Barres, Ben A.

Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson’s disease

Yun, S. P., Kam, T.-I., Panicker, N., Kim, S., Oh, Y., Park, J.-S., Kwon, S.-H., Park, Y. J., Karuppagounder, S. S., Park, H., et al. (2018) · Nature Medicine

Neuroinflammation and Neurodegeneration MechanismsParkinson's Disease Mechanisms and Treatments

Cited by 1,123

The Complement System: An Unexpected Role in Synaptic Pruning During Development and Disease

Stephan, A. H., Barres, B. A., & Stevens, B. (2012) · Annual Review of Neuroscience

Complement system in diseasesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 1,113

Emerging roles of astrocytes in neural circuit development

Clarke, L. E., & Barres, B. A. (2013) · Nature Reviews Neuroscience

Neuroscience and Neuropharmacology ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 975

Gabapentin Receptor α2δ-1 Is a Neuronal Thrombospondin Receptor Responsible for Excitatory CNS Synaptogenesis

Eroglu, Ç., Allen, N. J., Susman, M. W., O'Rourke, N. A., Park, C. Y., Özkan, E., Chakraborty, C., Mulinyawe, S. B., Annis, D. S., Huberman, A. D., et al. (2009) · Cell

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 893

Glia — more than just brain glue

Allen, N. J., & Barres, B. A. (2009) · Nature

Neuroinflammation and Neurodegeneration MechanismsNeuroscience and Neuropharmacology Research

Cited by 856

Microglia: Scapegoat, saboteur, or something else?

Aguzzi, A., Barres, B. A., & Bennett, M. L. (2013) · Science

Neuroinflammation and Neurodegeneration MechanismsNeurological Disease Mechanisms and Treatments

Cited by 836

Regulation of synaptic connectivity by glia.

Eroglu, C., & Barres, B. A. (2010) · Nature

Neuroscience and Neuropharmacology ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 813

Astrocyte glypicans 4 and 6 promote formation of excitatory synapses via GluA1 AMPA receptors

Allen, N. J., Bennett, M. L., Foo, L. C., Wang, G. X., Chakraborty, C., Smith, S. J., & Barres, B. A. (2012) · Nature

Neuroscience and Neuropharmacology ResearchProteoglycans and glycosaminoglycans research

Cited by 764

Wnt/β-catenin signaling is required for CNS, but not non-CNS, angiogenesis

Daneman, R., Agalliu, D., Zhou, L., Kuhnert, F., Kuo, C. J., & Barres, B. A. (2009) · Proceedings of the National Academy of Sciences

Barrier Structure and Function StudiesAngiogenesis and VEGF in Cancer

Cited by 753

Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation

Lui, H., Zhang, J., Makinson, S. R., Cahill, M. K., Kelley, K. W., Huang, H.-Y., Shang, Y., Oldham, M. C., Martens, L. H., Gao, F., et al. (2016) · Cell

Neuroinflammation and Neurodegeneration MechanismsAmyotrophic Lateral Sclerosis Research

Cited by 729

Multiple extracellular signals are required for long-term oligodendrocyte survival

Barres, B. A., Schmid, R., Sendnter, M., & Raff, M. C. (1993) · Development

Neurogenesis and neuroplasticity mechanismsNerve injury and regeneration

Cited by 712

Stepwise Recruitment of Transcellular and Paracellular Pathways Underlies Blood-Brain Barrier Breakdown in Stroke

Knowland, D., Arac, A., Sekiguchi, K. J., Hsu, M., Lutz, S. E., Perrino, J., Steinberg, G. K., Barres, B. A., Nimmerjahn, A., & Agalliu, D. (2014) · Neuron

Barrier Structure and Function StudiesDrug Transport and Resistance Mechanisms

Cited by 703

Astrocytes and disease: a neurodevelopmental perspective

Molofsky, A. V., Krenick, R., Ullian, E., Tsai, H.-H., Deneen, B., Richardson, W. D., Barres, B. A., & Rowitch, D. H. (2012) · Genes & Development

Genetics and Neurodevelopmental DisordersNeurogenesis and neuroplasticity mechanisms

Cited by 682

Proliferation of oligodendrocyte precursor cells depends on electrical activity in axons

Barres, B. A., & Raff, M. C. (1993) · Nature

Neurogenesis and neuroplasticity mechanismsMultiple Sclerosis Research Studies

Cited by 673

Ageing hallmarks exhibit organ-specific temporal signatures

Schaum, N., Lehallier, B., Hahn, O., Pálovics, R., Hosseinzadeh, S., Lee, S. E., Sit, R., Lee, D. P., Losada, P. M., Zardeneta, M. E., et al. (2020) · Nature

Genetics, Aging, and Longevity in Model OrganismsSingle-cell and spatial transcriptomics

Cited by 671

Diverse Requirements for Microglial Survival, Specification, and Function Revealed by Defined-Medium Cultures

Bohlen, C. J., Bennett, F. C., Tucker, A. F., Collins, H. Y., Mulinyawe, S. B., & Barres, B. A. (2017) · Neuron

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 658

Astrocyte-derived interleukin-33 promotes microglial synapse engulfment and neural circuit development

Vainchtein, I. D., Chin, G., Cho, F. S., Kelley, K. W., Miller, J. G., Chien, E. C., Liddelow, S. A., Nguyen, P. T., Nakao-Inoue, H., Dorman, L. C., et al. (2018) · Science

Neuroinflammation and Neurodegeneration MechanismsIL-33, ST2, and ILC Pathways

Cited by 657

Control of excitatory CNS synaptogenesis by astrocyte-secreted proteins Hevin and SPARC

Kucukdereli, H., Allen, N. J., Lee, A. T., Feng, A., Ozlu, M. I., Conatser, L. M., Chakraborty, C., Workman, G., Weaver, M., Sage, E. H., et al. (2011) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 642

Human Astrocyte Maturation Captured in 3D Cerebral Cortical Spheroids Derived from Pluripotent Stem Cells

Sloan, S. A., Darmanis, S., Huber, N., Khan, T. A., Birey, F., Caneda, C., Reimer, R., Quake, S. R., Barres, B. A., & Paşca, S. P. (2017) · Neuron

Pluripotent Stem Cells ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 593

Neurotoxic reactive astrocytes induce cell death via saturated lipids

Guttenplan, K. A., Weigel, M. K., Prakash, P., Wijewardhane, P. R., Hasel, P., Rufen-Blanchette, U., Münch, A. E., Blum, J. A., Fine, J., Neal, M. C., et al. (2021) · Nature

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 578

Dicer1 and miR-219 Are Required for Normal Oligodendrocyte Differentiation and Myelination

Dugas, J. C., Cuellar, T. L., Scholze, A., Ason, B., Ibrahim, A., Emery, B., Zamanian, J. L., Foo, L. C., McManus, M. T., & Barres, B. A. (2010) · Neuron

Neurogenesis and neuroplasticity mechanismsMicroRNA in disease regulation

Cited by 577

The Mouse Blood-Brain Barrier Transcriptome: A New Resource for Understanding the Development and Function of Brain Endothelial Cells

Daneman, R., Zhou, L., Agalliu, D., Cahoy, J. D., Kaushal, A., & Barres, B. A. (2010) · PLoS ONE

Barrier Structure and Function StudiesDrug Transport and Resistance Mechanisms

Cited by 577

Myelin gene regulatory factor is a critical transcriptional regulator required for CNS myelination

Emery, B., Agalliu, D., Cahoy, J. D., Watkins, T. A., Dugas, J. C., Mulinyawe, S. B., Ibrahim, A., Ligon, K. L., Rowitch, D. H., & Barres, B. A. (2009) · Cell

Neurogenesis and neuroplasticity mechanismsMultiple Sclerosis Research Studies

Cited by 559

A combination of ontogeny and CNS environment establishes microglial identity

Bennett, F. C., Bennett, M. L., Yaqoob, F., Mulinyawe, S. B., Grant, G. A., Hayden Gephart, M., Plowey, E. D., & Barres, B. A. (2018) · Neuron

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 524