Teichmann, Sarah A.

SpatialDE: identification of spatially variable genes

Svensson, V., Teichmann, S. A., & Stegle, O. (2018) · Nature Methods

Single-cell and spatial transcriptomicsGene expression and cancer classification

Cited by 695

Classification of low quality cells from single-cell RNA-seq data

Ilicic, T., Kim, J. K., Kolodziejczyk, A. A., Bagger, F. O., McCarthy, D. J., Marioni, J. C., & Teichmann, S. A. (2016) · Genome Biology

Single-cell and spatial transcriptomicsGene expression and cancer classification

Cited by 693

The Human Cell Atlas: from vision to reality

Rozenblatt-Rosen, O., Stubbington, M. J. T., Regev, A., & Teichmann, S. A. (2017) · Nature

Single-cell and spatial transcriptomicsGenomics and Chromatin Dynamics

Cited by 638

Decoding human fetal liver haematopoiesis

Popescu, D.-M., Botting, R. A., Stephenson, E., Green, K., Webb, S., Jardine, L., Calderbank, E. F., Polanski, K., Goh, I., Efremova, M., et al. (2019) · Nature

Hematopoietic Stem Cell TransplantationSingle-cell and spatial transcriptomics

Cited by 606

The human body at cellular resolution: the NIH Human Biomolecular Atlas Program

HuBMAP Consortium, Writing Group, Snyder, M. P., Lin, S., Posgai, A., Atkinson, M., Regev, A., Rood, J., Rozenblatt-Rosen, O., Gaffney, L., et al. (2019) · Nature

Single-cell and spatial transcriptomicsGenomics and Chromatin Dynamics

Cited by 595

Single Cell RNA-Sequencing of Pluripotent States Unlocks Modular Transcriptional Variation

Kolodziejczyk, A. A., Kim, J. K., Tsang, J. C. H., Ilicic, T., Henriksson, J., Natarajan, K. N., Tuck, A. C., Gao, X., Bühler, M., Liu, P., et al. (2015) · Cell Stem Cell

Pluripotent Stem Cells ResearchSingle-cell and spatial transcriptomics

Cited by 570

Power analysis of single-cell RNA-sequencing experiments

Svensson, V., Natarajan, K. N., Ly, L.-H., Miragaia, R. J., Labalette, C., Macaulay, I. C., Cvejic, A., & Teichmann, S. A. (2017) · Nature Methods

Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies

Cited by 568

Developmental cell programs are co-opted in inflammatory skin disease

Reynolds, G., Vegh, P., Fletcher, J., Poyner, E. F. M., Stephenson, E., Goh, I., Botting, R. A., Huang, N., Olabi, B., Dubois, A., et al. (2021) · Science

Dermatology and Skin DiseasesPsoriasis: Treatment and Pathogenesis

Cited by 529

A test metric for assessing single-cell RNA-seq batch correction

Büttner, M., Miao, Z., Wolf, F. A., Teichmann, S. A., & Theis, F. J. (2019) · Nature Methods

Single-cell and spatial transcriptomicsGene expression and cancer classification

Cited by 511

Single-Cell Transcriptomics of Regulatory T Cells Reveals Trajectories of Tissue Adaptation

Miragaia, R. J., Gomes, T., Chomka, A., Jardine, L., Riedel, A., Hegazy, A. N., Whibley, N., Tucci, A., Chen, X., Lindeman, I., et al. (2019) · Immunity

T-cell and B-cell ImmunologySingle-cell and spatial transcriptomics

Cited by 499

Tight Regulation of Unstructured Proteins: From Transcript Synthesis to Protein Degradation

Gsponer, J., Futschik, M. E., Teichmann, S. A., & Babu, M. M. (2008) · Science

Protein Structure and DynamicsRNA Research and Splicing

Cited by 466

Integrated Single-Cell Atlas of Endothelial Cells of the Human Lung

Schupp, J. C., Adams, T. S., Cosme, C., Raredon, M. S. B., Yuan, Y., Omote, N., Poli, S., Chioccioli, M., Rose, K.-A., Manning, E. P., et al. (2021) · Circulation

Single-cell and spatial transcriptomicsPulmonary Hypertension Research and Treatments

Cited by 453

Spatially resolved multiomics of human cardiac niches

Kanemaru, K., Cranley, J., Muraro, D., Miranda, A. M. A., Ho, S. Y., Wilbrey-Clark, A., Patrick Pett, J., Polanski, K., Richardson, L., Litvinukova, M., et al. (2023) · Nature

Single-cell and spatial transcriptomicsCardiac electrophysiology and arrhythmias

Cited by 425

Single-cell transcriptomics uncovers zonation of function in the mesenchyme during liver fibrosis

Dobie, R., Wilson-Kanamori, J. R., Henderson, B. E. P., Smith, J. R., Matchett, K. P., Portman, J. R., Wallenborg, K., Picelli, S., Zagorska, A., Pendem, S. V., et al. (2019) · Cell Reports

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 420

Cholangiocyte organoids can repair bile ducts after transplantation in the human liver

Sampaziotis, F., Muraro, D., Tysoe, O. C., Sawiak, S., Beach, T. E., Godfrey, E. M., Upponi, S. S., Brevini, T., Wesley, B. T., Garcia-Bernardo, J., et al. (2021) · Science

Liver physiology and pathologyOrgan Transplantation Techniques and Outcomes

Cited by 394

Local and systemic responses to SARS-CoV-2 infection in children and adults

Yoshida, M., Worlock, K. B., Huang, N., Lindeboom, R. G. H., Butler, C. R., Kumasaka, N., Dominguez Conde, C., Mamanova, L., Bolt, L., Richardson, L., et al. (2022) · Nature

SARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research Studies

Cited by 365

Single cell transcriptomics comes of age

Aldridge, S., & Teichmann, S. A. (2020) · Nature Communications

Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies

Cited by 360

Aging increases cell-to-cell transcriptional variability upon immune stimulation

Martinez-Jimenez, C. P., Eling, N., Chen, H.-C., Vallejos, C. A., Kolodziejczyk, A. A., Connor, F., Stojic, L., Rayner, T. F., Stubbington, M. J. T., Teichmann, S. A., et al. (2017) · Science

Single-cell and spatial transcriptomicsGenetics, Aging, and Longevity in Model Organisms

Cited by 339

Circulating and Tissue-Resident CD4+ T Cells With Reactivity to Intestinal Microbiota Are Abundant in Healthy Individuals and Function Is Altered During Inflammation

Hegazy, A. N., West, N. R., Stubbington, M. J. T., Wendt, E., Suijker, K. I. M., Datsi, A., This, S., Danne, C., Campion, S., Duncan, S. H., et al. (2017) · Gastroenterology

Gut microbiota and healthInflammatory Bowel Disease

Cited by 338

Single-cell RNA-seq identifies a PD-1hi ILC progenitor and defines its development pathway

Yu, Y., Tsang, J. C. H., Wang, C., Clare, S., Wang, J., Chen, X., Brandt, C., Kane, L., Campos, L. S., Lu, L., et al. (2016) · Nature

IL-33, ST2, and ILC PathwaysT-cell and B-cell Immunology

Cited by 306

RNA sequencing reveals two major classes of gene expression levels in metazoan cells

Hebenstreit, D., Fang, M., Gu, M., Charoensawan, V., van Oudenaarden, A., & Teichmann, S. A. (2011) · Molecular Systems Biology

Genomics and Chromatin DynamicsGenomics and Phylogenetic Studies

Cited by 289

Characterizing noise structure in single-cell RNA-seq distinguishes genuine from technical stochastic allelic expression

Kim, J. K., Kolodziejczyk, A. A., Ilicic, T., Teichmann, S. A., & Marioni, J. C. (2015) · Nature Communications

Single-cell and spatial transcriptomicsGene expression and cancer classification

Cited by 251

The Human Lung Cell Atlas: A High-Resolution Reference Map of the Human Lung in Health and Disease

Schiller, H. B., Montoro, D. T., Simon, L. M., Rawlins, E. L., Meyer, K. B., Strunz, M., Vieira Braga, F. A., Timens, W., Koppelman, G. H., Budinger, G. R. S., et al. (2019) · American Journal of Respiratory Cell and Molecular Biology

Single-cell and spatial transcriptomicsGenomics and Chromatin Dynamics

Cited by 245

Pathogenic variants damage cell composition and single cell transcription in cardiomyopathies

Reichart, D., Lindberg, E. L., Maatz, H., Miranda, A. M. A., Viveiros, A., Shvetsov, N., Gärtner, A., Nadelmann, E. R., Lee, M., Kanemaru, K., et al. (2022) · Science

Cardiomyopathy and Myosin StudiesCardiac electrophysiology and arrhythmias

Cited by 240