapeutics Pharm Res. 2007; 24:1772-1787 Crossref Scopus (84) PubMed Google Scholar
  20. [25]25. Shytle, RD ∙ Mori, T ∙ Townsend, K ... Cholinergic modulation of microglial activation by α7 nicotinic receptors J Neurochem. 2004; 89:337-343 Crossref Scopus (527) PubMed Google Scholar
  21. [26]26. Castanotto, D ∙ Rossi, JJ The promises and pitfalls of RNA-interference-based therapeutics Nature. 2009; 457:426-433 Crossref Scopus (1100) PubMed Google Scholar
  22. [27]27. Sørensen, DR ∙ Leirdal, M ∙ Sioud, M Gene silencing by systemic delivery of synthetic siRNAs in adult mice J Mol Biol. 2003; 327:761-766 Crossref Scopus (439) PubMed Google Scholar
  23. [28]28. Lundberg, P ∙ Welander, PV ∙ Edwards, 3rd, CK ... Tumor necrosis factor (TNF) protects resistant C57BL/6 mice against herpes simplex virus-induced encephalitis independently of signaling via TNF receptor 1 or 2 J Virol. 2007; 81:1451-1460 Crossref Scopus (62) PubMed Google Scholar
  24. [29]29. Akhtar, S ∙ Benter, IF Nonviral delivery of synthetic siRNAs in vivo J Clin Invest. 2007; 117:3623-3632 Crossref Scopus (431) PubMed Google Scholar
  25. [30]30. Misko, TP ∙ Trotter, JL ∙ Cross, AH Mediation of inflammation by encephalitogenic cells: interferon gamma induction of nitric oxide synthase and cyclooxygenase 2 J Neuroimmunol. 1995; 61:195-204

Cited by

Sorted by citations

Authors
Kim, S.-S., Ye, C., Kumar, P., Chiu, I., Subramanya, S., Wu, H., Shankar, P., & Manjunath, N.
Venue
Molecular Therapy
Publisher
Elsevier BV
Published
2010-05
Volume
18
Issue
5
Pages
993-1001
ISSN
1525-0016
Cited by
164
References
4
Language
en

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review