Teichmann, Sarah A.

Impact of the Human Cell Atlas on medicine

Rood, J. E., Maartens, A., Hupalowska, A., Teichmann, S. A., & Regev, A. (2022) · Nature Medicine

Single-cell and spatial transcriptomicsBioinformatics and Genomic Networks

Cited by 222

Gene expression variability across cells and species shapes innate immunity

Hagai, T., Chen, X., Miragaia, R. J., Rostom, R., Gomes, T., Kunowska, N., Henriksson, J., Park, J.-E., Proserpio, V., Donati, G., et al. (2018) · Nature

Immune Response and InflammationGenomics and Chromatin Dynamics

Cited by 220

A spatially resolved atlas of the human lung characterizes a gland-associated immune niche

Madissoon, E., Oliver, A. J., Kleshchevnikov, V., Wilbrey-Clark, A., Polanski, K., Richoz, N., Ribeiro Orsi, A., Mamanova, L., Bolt, L., Elmentaite, R., et al. (2023) · Nature Genetics

Single-cell and spatial transcriptomicsAsthma and respiratory diseases

Cited by 219

Human skeletal muscle aging atlas

Kedlian, V. R., Wang, Y., Liu, T., Chen, X., Bolt, L., Tudor, C., Shen, Z., Fasouli, E. S., Prigmore, E., Kleshchevnikov, V., et al. (2024) · Nature Aging

Muscle Physiology and DisordersSingle-cell and spatial transcriptomics

Cited by 218

Computational methods for single-cell omics across modalities

Efremova, M., & Teichmann, S. A. (2020) · Nature Methods

Single-cell and spatial transcriptomicsBioinformatics and Genomic Networks

Cited by 201

Single-Cell RNA-Sequencing Reveals a Continuous Spectrum of Differentiation in Hematopoietic Cells

Macaulay, I. C., Svensson, V., Labalette, C., Ferreira, L., Hamey, F., Voet, T., Teichmann, S. A., & Cvejic, A. (2016) · Cell Reports

Single-cell and spatial transcriptomicsDevelopmental Biology and Gene Regulation

Cited by 191

The organoid cell atlas

the Human Cell Atlas ‘Biological Network’ Organoids, Bock, C., Boutros, M., Camp, J. G., Clarke, L., Clevers, H., Knoblich, J. A., Liberali, P., Regev, A., Rios, A. C., et al. (2021) · Nature Biotechnology

Single-cell and spatial transcriptomicsPluripotent Stem Cells Research

Cited by 171

Single-cell atlas of human liver development reveals pathways directing hepatic cell fates

Wesley, B. T., Ross, A. D. B., Muraro, D., Miao, Z., Saxton, S., Tomaz, R. A., Morell, C. M., Ridley, K., Zacharis, E. D., Petrus-Reurer, S., et al. (2022) · Nature Cell Biology

Single-cell and spatial transcriptomicsLiver physiology and pathology

Cited by 146

A human embryonic limb cell atlas resolved in space and time

Zhang, B., He, P., Lawrence, J. E. G., Wang, S., Tuck, E., Williams, B. A., Roberts, K., Kleshchevnikov, V., Mamanova, L., Bolt, L., et al. (2024) · Nature

Single-cell and spatial transcriptomicsDevelopmental Biology and Gene Regulation

Cited by 143

Multimodal decoding of human liver regeneration

Matchett, K. P., Wilson-Kanamori, J. R., Portman, J. R., Kapourani, C. A., Fercoq, F., May, S., Zajdel, E., Beltran, M., Sutherland, E. F., Mackey, J. B. G., et al. (2024) · Nature

Liver physiology and pathologyDrug-Induced Hepatotoxicity and Protection

Cited by 140

Single-cell transcriptomics for the assessment of cardiac disease

Miranda, A. M. A., Janbandhu, V., Maatz, H., Kanemaru, K., Cranley, J., Teichmann, S. A., Hübner, N., Schneider, M. D., Harvey, R. P., & Noseda, M. (2023) · Nature Reviews Cardiology

Single-cell and spatial transcriptomicsCongenital heart defects research

Cited by 117

From tissues to cell types and back: single-cell gene expression analysis of tissue architecture

Chen, X., Teichmann, S. A., & Meyer, K. B. (2018) · Annual Review of Biomedical Data Science

Single-cell and spatial transcriptomicsGene expression and cancer classification

Cited by 112

A prenatal skin atlas reveals immune regulation of human skin morphogenesis

Gopee, N. H., Winheim, E., Olabi, B., Admane, C., Foster, A. R., Huang, N., Botting, R. A., Torabi, F., Sumanaweera, D., Le, A. P., et al. (2024) · Nature

Hair Growth and DisordersSkin and Cellular Biology Research

Cited by 108

Computational approaches for interpreting sc RNA‐seq data

Rostom, R., Svensson, V., Teichmann, S. A., & Kar, G. (2017) · FEBS Letters

Single-cell and spatial transcriptomicsGene expression and cancer classification

Cited by 107

Structure and distribution of pentapeptide repeats in bacteria

Bateman, A., Murzin, A. G., & Teichmann, S. A. (1998) · Protein Science

Protein Structure and DynamicsBiochemical and Structural Characterization

Cited by 99

Systema: a framework for evaluating genetic perturbation response prediction beyond systematic variation

Viñas Torné, R., Wiatrak, M., Piran, Z., Fan, S., Jiang, L., Teichmann, S. A., Nitzan, M., & Brbić, M. (2026) · Nature Biotechnology

Gene Regulatory Network AnalysisBioinformatics and Genomic Networks

Cited by 58

Cotranslational protein assembly imposes evolutionary constraints on homomeric proteins

Natan, E., Endoh, T., Haim-Vilmovsky, L., Flock, T., Chalancon, G., Hopper, J. T. S., Kintses, B., Horvath, P., Daruka, L., Fekete, G., et al. (2018) · Nature Structural & Molecular Biology

RNA and protein synthesis mechanismsProtein Structure and Dynamics

Cited by 56

SOX9 maintains human foetal lung tip progenitor state by enhancing WNT and RTK signalling

Sun, D., Llora Batlle, O., van den Ameele, J., Thomas, J. C., He, P., Lim, K., Tang, W., Xu, C., Meyer, K. B., Teichmann, S. A., et al. (2022) · The EMBO Journal

Neonatal Respiratory Health ResearchDevelopmental Biology and Gene Regulation

Cited by 38

Duel of the fates: the role of transcriptional circuits and noise in CD4+ cells

Hebenstreit, D., Deonarine, A., Babu, M. M., & Teichmann, S. A. (2012) · Current Opinion in Cell Biology

Gene Regulatory Network AnalysisT-cell and B-cell Immunology

Cited by 20

CLICK-chemoproteomics and molecular dynamics simulation reveals pregnenolone targets and their binding conformations in Th2 cells

Roy, S., Roy, S., Mahata, B., Pramanik, J., Hennrich, M. L., Gavin, A.-C., & Teichmann, S. A. (2023) · Frontiers in Immunology

Click Chemistry and ApplicationsProtein Interaction Studies and Fluorescence Analysis

Cited by 5

CLICK- chemoproteomics and molecular dynamics simulation reveals pregnenolone targets and their binding conformations in Th2 cells

Roy, S., Roy, S., Mahata, B., Pramanik, J., Hennrich, M. L., Gavin, A.-C., & Teichmann, S. A. (2023) · Frontiers in Immunology

Click Chemistry and ApplicationsProtein Interaction Studies and Fluorescence Analysis

Cited by 5