Shulman, Gerald I.

Gene knockout of Acc2 has little effect on body weight, fat mass, or food intake

Olson, D. P., Pulinilkunnil, T., Cline, G. W., Shulman, G. I., & Lowell, B. B. (2010) · Proceedings of the National Academy of Sciences

Cancer, Lipids, and MetabolismRegulation of Appetite and Obesity

Cited by 109

TFAM Enhances Fat Oxidation and Attenuates High-Fat Diet–Induced Insulin Resistance in Skeletal Muscle

Koh, J.-H., Johnson, M. L., Dasari, S., LeBrasseur, N. K., Vuckovic, I., Henderson, G. C., Cooper, S. A., Manjunatha, S., Ruegsegger, G. N., Shulman, G. I., et al. (2019) · Diabetes

Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism

Cited by 92

Hepatic Insulin Resistance Is Not Pathway Selective in Humans With Nonalcoholic Fatty Liver Disease

ter Horst, K. W., Vatner, D. F., Zhang, D., Cline, G. W., Ackermans, M. T., Nederveen, A. J., Verheij, J., Demirkiran, A., van Wagensveld, B. A., Dallinga-Thie, G. M., et al. (2021) · Diabetes Care

Liver Disease Diagnosis and TreatmentDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 88

New insights into the pathogenesis of insulin resistance in humans using magnetic resonance spectroscopy

Petersen, K. F., & Shulman, G. I. (2006) · Obesity

Diabetes, Cardiovascular Risks, and LipoproteinsAdvanced MRI Techniques and Applications

Cited by 87

Pioglitazone Improves Insulin Sensitivity Among Nondiabetic Patients With a Recent Transient Ischemic Attack or Ischemic Stroke

Kernan, W. N., Inzucchi, S. E., Viscoli, C. M., Brass, L. M., Bravata, D. M., Shulman, G. I., McVeety, J. C., & Horwitz, R. I. (2003) · Stroke

Diabetes, Cardiovascular Risks, and LipoproteinsDiabetes Treatment and Management

Cited by 84

Propionate increases hepatic pyruvate cycling and anaplerosis and alters mitochondrial metabolism

Perry, R. J., Borders, C. B., Cline, G. W., Zhang, X.-M., Alves, T. C., Petersen, K. F., Rothman, D. L., Kibbey, R. G., & Shulman, G. I. (2016) · Journal of Biological Chemistry

Metabolism, Diabetes, and CancerMetabolomics and Mass Spectrometry Studies

Cited by 78

Anti-inflammatory effects of oestrogen mediate the sexual dimorphic response to lipid-induced insulin resistance

Camporez, J. P., Lyu, K., Goldberg, E. L., Zhang, D., Cline, G. W., Jurczak, M. J., Dixit, V. D., Petersen, K. F., & Shulman, G. I. (2019) · The Journal of Physiology

Adipokines, Inflammation, and Metabolic DiseasesEstrogen and related hormone effects

Cited by 71

Paradoxical coupling of triglyceride synthesis and fatty acid oxidation in skeletal muscle overexpressing DGAT1

Liu, L., Shi, X., Choi, C. S., Shulman, G. I., Klaus, K., Nair, K. S., Schwartz, G. J., Zhang, Y., Goldberg, I. J., & Yu, Y.-H. (2009) · Diabetes

Adipose Tissue and MetabolismLipid metabolism and biosynthesis

Cited by 66

Mitochondrial-Targeted Catalase Protects Against High-Fat Diet–Induced Muscle Insulin Resistance by Decreasing Intramuscular Lipid Accumulation

Lee, H.-Y., Lee, J. S., Alves, T., Ladiges, W., Rabinovitch, P. S., Jurczak, M. J., Choi, C. S., Shulman, G. I., & Samuel, V. T. (2017) · Diabetes

Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism

Cited by 66

Glycerol-3-Phosphate Acyltransferase 1 Deficiency in ob/ob Mice Diminishes Hepatic Steatosis but Does Not Protect Against Insulin Resistance or Obesity

Wendel, A. A., Li, L. O., Li, Y., Cline, G. W., Shulman, G. I., & Coleman, R. A. (2010) · Diabetes

Liver Disease Diagnosis and TreatmentLipid metabolism and biosynthesis

Cited by 63

Mechanism of glucose intolerance in mice with dominant negative mutation of CEACAM1

Park, S.-Y., Cho, Y.-R., Kim, H.-J., Hong, E.-G., Higashimori, T., Lee, S. J., Goldberg, I. J., Shulman, G. I., Najjar, S. M., & Kim, J. K. (2006) · American Journal of Physiology-Endocrinology and Metabolism

Metabolism, Diabetes, and CancerAdipokines, Inflammation, and Metabolic Diseases

Cited by 51

Liver lipid droplet cholesterol content is a key determinant of metabolic dysfunction–associated steatohepatitis

Sakuma, I., Gaspar, R. C., Nasiri, A. R., Dufour, S., Kahn, M., Zheng, J., LaMoia, T. E., Guerra, M. T., Taki, Y., Kawashima, Y., et al. (2025) · Proceedings of the National Academy of Sciences

Liver Disease Diagnosis and TreatmentCholesterol and Lipid Metabolism

Cited by 46

A feed-forward regulatory loop in adipose tissue promotes signaling by the hepatokine FGF21

Han, M. S., Perry, R. J., Camporez, J.-P., Scherer, P. E., Shulman, G. I., Gao, G., & Davis, R. J. (2021) · Genes & Development

Fibroblast Growth Factor ResearchAdipokines, Inflammation, and Metabolic Diseases

Cited by 43

A controlled-release mitochondrial protonophore reverses hypertriglyceridemia, nonalcoholic steatohepatitis, and diabetes in lipodystrophic mice

Abulizi, A., Perry, R. J., Camporez, J. P. G., Jurczak, M. J., Petersen, K. F., Aspichueta, P., & Shulman, G. I. (2017) · The FASEB Journal

Liver Disease Diagnosis and TreatmentAdipose Tissue and Metabolism

Cited by 41

Reduced heart size and increased myocardial fuel substrate oxidation in ACC2 mutant mice

Essop, M. F., Camp, H. S., Choi, C. S., Sharma, S., Fryer, R. M., Reinhart, G. A., Guthrie, P. H., Bentebibel, A., Gu, Z., Shulman, G. I., et al. (2008) · American Journal of Physiology-Heart and Circulatory Physiology

Cardiovascular Function and Risk FactorsCancer, Lipids, and Metabolism

Cited by 40

Hepatocyte CYR61 polarizes profibrotic macrophages to orchestrate NASH fibrosis

Mooring, M., Yeung, G. A., Luukkonen, P., Liu, S., Akbar, M. W., Zhang, G. J., Balogun, O., Yu, X., Mo, R., Nejak-Bowen, K., et al. (2023) · Science Translational Medicine

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 33

Progesterone administration induced impairment of insulin suppression of hepatic glucose production

Nelson, T., Shulman, G., Grainger, D., & Diamond, M. P. (1994) · Fertility and Sterility

Pancreatic function and diabetesEstrogen and related hormone effects

Cited by 16