Klaver, Caroline C.W.

A common haplotype in the complement regulatory gene factor H ( HF1/CFH ) predisposes individuals to age-related macular degeneration

Hageman, G. S., Anderson, D. H., Johnson, L. V., Hancox, L. S., Taiber, A. J., Hardisty, L. I., Hageman, J. L., Stockman, H. A., Borchardt, J. D., Gehrs, K. M., et al. (2005) · Proceedings of the National Academy of Sciences

Retinal Diseases and TreatmentsComplement system in diseases

Cited by 1,961

An international classification and grading system for age-related maculopathy and age-related macular degeneration

Bird, A. C., Bressler, N. M., Bressler, S. B., Chisholm, I. H., Coscas, G., Davis, M. D., de Jong, P. T. V. M., Klaver, C. C. W., Klein, B. E. K., Klein, R., et al. (1995) · Survey of Ophthalmology

Retinal Diseases and TreatmentsRetinal Imaging and Analysis

Cited by 1,926

A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants

Fritsche, L. G., Igl, W., Bailey, J. N. C., Grassmann, F., Sengupta, S., Bragg-Gresham, J. L., Burdon, K. P., Hebbring, S. J., Wen, C., Gorski, M., et al. (2016) · Nature Genetics

Retinal Diseases and TreatmentsGenetic Associations and Epidemiology

Cited by 1,544

Risk factors for age-related macular degeneration

Smith, W., Assink, J., Klein, R., Mitchell, P., Klaver, C. C. W., Klein, B. E. K., Hofman, A., Jensen, S., Wang, J. J., & de Jong, P. T. V. M. (2001) · Ophthalmology

Retinal Diseases and TreatmentsRetinal Imaging and Analysis

Cited by 1,071

Non-syndromic retinitis pigmentosa

Verbakel, S. K., van Huet, R. A. C., Boon, C. J. F., den Hollander, A. I., Collin, R. W. J., Klaver, C. C. W., Hoyng, C. B., Roepman, R., & Klevering, B. J. (2018) · Progress in Retinal and Eye Research

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 973

Genetic Association of Apolipoprotein E with Age-Related Macular Degeneration

Klaver, C. C. W., Kliffen, M., van Duijn, C. M., Hofman, A., Cruts, M., Grobbee, D. E., van Broeckhoven, C., & de Jong, P. T. V. M. (1998) · The American Journal of Human Genetics

Retinal Diseases and TreatmentsRetinal Development and Disorders

Cited by 498

Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

Consortium for Refractive Error and Myopia (CREAM), Verhoeven, V. J. M., The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Research Group, Wellcome Trust Case Control Consortium 2 (WTCCC2), The Fuchs' Genetics Multi-Center Study Group, Hysi, P. G., Wojciechowski, R., Fan, Q., Guggenheim, J. A., Höhn, R., et al. (2013) · Nature Genetics

Ophthalmology and Visual Impairment StudiesGenetic Associations and Epidemiology

Cited by 487

Complement Factor H Polymorphism, Complement Activators, and Risk of Age-Related Macular Degeneration

Despriet, D. D. G., Klaver, C. C. W., Witteman, J. C. M., Bergen, A. A. B., Kardys, I., de Maat, M. P. M., Boekhoorn, S. S., Vingerling, J. R., Hofman, A., Oostra, B. A., et al. (2006) · JAMA

Retinal Diseases and TreatmentsComplement system in diseases

Cited by 348

Genetic Risk of Age-related Maculopathy: Population-Based Familial Aggregation Study

Klaver, C. C. W. (1998) · Archives of Ophthalmology

Retinal Diseases and TreatmentsRetinal Development and Disorders

Cited by 323

Three genome-wide association studies and a linkage analysis identify HERC2 as a human iris color gene

Kayser, M., Liu, F., Janssens, A. C. J. W., Rivadeneira, F., Lao, O., van Duijn, K., Vermeulen, M., Arp, P., Jhamai, M. M., van IJcken, W. F. J., et al. (2008) · The American Journal of Human Genetics

melanin and skin pigmentationGenetic Associations and Epidemiology

Cited by 260

Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration

Yu, Y., Bhangale, T. R., Fagerness, J., Ripke, S., Thorleifsson, G., Tan, P. L., Souied, E. H., Richardson, A. J., Merriam, J. E., Buitendijk, G. H. S., et al. (2011) · Human Molecular Genetics

Retinal Diseases and TreatmentsGenetic Associations and Epidemiology

Cited by 254

A new perspective on lipid research in age-related macular degeneration

van Leeuwen, E. M., Emri, E., Merle, B. M. J., Colijn, J. M., Kersten, E., Cougnard-Gregoire, A., Dammeier, S., Meester-Smoor, M., Pool, F. M., de Jong, E. K., et al. (2018) · Progress in Retinal and Eye Research

Retinal Diseases and TreatmentsRetinal Development and Disorders

Cited by 247

Is Age-related Maculopathy Associated with Alzheimer's Disease?: The Rotterdam Study

Klaver, C. C. W., Ott, A., Hofman, A., Assink, J. J. M., Breteler, M. M. B., & de Jong, P. T. V. M. (1999) · American Journal of Epidemiology

Dementia and Cognitive Impairment ResearchRetinal Diseases and Treatments

Cited by 162

Evidence of association of APOE with age-related macular degeneration - a pooled analysis of 15 studies

McKay, G. J., Patterson, C. C., Chakravarthy, U., Dasari, S., Klaver, C. C., Vingerling, J. R., Ho, L., de Jong, P. T. V. M., Fletcher, A. E., Young, I. S., et al. (2011) · Human Mutation

Retinal Diseases and TreatmentsRetinal Imaging and Analysis

Cited by 151

A pooled case-control study of the apolipoprotein E (APOE) gene in age-related maculopathy

Schmidt, S., Klaver, C. C. W., Saunders, A. M., Postel, E. A., De La Paz, M. A., Agarwal, A., Small, K. W., Udar, N., Ong, J. M., Chalukya, M. V., et al. (2002) · Ophthalmic Genetics

Retinal Diseases and TreatmentsRetinal Imaging and Analysis

Cited by 149

Diagnostic Accuracy of a Device for the Automated Detection of Diabetic Retinopathy in a Primary Care Setting

Verbraak, F. D., Abramoff, M. D., Bausch, G. C. F., Klaver, C., Nijpels, G., Schlingemann, R. O., & van der Heijden, A. A. (2019) · Diabetes Care

Retinal Imaging and AnalysisRetinal Diseases and Treatments

Cited by 115

Variations in Apolipoprotein E Frequency With Age in a Pooled Analysis of a Large Group of Older People

McKay, G. J., Silvestri, G., Chakravarthy, U., Dasari, S., Fritsche, L. G., Weber, B. H., Keilhauer, C. N., Klein, M. L., Francis, P. J., Klaver, C. C., et al. (2011) · American Journal of Epidemiology

Lipoproteins and Cardiovascular HealthRetinal Diseases and Treatments

Cited by 105

Trustworthy AI: Closing the gap between development and integration of AI systems in ophthalmic practice

González-Gonzalo, C., Thee, E. F., Klaver, C. C. W., Lee, A. Y., Schlingemann, R. O., Tufail, A., Verbraak, F., & Sánchez, C. I. (2022) · Progress in Retinal and Eye Research

Artificial Intelligence in Healthcare and EducationEthics and Social Impacts of AI

Cited by 103

Comprehensive candidate gene study highlights UGT1A and BNC2 as new genes determining continuous skin color variation in Europeans

Jacobs, L. C., Wollstein, A., Lao, O., Hofman, A., Klaver, C. C., Uitterlinden, A. G., Nijsten, T., Kayser, M., & Liu, F. (2013) · Human Genetics

melanin and skin pigmentationGenetic Associations and Epidemiology

Cited by 99

Complement Component C3 and Risk of Age-Related Macular Degeneration

Despriet, D. D. G., van Duijn, C. M., Oostra, B. A., Uitterlinden, A. G., Hofman, A., Wright, A. F., ten Brink, J. B., Bakker, A., de Jong, P. T. V. M., Vingerling, J. R., et al. (2009) · Ophthalmology

Retinal Diseases and TreatmentsComplement system in diseases

Cited by 94

Comprehensive Analysis of the Candidate Genes CCL2,CCR2, and TLR4 in Age-Related Macular Degeneration

Despriet, D. D. G., Bergen, A. A. B., Merriam, J. E., Zernant, J., Barile, G. R., Smith, R. T., Barbazetto, I. A., van Soest, S., Bakker, A., de Jong, P. T. V. M., et al. (2008) · Investigative Opthalmology & Visual Science

Retinal Diseases and TreatmentsRetinal Development and Disorders

Cited by 60

A transcriptome-wide association study based on 27 tissues identifies 106 genes potentially relevant for disease pathology in age-related macular degeneration

Strunz, T., Lauwen, S., Kiel, C., International AMD Genomics Consortium (IAMDGC), Fritsche, L. G., Igl, W., Bailey, J. N. C., Grassmann, F., Sengupta, S., Bragg-Gresham, J. L., et al. (2020) · Scientific Reports

Genetic Associations and EpidemiologyRetinal Diseases and Treatments

Cited by 60

Genotype- and Phenotype-Based Subgroups in Geographic Atrophy Secondary to Age-Related Macular Degeneration

Biarnés, M., Colijn, J. M., Sousa, J., Ferraro, L. L., Garcia, M., Verzijden, T., Meester-Smoor, M. A., Delcourt, C., Klaver, C. C. W., den Hollander, A. I., et al. (2020) · Ophthalmology Retina

Retinal Diseases and TreatmentsRetinal Imaging and Analysis

Cited by 40

Cone-rod dystrophy can be a manifestation of Danon disease

Thiadens, A. A. H. J., Slingerland, N. W. R., Florijn, R. J., Visser, G. H., Riemslag, F. C., & Klaver, C. C. W. (2012) · Graefe s Archive for Clinical and Experimental Ophthalmology

Retinal Development and DisordersLysosomal Storage Disorders Research

Cited by 36