Hottenga, Jouke-Jan

Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors

Mullins, N., Kang, J., Campos, A. I., Coleman, J. R. I., Edwards, A. C., Galfalvy, H., Levey, D. F., Lori, A., Shabalin, A., Starnawska, A., et al. (2022) · Biological Psychiatry

Suicide and Self-Harm StudiesGenetic Associations and Epidemiology

Cited by 238

Gene expression in major depressive disorder

Jansen, R., Penninx, B. W. J. H., Madar, V, Xia, K., Milaneschi, Y., Hottenga, J. J., Hammerschlag, A. R., Beekman, A., van der Wee, N., Smit, J. H., et al. (2016) · Molecular Psychiatry

Tryptophan and brain disordersTreatment of Major Depression

Cited by 224

Effect of polygenic risk scores on depression in childhood trauma

Peyrot, W. J., Milaneschi, Y., Abdellaoui, A., Sullivan, P. F., Hottenga, J. J., Boomsma, D. I., & Penninx, B. W. J. H. (2014) · British Journal of Psychiatry

Genetic Associations and EpidemiologyChild Abuse and Trauma

Cited by 209

The Role of Adiposity in Cardiometabolic Traits: A Mendelian Randomization Analysis

Fall, T., Hägg, S., Mägi, R., Ploner, A., Fischer, K., Horikoshi, M., Sarin, A.-P., Thorleifsson, G., Ladenvall, C., Kals, M., et al. (2013) · PLoS Medicine

Genetic Associations and EpidemiologyAdipokines, Inflammation, and Metabolic Diseases

Cited by 203

Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity

Joshi, P. K., Pirastu, N., Kentistou, K. A., Fischer, K., Hofer, E., Schraut, K. E., Clark, D. W., Nutile, T., Barnes, C. L. K., Timmers, P. R. H. J., et al. (2017) · Nature Communications

Genetic Associations and EpidemiologyGenetics, Aging, and Longevity in Model Organisms

Cited by 161

Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns

Czamara, D., Eraslan, G., Page, C. M., Lahti, J., Lahti-Pulkkinen, M., Hämäläinen, E., Kajantie, E., Laivuori, H., Villa, P. M., Reynolds, R. M., et al. (2019) · Nature Communications

Epigenetics and DNA MethylationBirth, Development, and Health

Cited by 143

Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders

Arloth, J., Bogdan, R., Weber, P., Frishman, G., Menke, A., Wagner, K. V., Balsevich, G., Schmidt, M. V., Karbalai, N., Czamara, D., et al. (2015) · Neuron

Stress Responses and CortisolGenetic Associations and Epidemiology

Cited by 142

Conditional eQTL analysis reveals allelic heterogeneity of gene expression

Jansen, R., Hottenga, J.-J., Nivard, M. G., Abdellaoui, A., Laport, B., de Geus, E. J., Wright, F. A., Penninx, B. W. J. H., & Boomsma, D. I. (2017) · Human Molecular Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 141

Genetic Epidemiology of Attention Deficit Hyperactivity Disorder (ADHD Index) in Adults

Boomsma, D. I., Saviouk, V., Hottenga, J.-J., Distel, M. A., de Moor, M. H. M., Vink, J. M., Geels, L. M., van Beek, J. H. D. A., Bartels, M., de Geus, E. J. C., et al. (2010) · PLoS ONE

Attention Deficit Hyperactivity DisorderGenetic Associations and Epidemiology

Cited by 140

Association of Copy Number Variation of the 15q11.2 BP1-BP2 Region With Cortical and Subcortical Morphology and Cognition

Writing Committee for the ENIGMA-CNV Working Group, van der Meer, D., Sønderby, I. E., Kaufmann, T., Walters, G. B., Abdellaoui, A., Ames, D., Amunts, K., Andersson, M., Armstrong, N. J., et al. (2020) · JAMA Psychiatry

Genomic variations and chromosomal abnormalitiesGenetics and Neurodevelopmental Disorders

Cited by 87

The association between lower educational attainment and depression owing to shared genetic effects? Results in ~25 000 subjects

Peyrot, W. J., Lee, S. H., Milaneschi, Y., Abdellaoui, A., Byrne, E. M., Esko, T., de Geus, E. J. C., Hemani, G., Hottenga, J. J., Kloiber, S., et al. (2015) · Molecular Psychiatry

Genetic Associations and EpidemiologyNeurotransmitter Receptor Influence on Behavior

Cited by 84

The effect of FTO rs9939609 on major depression differs across MDD subtypes

Milaneschi, Y., Lamers, F., Mbarek, H., Hottenga, J.-J., Boomsma, D. I., & Penninx, B. W. J. H. (2014) · Molecular Psychiatry

Genetic Associations and EpidemiologyTreatment of Major Depression

Cited by 78

Increased Genetic Vulnerability to Smoking at CHRNA5 in Early-Onset Smokers

Hartz, S. M., Short, S. E., Saccone, N. L., Culverhouse, R., Chen, L., Schwantes-An, T.-H., Coon, H., Han, Y., Stephens, S. H., Sun, J., et al. (2012) · Archives of General Psychiatry

Smoking Behavior and CessationGenetic Associations and Epidemiology

Cited by 75

Genetic association study of childhood aggression across raters, instruments, and age

Ip, H. F., van der Laan, C. M., Krapohl, E. M. L., Brikell, I., Sánchez-Mora, C., Nolte, I. M., St Pourcain, B., Bolhuis, K., Palviainen, T., Zafarmand, H., et al. (2021) · Translational Psychiatry

Genetic Associations and EpidemiologyNeurotransmitter Receptor Influence on Behavior

Cited by 71

Effects of copy number variations on brain structure and risk for psychiatric illness: Large‐scale studies from the ENIGMA working groups on CNVs

Sønderby, I. E., Ching, C. R. K., Thomopoulos, S. I., van der Meer, D., Sun, D., Villalon‐Reina, J. E., Agartz, I., Amunts, K., Arango, C., Armstrong, N. J., et al. (2022) · Human Brain Mapping

Genomic variations and chromosomal abnormalitiesGenetic Associations and Epidemiology

Cited by 67

Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia

Sønderby, I. E., Gústafsson, Ó., Doan, N. T., Hibar, D. P., Martin-Brevet, S., Abdellaoui, A., Ames, D., Amunts, K., Andersson, M., Armstrong, N. J., et al. (2020) · Molecular Psychiatry

Genomic variations and chromosomal abnormalitiesGenetics and Neurodevelopmental Disorders

Cited by 66

The genetics of alcohol dependence: Twin and SNP‐based heritability, and genome‐wide association study based on AUDIT scores

Mbarek, H., Milaneschi, Y., Fedko, I. O., Hottenga, J., de Moor, M. H. M., Jansen, R., Gelernter, J., Sherva, R., Willemsen, G., Boomsma, D. I., et al. (2015) · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics

Genetic Associations and EpidemiologySubstance Abuse Treatment and Outcomes

Cited by 66

Genetic comorbidity between major depression and cardio‐metabolic traits, stratified by age at onset of major depression

Hagenaars, S. P., Coleman, J. R. I., Choi, S. W., Gaspar, H., Adams, M. J., Howard, D. M., Hodgson, K., Traylor, M., Air, T. M., Andlauer, T. F. M., et al. (2020) · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 61

Heritability and Genome-Wide Linkage Scan of Subjective Happiness

Bartels, M., Saviouk, V., de Moor, M. H. M., Willemsen, G., van Beijsterveldt, T. C. E. M., Hottenga, J.-J., de Geus, E. J. C., & Boomsma, D. I. (2010) · Twin Research and Human Genetics

Genetic Associations and EpidemiologyPsychological Well-being and Life Satisfaction

Cited by 56

Family-GWAS reveals effects of environment and mating on genetic associations

Tan, T., Jayashankar, H., Guan, J., Nehzati, S. M., Mir, M., Bennett, M., Agerbo, E., Ahlskog, R., de Andrade Anapaz, V. P., Benonisdottir, S., et al. (2024) · medRxiv

Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock

Cited by 47

Genetic Risk for Smoking: Disentangling Interplay Between Genes and Socioeconomic Status

Pasman, J. A., Demange, P. A., Guloksuz, S., Willemsen, A. H. M., Abdellaoui, A., ten Have, M., Hottenga, J.-J., Boomsma, D. I., de Geus, E., Bartels, M., et al. (2022) · Behavior Genetics

Genetic Associations and EpidemiologySmoking Behavior and Cessation

Cited by 41

Strong effects of environmental factors on prevalence and course of major depressive disorder are not moderated by 5-HTTLPR polymorphisms in a large Dutch sample

Peyrot, W. J., Middeldorp, C. M., Jansen, R., Smit, J. H., de Geus, E. J. C., Hottenga, J.-J., Willemsen, G., Vink, J. M., Virding, S., Barragan, I., et al. (2013) · Journal of Affective Disorders

Neurotransmitter Receptor Influence on BehaviorGenetic Associations and Epidemiology

Cited by 31