Treebak, Jonas T.

Acute Exercise Remodels Promoter Methylation in Human Skeletal Muscle

Barrès, R., Yan, J., Egan, B., Treebak, J. T., Rasmussen, M., Fritz, T., Caidahl, K., Krook, A., O'Gorman, D. J., & Zierath, J. R. (2012) · Cell Metabolism

Epigenetics and DNA MethylationMuscle Physiology and Disorders

Cited by 965

A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes

Moltke, I., Grarup, N., Jørgensen, M. E., Bjerregaard, P., Treebak, J. T., Fumagalli, M., Korneliussen, T. S., Andersen, M. A., Nielsen, T. S., Krarup, N. T., et al. (2014) · Nature

Genetic Associations and EpidemiologyDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 418

Time of exercise specifies the impact on muscle metabolic pathways and systemic energy homeostasis

Sato, S., Basse, A. L., Schönke, M., Chen, S., Samad, M., Altıntaş, A., Laker, R. C., Dalbram, E., Barrès, R., Baldi, P., et al. (2019) · Cell Metabolism

Circadian rhythm and melatoninMetabolism, Diabetes, and Cancer

Cited by 298

A randomized placebo-controlled clinical trial of nicotinamide riboside in obese men: safety, insulin-sensitivity, and lipid-mobilizing effects

Dollerup, O. L., Christensen, B., Svart, M., Schmidt, M. S., Sulek, K., Ringgaard, S., Stødkilde-Jørgensen, H., Møller, N., Brenner, C., Treebak, J. T., et al. (2018) · The American Journal of Clinical Nutrition

Sirtuins and Resveratrol in MedicineFolate and B Vitamins Research

Cited by 282

AMPK controls exercise endurance, mitochondrial oxidative capacity, and skeletal muscle integrity.

Lantier, L., Fentz, J., Mounier, R., Leclerc, J., Treebak, J. T., Pehmøller, C., Sanz, N., Sakakibara, I., Saint‐Amand, E., Rimbaud, S., et al. (2014) · The FASEB Journal

Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism

Cited by 228

Cytosolic ROS production by NADPH oxidase 2 regulates muscle glucose uptake during exercise

Henríquez-Olguin, C., Knudsen, J. R., Raun, S. H., Li, Z., Dalbram, E., Treebak, J. T., Sylow, L., Holmdahl, R., Richter, E. A., Jaimovich, E., et al. (2019) · Nature Communications

Exercise and Physiological ResponsesRedox biology and oxidative stress

Cited by 228

Atlas of exercise metabolism reveals time-dependent signatures of metabolic homeostasis

Sato, S., Dyar, K. A., Treebak, J. T., Jepsen, S. L., Ehrlich, A. M., Ashcroft, S. P., Trost, K., Kunzke, T., Prade, V. M., Small, L., et al. (2022) · Cell Metabolism

Circadian rhythm and melatoninExercise and Physiological Responses

Cited by 203

Enhanced muscle insulin sensitivity after contraction/exercise is mediated by AMPK

Kjøbsted, R., Munk-Hansen, N., Birk, J. B., Foretz, M., Viollet, B., Björnholm, M., Zierath, J. R., Treebak, J. T., & Wojtaszewski, J. F. P. (2017) · Diabetes

Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism

Cited by 178

Genetic disruption of AMPK signaling abolishes both contraction- and insulin-stimulated TBC1D1 phosphorylation and 14-3-3 binding in mouse skeletal muscle

Pehmøller, C., Treebak, J. T., Birk, J. B., Chen, S., MacKintosh, C., Hardie, D. G., Richter, E. A., & Wojtaszewski, J. F. P. (2009) · American Journal of Physiology-Endocrinology and Metabolism

Metabolism, Diabetes, and CancerCellular transport and secretion

Cited by 171

Molecular Mechanism by Which AMP-Activated Protein Kinase Activation Promotes Glycogen Accumulation in Muscle

Hunter, R. W., Treebak, J. T., Wojtaszewski, J. F. P., & Sakamoto, K. (2011) · Diabetes

Metabolism, Diabetes, and CancerGlycogen Storage Diseases and Myoclonus

Cited by 151

Trigonelline Is an NAD+ Precursor That Improves Muscle Function during Ageing and Is Reduced in Human Sarcopenia

Membrez, M., Migliavacca, E., Christen, S., Yaku, K., Trieu, J., Lee, A. K., Morandini, F., Giner, M. P., Stiner, J., Makarov, M. V., et al. (2024) · Nature Metabolism

Sirtuins and Resveratrol in MedicineNutrition and Health in Aging

Cited by 148

Nicotinamide riboside does not alter mitochondrial respiration, content or morphology in skeletal muscle from obese and insulin‐resistant men

Dollerup, O. L., Chubanava, S., Agerholm, M., Søndergård, S. D., Altıntaş, A., Møller, A. B., Høyer, K. F., Ringgaard, S., Stødkilde‐Jørgensen, H., Lavery, G. G., et al. (2020) · The Journal of Physiology

Sirtuins and Resveratrol in MedicineAdipose Tissue and Metabolism

Cited by 145

Glucagon acutely regulates hepatic amino acid catabolism and the effect may be disturbed by steatosis

Winther-Sørensen, M., Galsgaard, K. D., Santos, A., Trammell, S. A. J., Sulek, K., Kuhre, R. E., Pedersen, J., Andersen, D. B., Hassing, A. S., Dall, M., et al. (2020) · Molecular Metabolism

Liver Disease Diagnosis and TreatmentPancreatic function and diabetes

Cited by 135

Impaired insulin-induced site-specific phosphorylation of TBC1 domain family, member 4 (TBC1D4) in skeletal muscle of type 2 diabetes patients is restored by endurance exercise-training.

Vind, B. F., Pehmøller, C., Treebak, J. T., Birk, J. B., Hey-Mogensen, M., Beck-Nielsen, H., Zierath, J. R., Wojtaszewski, J. F. P., & Højlund, K. (2011) · Diabetologia

Metabolism, Diabetes, and CancerDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 129

Potential role of TBC1D4 in enhanced post-exercise insulin action in human skeletal muscle

Treebak, J. T., Frøsig, C., Pehmøller, C., Chen, S., Maarbjerg, S. J., Brandt, N., MacKintosh, C., Zierath, J. R., Hardie, D. G., Kiens, B., et al. (2009) · Diabetologia

Metabolism, Diabetes, and CancerMuscle metabolism and nutrition

Cited by 119

Acute exercise and physiological insulin induce distinct phosphorylation signatures on TBC1D1 and TBC1D4 proteins in human skeletal muscle

Treebak, J. T., Pehmøller, C., Kristensen, J. M., Kjøbsted, R., Birk, J. B., Schjerling, P., Richter, E. A., Goodyear, L. J., & Wojtaszewski, J. F. P. (2014) · The Journal of Physiology

Metabolism, Diabetes, and CancerMuscle metabolism and nutrition

Cited by 113

Aerobic and resistance exercise training reverses age‐dependent decline in NAD+salvage capacity in human skeletal muscle

de Guia, R. M., Agerholm, M., Nielsen, T. S., Consitt, L. A., Søgaard, D., Helge, J. W., Larsen, S., Brandauer, J., Houmard, J. A., & Treebak, J. T. (2019) · Physiological Reports

Sirtuins and Resveratrol in MedicineExercise and Physiological Responses

Cited by 99

Sucrose nonfermenting AMPK-related kinase (SNARK) mediates contraction-stimulated glucose transport in mouse skeletal muscle

Koh, H.-J., Toyoda, T., Fujii, N., Jung, M. M., Rathod, A., Middelbeek, R. J.-W., Lessard, S. J., Treebak, J. T., Tsuchihara, K., Esumi, H., et al. (2010) · Proceedings of the National Academy of Sciences

Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism

Cited by 94

Effects of Nicotinamide Riboside on Endocrine Pancreatic Function and Incretin Hormones in Nondiabetic Men With Obesity

Dollerup, O. L., Trammell, S. A. J., Hartmann, B., Holst, J. J., Christensen, B., Møller, N., Gillum, M. P., Treebak, J. T., & Jessen, N. (2019) · The Journal of Clinical Endocrinology & Metabolism

Sirtuins and Resveratrol in MedicinePancreatic function and diabetes

Cited by 77

Skeletal muscle insulin sensitivity show circadian rhythmicity which is independent of exercise training status

Basse, A. L., Dalbram, E., Larsson, L., Gerhart-Hines, Z., Zierath, J. R., & Treebak, J. T. (2018) · Frontiers in Physiology

Circadian rhythm and melatoninMetabolism, Diabetes, and Cancer

Cited by 52

Role of Adenosine 5′-Monophosphate-Activated Protein Kinase Subunits in Skeletal Muscle Mammalian Target of Rapamycin Signaling

Deshmukh, A. S., Treebak, J. T., Long, Y. C., Viollet, B., Wojtaszewski, J. F. P., & Zierath, J. R. (2008) · Molecular Endocrinology

Metabolism, Diabetes, and CancerPI3K/AKT/mTOR signaling in cancer

Cited by 44

A randomized placebo-controlled trial of nicotinamide riboside and pterostilbene supplementation in experimental muscle injury in elderly individuals

Jensen, J. B., Dollerup, O. L., Møller, A. B., Billeskov, T. B., Dalbram, E., Chubanava, S., Damgaard, M. V., Dellinger, R. W., Trošt, K., Moritz, T., et al. (2022) · JCI Insight

Muscle Physiology and DisordersExercise and Physiological Responses

Cited by 39

Sustained AS160 and TBC1D1 phosphorylations in human skeletal muscle 30 min after a single bout of exercise

Vendelbo, M. H., Møller, A. B., Treebak, J. T., Gormsen, L. C., Goodyear, L. J., Wojtaszewski, J. F. P., Jørgensen, J. O. L., Møller, N., & Jessen, N. (2014) · Journal of Applied Physiology

Metabolism, Diabetes, and CancerCardiovascular and exercise physiology

Cited by 34

Insulin- and exercise-induced phosphoproteomics of human skeletal muscle identify REPS1 as a regulator of muscle glucose uptake

Kjærgaard, J., Lindqvist, C. B., Quesada, J. P., Jessen, S., Schlabs, F., Ehrlich, A. M., Yonamine, C. Y., García-Ureña, M., Schmalbruch, J. H., Small, L., et al. (2025) · Cell Reports Medicine

Metabolism, Diabetes, and CancerMuscle metabolism and nutrition

Cited by 11