A randomized placebo-controlled trial of nicotinamide riboside and pterostilbene supplementation in experimental muscle injury in elderly individuals

Sarcopenia: revised European consensus on definition and diagnosis

Cruz-Jentoft, A. J., Bahat, G., Bauer, J., Boirie, Y., Bruyère, O., Cederholm, T., Cooper, C., Landi, F., Rolland, Y., Sayer, A. A., et al. (2019) · Age and Ageing · doi:10.1093/ageing/afy169 · Cited by 13,818 · see citing works

MZmine 2: Modular framework for processing, visualizing, and analyzing mass spectrometry-based molecular profile data

Pluskal, T., Castillo, S., Villar‐Briones, A., & Orešič, M. (2010) · BMC Bioinformatics · doi:10.1186/1471-2105-11-395 · Cited by 3,852 · see citing works

Sarcopenia: revised European consensus on definition and diagnosis

Cruz-Jentoft, A. J., Bahat, G., Bauer, J., Boirie, Y., Bruyère, O., Cederholm, T., Cooper, C., Landi, F., Rolland, Y., Sayer, A. A., et al. (2019) · Age and Ageing · doi:10.1093/ageing/afz046 · Cited by 3,803 · see citing works

Rejuvenation of aged progenitor cells by exposure to a young systemic environment

Conboy, I. M., Conboy, M. J., Wagers, A. J., Girma, E. R., Weissman, I. L., & Rando, T. A. (2005) · Nature · doi:10.1038/nature03260 · Cited by 2,287 · see citing works

Nicotinamide Mononucleotide, a Key NAD+ Intermediate, Treats the Pathophysiology of Diet- and Age-Induced Diabetes in Mice

Yoshino, J., Mills, K. F., Yoon, M. J., & Imai, S.-I. (2011) · Cell Metabolism · doi:10.1016/j.cmet.2011.08.014 · Cited by 1,340 · see citing works

NAD ⁺ in aging, metabolism, and neurodegeneration

Verdin, E. (2015) · Science · doi:10.1126/science.aac4854 · Cited by 1,319 · see citing works

NAD ⁺ repletion improves mitochondrial and stem cell function and enhances life span in mice

Zhang, H., Ryu, D., Wu, Y., Gariani, K., Wang, X., Luan, P., D’Amico, D., Ropelle, E. R., Lutolf, M. P., Aebersold, R., et al. (2016) · Science · doi:10.1126/science.aaf2693 · Cited by 1,255 · cited 4× · see citing works

mTORC1 controls the adaptive transition of quiescent stem cells from G0 to GAlert

Rodgers, J. T., King, K. Y., Brett, J. O., Cromie, M. J., Charville, G. W., Maguire, K. K., Brunson, C., Mastey, N., Liu, L., Tsai, C.-R., et al. (2014) · Nature · doi:10.1038/nature13255 · Cited by 776 · see citing works

Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults

Martens, C. R., Denman, B. A., Mazzo, M. R., Armstrong, M. L., Reisdorph, N., McQueen, M. B., Chonchol, M., & Seals, D. R. (2018) · Nature Communications · doi:10.1038/s41467-018-03421-7 · Cited by 588 · see citing works

The NAD+-Dependent SIRT1 Deacetylase Translates a Metabolic Switch into Regulatory Epigenetics in Skeletal Muscle Stem Cells

Ryall, J. G., Dell’Orso, S., Derfoul, A., Juan, A., Zare, H., Feng, X., Clermont, D., Koulnis, M., Gutierrez-Cruz, G., Fulco, M., et al. (2015) · Cell Stem Cell · doi:10.1016/j.stem.2014.12.004 · Cited by 575 · see citing works

Age-Associated Changes In Oxidative Stress and NAD+ Metabolism In Human Tissue

Massudi, H., Grant, R., Braidy, N., Guest, J., Farnsworth, B., & Guillemin, G. J. (2012) · PLoS ONE · doi:10.1371/journal.pone.0042357 · Cited by 545 · cited 1× · see citing works

Comparative Study of Injury Models for Studying Muscle Regeneration in Mice

Hardy, D., Besnard, A., Latil, M., Jouvion, G., Briand, D., Thépenier, C., Pascal, Q., Guguin, A., Gayraud-Morel, B., Cavaillon, J., et al. (2016) · PLoS ONE · doi:10.1371/journal.pone.0147198 · Cited by 512 · see citing works

In vivo NAD assay reveals the intracellular NAD contents and redox state in healthy human brain and their age dependences

Zhu, X.-H., Lu, M., Lee, B.-Y., Ugurbil, K., & Chen, W. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1417921112 · Cited by 468 · see citing works

Nicotinamide Riboside Augments the Aged Human Skeletal Muscle NAD+ Metabolome and Induces Transcriptomic and Anti-inflammatory Signatures

Elhassan, Y. S., Kluckova, K., Fletcher, R. S., Schmidt, M. S., Garten, A., Doig, C. L., Cartwright, D. M., Oakey, L., Burley, C. V., Jenkinson, N., et al. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.07.043 · Cited by 448 · see citing works

Short-Term Calorie Restriction Enhances Skeletal Muscle Stem Cell Function

Cerletti, M., Jang, Y. C., Finley, L. W. S., Haigis, M. C., & Wagers, A. J. (2012) · Cell stem cell · doi:10.1016/j.stem.2012.04.002 · Cited by 397 · see citing works

Muscle Mass Index As a Predictor of Longevity in Older Adults

Srikanthan, P., & Karlamangla, A. S. (2014) · The American Journal of Medicine · doi:10.1016/j.amjmed.2014.02.007 · Cited by 382 · see citing works

Loss of NAD Homeostasis Leads to Progressive and Reversible Degeneration of Skeletal Muscle

Frederick, D. W., Loro, E., Liu, L., Davila, A., Chellappa, K., Silverman, I. M., Quinn, W. J., Gosai, S. J., Tichy, E. D., Davis, J. G., et al. (2016) · Cell Metabolism · doi:10.1016/j.cmet.2016.07.005 · Cited by 367 · cited 1× · see citing works

A Review of Pterostilbene Antioxidant Activity and Disease Modification

McCormack, D., & McFadden, D. W. (2013) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2013/575482 · Cited by 340 · see citing works

Myofibre damage in human skeletal muscle: effects of electrical stimulation <i>versus</i> voluntary contraction

Crameri, R. M., Aagaard, P., Qvortrup, K., Langberg, H., Olesen, J., & Kjær, M. (2007) · The Journal of Physiology · doi:10.1113/jphysiol.2007.128827 · Cited by 319 · see citing works

The regulation of nicotinamide adenine dinucleotide biosynthesis by Nampt/PBEF/visfatin in mammals

Revollo, J. R., Grimm, A. A., & Imai, S. (2007) · Current Opinion in Gastroenterology · doi:10.1097/mog.0b013e32801b3c8f · Cited by 311 · see citing works

Satellite cells and myonuclei in young and elderly women and men

Kadi, F., Charifi, N., Denis, C., & Lexell, J. E. (2003) · Muscle & Nerve · doi:10.1002/mus.10510 · Cited by 283 · see citing works

Niacin Cures Systemic NAD+ Deficiency and Improves Muscle Performance in Adult-Onset Mitochondrial Myopathy

Pirinen, E., Auranen, M., Khan, N. A., Brilhante, V., Urho, N., Pessia, A., Hakkarainen, A., Kuula, J., Heinonen, U., Schmidt, M. S., et al. (2020) · Cell Metabolism · doi:10.1016/j.cmet.2020.04.008 · Cited by 279 · see citing works

An open-label, non-randomized study of the pharmacokinetics of the nutritional supplement nicotinamide riboside (NR) and its effects on blood NAD+ levels in healthy volunteers

Airhart, S. E., Shireman, L. M., Risler, L. J., Anderson, G. D., Gowda, G. A. N., Raftery, D., Tian, R., Shen, D. D., & O’Brien, K. D. (2017) · PLoS ONE · doi:10.1371/journal.pone.0186459 · Cited by 260 · see citing works

SMASH – semi-automatic muscle analysis using segmentation of histology: a MATLAB application

Smith, L., & Barton, E. R. (2014) · Skeletal Muscle · doi:10.1186/2044-5040-4-21 · Cited by 223 · see citing works

Hepatic NAD+ deficiency as a therapeutic target for non‐alcoholic fatty liver disease in ageing

Zhou, C., Yang, X., Hua, X., Liu, J., Fan, M.-B., Li, G., Song, J., Xu, T., Li, Z., Guan, Y., et al. (2016) · British Journal of Pharmacology · doi:10.1111/bph.13513 · Cited by 198 · see citing works

Ex Vivo Expansion and In Vivo Self-Renewal of Human Muscle Stem Cells

Charville, G. W., Cheung, T. H., Yoo, B., Santos, P. J. F., Lee, G., Shrager, J. B., & Rando, T. A. (2015) · Stem Cell Reports · doi:10.1016/j.stemcr.2015.08.004 · Cited by 196 · see citing works

Extraction and Quantitation of Nicotinamide Adenine Dinucleotide Redox Cofactors

Lu, W., Wang, L., Chen, L., Hui, S. T., & Rabinowitz, J. D. (2017) · Antioxidants and Redox Signaling · doi:10.1089/ars.2017.7014 · Cited by 190 · see citing works

Repeat dose NRPT (nicotinamide riboside and pterostilbene) increases NAD(+) levels in humans safely and sustainably: a randomized, double-blind, placebo-controlled study

Dellinger, R. W., Santos, S. R., Morris, M., Evans, M., Alminana, D., Guarente, L., & Marcotulli, E. (2017) · npj Aging and Mechanisms of Disease · doi:10.1038/s41514-017-0016-9 · Cited by 181 · see citing works

Muscle stem cell aging: regulation and rejuvenation

Sousa-Victor, P., García-Prat, L., Serrano, A. L., Perdiguero, E., & Muñoz-Cánoves, P. (2015) · Trends in Endocrinology &amp; Metabolism · doi:10.1016/j.tem.2015.03.006 · Cited by 163 · see citing works

Exercise rejuvenates quiescent skeletal muscle stem cells in old mice through restoration of Cyclin D1

Brett, J. O., Arjona, M., Ikeda, M., Quarta, M., de Morrée, A., Egner, I. M., Perandini, L. A., Ishak, H. D., Goshayeshi, A., Benjamin, D. I., et al. (2020) · Nature Metabolism · doi:10.1038/s42255-020-0190-0 · Cited by 162 · see citing works

Nicotinamide riboside supplementation alters body composition and skeletal muscle acetylcarnitine concentrations in healthy obese humans

Remie, C. M., Roumans, K. H., Moonen, M. P., Connell, N. J., Havekes, B., Mevenkamp, J., Lindeboom, L., de Wit, V. H., van de Weijer, T., Aarts, S. A., et al. (2020) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqaa072 · Cited by 160 · see citing works

Human skeletal muscle CD90+ fibro-adipogenic progenitors are associated with muscle degeneration in type 2 diabetic patients

Farup, J., Just, J., de Paoli, F. V., Lin, L., Jensen, J., Billeskov, T. B., Sánchez-Román, I., Cömert, C., Møller, A. B., Madaro, L., et al. (2021) · Cell Metabolism · doi:10.1016/j.cmet.2021.10.001 · Cited by 154 · see citing works

Nicotinamide riboside does not alter mitochondrial respiration, content or morphology in skeletal muscle from obese and insulin‐resistant men

Dollerup, O. L., Chubanava, S., Agerholm, M., Søndergård, S. D., Altıntaş, A., Møller, A. B., Høyer, K. F., Ringgaard, S., Stødkilde‐Jørgensen, H., Lavery, G. G., et al. (2020) · The Journal of Physiology · doi:10.1113/jp278752 · Cited by 145 · see citing works

Rejuvenation of three germ layers tissues by exchanging old blood plasma with saline-albumin

Mehdipour, M., Skinner, C. M., Wong, N., Lieb, M., Liu, C., Etienne, J., Kato, C., KIPROV, D. D., Conboy, M. J., & Conboy, I. M. (2020) · Aging · doi:10.18632/aging.103418 · Cited by 114 · see citing works

Reduced Satellite Cell Numbers with Spinal Cord Injury and Aging in Humans

Verdijk, L. B., Dirks, M. L., Snijders, T., Prompers, J. J., Beelen, M., Jonkers, R. A. M., Thijssen, D. H. J., Hopman, M. T. E., & van Loon, L. J. C. (2012) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e3182667c2e · Cited by 107 · see citing works

Activation of satellite cells and the regeneration of human skeletal muscle are expedited by ingestion of nonsteroidal anti-inflammatory medication

Mackey, A. L., Rasmussen, L. K., Kadi, F., Schjerling, P., Helmark, I. C., Ponsot, E., Aagaard, P., Durigan, J. L. Q., & Kjaer, M. (2016) · The FASEB Journal · doi:10.1096/fj.201500198r · Cited by 99 · see citing works

Aerobic and resistance exercise training reverses age‐dependent decline in NAD⁺salvage capacity in human skeletal muscle

de Guia, R. M., Agerholm, M., Nielsen, T. S., Consitt, L. A., Søgaard, D., Helge, J. W., Larsen, S., Brandauer, J., Houmard, J. A., & Treebak, J. T. (2019) · Physiological Reports · doi:10.14814/phy2.14139 · Cited by 99 · see citing works

Efficacy and tolerability of EH301 for amyotrophic lateral sclerosis: a randomized, double-blind, placebo-controlled human pilot study

de la Rubia, J. E., Drehmer, E., Platero, J. L., Benlloch, M., Caplliure-Llopis, J., Villaron-Casales, C., de Bernardo, N., AlarcÓn, J., Fuente, C., Carrera, S., et al. (2019) · Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration · doi:10.1080/21678421.2018.1536152 · Cited by 92 · see citing works

SIRT1 activation by pterostilbene attenuates the skeletal muscle oxidative stress injury and mitochondrial dysfunction induced by ischemia reperfusion injury

Cheng, Y., Di, S., Fan, C., Cai, L., Gao, C., Jiang, P., Hu, W., Ma, Z., Jiang, S., Dong, Y., et al. (2016) · APOPTOSIS · doi:10.1007/s10495-016-1258-x · Cited by 91 · see citing works

Preserved capacity for satellite cell proliferation, regeneration, and hypertrophy in the skeletal muscle of healthy elderly men

Karlsen, A., Soendenbroe, C., Malmgaard‐Clausen, N. M., Wagener, F., Moeller, C. E., Senhaji, Z., Damberg, K., Andersen, J. L., Schjerling, P., Kjær, M., et al. (2020) · The FASEB Journal · doi:10.1096/fj.202000196r · Cited by 71 · see citing works

Loss of NAMPT in aging retinal pigment epithelium reduces NAD+ availability and promotes cellular senescence

Jadeja, R. N., Powell, F. L., Jones, M. A., Fuller, J., Joseph, E., Thounaojam, M. C., Bartoli, M., & Martin, P. M. (2018) · Aging · doi:10.18632/aging.101469 · Cited by 69 · see citing works

Nampt controls skeletal muscle development by maintaining Ca2+ homeostasis and mitochondrial integrity

Basse, A. L., Agerholm, M., Farup, J., Dalbram, E., Nielsen, J., Ørtenblad, N., Altıntaş, A., Ehrlich, A. M., Krag, T. O. B., Bruzzone, S., et al. (2021) · Molecular Metabolism · doi:10.1016/j.molmet.2021.101271 · Cited by 62 · see citing works

Niacin Cures Systemic NAD+ Deficiency and Improves Muscle Performance in Adult-Onset Mitochondrial Myopathy

Pirinen, E., Auranen, M., Khan, N. A., Brilhante, V., Urho, N., Pessia, A., Hakkarainen, A., Kuula, J., Schmidt, M. S., Haimilahti, K., et al. (2020) · Cell Metabolism · doi:10.1016/j.cmet.2020.05.020 · Cited by 47 · see citing works

Nicotinamide riboside supplementation does not alter whole‐body or skeletal muscle metabolic responses to a single bout of endurance exercise

Stocks, B., Ashcroft, S. P., Joanisse, S., Dansereau, L. C., Koay, Y. C., Elhassan, Y., Lavery, G. G., Quek, L., O’Sullivan, J., Philp, A. M., et al. (2021) · The Journal of Physiology · doi:10.1113/jp280825 · Cited by 44 · see citing works

Perturbations of NAD+salvage systems impact mitochondrial function and energy homeostasis in mouse myoblasts and intact skeletal muscle

Agerholm, M., Dall, M., Jensen, B. A. H., Prats, C., Madsen, S., Basse, A. L., Graae, A.-S., Risis, S., Goldenbaum, J., Quistorff, B., et al. (2017) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00213.2017 · Cited by 43 · see citing works

Nicotinamide riboside with pterostilbene (NRPT) increases NAD+ in patients with acute kidney injury (AKI): a randomized, double-blind, placebo-controlled, stepwise safety study of escalating doses of NRPT in patients with AKI

Šimić, P., Parada, X. F. V., Parikh, S. M., Dellinger, R. W., Guarente, L., & Rhee, E. P. (2020) · BMC Nephrology · doi:10.1186/s12882-020-02006-1 · Cited by 42 · see citing works

Intravenous nicotinamide riboside elevates mouse skeletal muscle NAD+ without impacting respiratory capacity or insulin sensitivity

Damgaard, M. V., Nielsen, T. S., Basse, A. L., Chubanava, S., Trôst, K., Möritz, T., Dellinger, R. W., Larsen, S., & Treebak, J. T. (2022) · iScience · doi:10.1016/j.isci.2022.103863 · Cited by 25 · see citing works

Isolation and characterization of muscle stem cells, fibro-adipogenic progenitors, and macrophages from human skeletal muscle biopsies

Jensen, J., Møller, A. B., Just, J., Mose, M., de Paoli, F. V., Billeskov, T. B., Fred, R. G., Pers, T. H., Pedersen, S. B., Petersen, K. K., et al. (2021) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00127.2021 · Cited by 21 · see citing works

NAD metabolism: Role in senescence regulation and aging

Chini, C. C. S., Cordeiro, H. S., Tran, N. L. K., & Chini, E. N. (2023) · Aging Cell · doi:10.1111/acel.13920 · Cited by 138 · see citing works

Regulation of and challenges in targeting NAD+ metabolism

Migaud, M. E., Ziegler, M., & Baur, J. A. (2024) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-024-00752-w · Cited by 134 · see citing works

Impaired skeletal muscle regeneration in diabetes: From cellular and molecular mechanisms to novel treatments

Espino-González, E., Dalbram, E., Mounier, R., Gondin, J., Farup, J., Jessen, N., & Treebak, J. T. (2024) · Cell Metabolism · doi:10.1016/j.cmet.2024.02.014 · Cited by 132 · see citing works

Therapeutic application of natural products: NAD+ metabolism as potential target

Guo, C., Huang, Q., Wang, Y., Yao, Y., Li, J., Chen, J., Wu, M., Zhang, Z., Mingyao, E., Qi, H., et al. (2023) · Phytomedicine · doi:10.1016/j.phymed.2023.154768 · Cited by 113 · see citing works

What is really known about the effects of nicotinamide riboside supplementation in humans

Damgaard, M. V., & Treebak, J. T. (2023) · Science Advances · doi:10.1126/sciadv.adi4862 · Cited by 102 · see citing works

Dietary Supplementation With NAD+-Boosting Compounds in Humans: Current Knowledge and Future Directions

Freeberg, K. A., Udovich, C. C., Martens, C. R., Seals, D. R., & Craighead, D. H. (2023) · The Journals of Gerontology Series A · doi:10.1093/gerona/glad106 · Cited by 67 · see citing works

Complementing muscle regeneration—fibro-adipogenic progenitor and macrophage-mediated repair of elderly human skeletal muscle

Brorson, J., Lin, L., Wang, J., Bæk, A., Billeskov, T. B., Thybo, F. F., Just, J., Haskó, J., Ravn, C., Hansen, R. L., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-60627-2 · Cited by 59 · see citing works

Clinical Trials Targeting Aging

Nielsen, J. L., Bakula, D., & Scheibye‐Knudsen, M. (2022) · Frontiers in Aging · doi:10.3389/fragi.2022.820215 · Cited by 51 · see citing works

Nicotinamide Adenine Dinucleotide in Aging Biology: Potential Applications and Many Unknowns

Bhasin, S., Seals, D. R., Migaud, M. E., Musi, N., & Baur, J. A. (2023) · Endocrine Reviews · doi:10.1210/endrev/bnad019 · Cited by 47 · see citing works

ATP and NAD+ Deficiency in Parkinson’s Disease

Mischley, L. K., Shankland, E. G., Liu, S. Z., Bhayana, S., Fox, D. J., & Marcinek, D. J. (2023) · Nutrients · doi:10.3390/nu15040943 · Cited by 41 · see citing works

Effect of nicotinamide riboside on airway inflammation in COPD: a randomized, placebo-controlled trial

Norheim, K. L., Ezra, M. B., Heckenbach, I., Andreasson, L. M., Eriksen, L. L., Dyhre‐Petersen, N., Damgaard, M. V., Berglind, M., Pricolo, L., Sampson, D. L., et al. (2024) · Nature Aging · doi:10.1038/s43587-024-00758-1 · Cited by 45 · see citing works

Nicotinamide Riboside, a Promising Vitamin B3 Derivative for Healthy Aging and Longevity: Current Research and Perspectives

Biţă, A., Scorei, I. R., Ciocîlteu, M. V., Nicolaescu, O. E., Pîrvu, A. S., Bejenaru, L. E., Rău, G., Bejenaru, C., Radu, A., Neamţu, J., et al. (2023) · Molecules · doi:10.3390/molecules28166078 · Cited by 41 · see citing works

NAD + Precursors in Human Health and Disease: Current Status and Future Prospects

Yaku, K., & Nakagawa, T. (2023) · Antioxidants and Redox Signaling · doi:10.1089/ars.2023.0354 · Cited by 31 · see citing works

Channeling Nicotinamide Phosphoribosyltransferase (NAMPT) to Address Life and Death

Reddy, V. G., Krider, I. S., Alves, E. T. M., Courey, J. M., Laham, M. S., & Thatcher, G. R. J. (2024) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.3c02112 · Cited by 27 · see citing works

NAD depletion in skeletal muscle does not compromise muscle function or accelerate aging

Chubanava, S., Karavaeva, I. E., Ehrlich, A. M., Justicia, R. M., Basse, A. L., Kulik, I., Dalbram, E., Ahwazi, D., Heaselgrave, S. R., Trôst, K., et al. (2025) · Cell Metabolism · doi:10.1016/j.cmet.2025.04.002 · Cited by 28 · see citing works

NAD+: An old but promising therapeutic agent for skeletal muscle ageing

Xu, Y., & Xiao, W. (2023) · Ageing Research Reviews · doi:10.1016/j.arr.2023.102106 · Cited by 19 · see citing works

Effects of NAD+ supplementation with oral nicotinamide riboside on vascular health and cognitive function in older adults with peripheral artery disease: Results from a pilot 4-week open-label clinical trial

Szarvas, Z., Reyff, Z., Péterfi, A., Pinto, C. B., Owens, C. D., Kaposzta, Z., Mukli, P., Pinaffi‐Langley, A. C. D. C., Adams, C., Muranyi, M., et al. (2025) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/j.jpet.2025.103607 · Cited by 18 · see citing works

NAD + precursor nutritional supplements sensitize the brain to future ischemic events

Qu, W., Ralto, K. M., Qin, T., Cheng, Y., Zong, W., Luo, X., Pérez‐Pinzón, M. A., Parikh, S. M., & Ayata, C. (2023) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x231156500 · Cited by 16 · see citing works

Targeting Intramyocellular Lipids to Improve Aging Muscle Function

Russ, D. W., Manickam, R., & Tipparaju, S. M. (2025) · Lipids in Health and Disease · doi:10.1186/s12944-025-02622-6 · Cited by 15 · see citing works

NAD⁺ supplementation for anti-aging and wellness: A PRISMA-guided systematic review of preclinical and clinical evidence

Gallagher, C., & Emmanuel, O. O. (2026) · Ageing Research Reviews · doi:10.1016/j.arr.2026.103057 · Cited by 14 · see citing works

Regular exercise effectively protects against the aging-associated decline in skeletal muscle NAD content

Chubanava, S., & Treebak, J. T. (2023) · Experimental Gerontology · doi:10.1016/j.exger.2023.112109 · Cited by 13 · see citing works

Lactate: A Theranostic Biomarker for Metabolic Psychiatry?

Caddye, E., Pineau, J., Reyniers, J., Ronen, I., & Colasanti, A. (2023) · Antioxidants · doi:10.3390/antiox12091656 · Cited by 11 · see citing works

The pterostilbene-dihydropyrazole derivative Ptd-1 ameliorates vascular calcification by regulating inflammation

Wei, X., Shen, Z., Zhu, M., Fang, M., Wang, S., Zhang, T., Zhang, B., Yang, X., Lv, Z.-L., Duan, Y., et al. (2023) · International Immunopharmacology · doi:10.1016/j.intimp.2023.111198 · Cited by 8 · see citing works

Program with last minute abstracts of the Padua Days on Muscle and Mobility Medicine, 27 February – 2 March, 2024 (2024Pdm3)

Zampieri, S., Bersch, I., Smeriglio, P., Barbieri, E., Boncompagni, S., Maccarone, M. C., & Carraro, U. (2024) · European Journal of Translational Myology · doi:10.4081/ejtm.2024.12346 · Cited by 8 · see citing works

Redox therapy for neuropsychiatric disorders: Molecular mechanisms and biomarker development

Cuklanz, K., Stein, A., Chouinard, V., Öngür, D., & Du, F. (2026) · Science Advances · doi:10.1126/sciadv.aea9014 · Cited by 5 · see citing works

Pterostilbene-mediated microbiota shifts: Implications and opportunities

Koh, Y., & Pan, M. (2025) · Journal of Traditional and Complementary Medicine · doi:10.1016/j.jtcme.2025.11.002 · Cited by 3 · see citing works

Five Padua days on muscle and mobility medicine (2024Pdm3) 27 February - 2 March, 2024 at Hotel Petrarca, Thermae of Euganean Hills, Padua, and San Luca Hall, Prato della Valle, Padua, Italy

Zampieri, S., Bersch, I., Smeriglio, P., Barbieri, E., Ganassi, M., Leeuwenburg, C., Rosati, R., Gargiulo, P., Pond, A. L., Sweeney, H. L., et al. (2023) · European Journal of Translational Myology · doi:10.4081/ejtm.2023.12161 · Cited by 3 · see citing works

Nicotinamide and Pyridoxine supplementation stimulates muscle stem cells in a randomized clinical trial on muscle repairPreprint

Højfeldt, G. W., Michaud, J., Damgaard, A., Karlog, K., Migliavacca, E., Karaz, S., Pazirandeh-Micol, E., Johansen, O. E., Karagounis, L. G., Helge, B. W., et al. (2025) · medRxiv · doi:10.1101/2025.03.24.25323226 · Cited by 3 · see citing works

Clinical evidence for the use of NAD+ precursors to slow aging

Khatri, S., Abdellatif, M., & Sedej, S. (2025) · Geromedicine · doi:10.70401/geromedicine.2025.0008 · Cited by 2 · see citing works

Nicotinamide and Pyridoxine Supplementation Enhances Muscle Stem Cell Activity and Muscle Regeneration in Humans: A Randomized Placebo‐Controlled Clinical Trial of High Force Eccentric Contraction Recovery in Healthy Young Men

Højfeldt, G. W., Michaud, J., Damgaard, A., Karlog, K., Migliavacca, E., Karaz, S., Pazirandeh-Micol, E., Johansen, O. E., Karagounis, L. G., Helge, B. W., et al. (2026) · Advanced Science · doi:10.1002/advs.202518471 · Cited by 5 · see citing works

Molecular Mechanisms and Nutritional Modulation in Sarcopenia: A Narrative Review

Chin, H. S., Liu, L., Liao, P.-J., Wee, A. L. R. M., Kwek, X.-Y., Teh, B. T., & Koh, F. H.-X. (2026) · Nutrients · doi:10.3390/nu18071161 · Cited by 2 · see citing works

Aging and cancer: current understandings and future perspectives

Li, Q., Chan, Y.-T., Wu, J., Jiang, Z., Lu, P., Xu, L., Feng, Z., Yuan, H., Feng, Y., & Wang, N. (2026) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-026-02756-8 · Cited by 2 · see citing works

Intranasal pterostilbene nanoparticles delivery alleviates neuroinflammation and brain injury after intracerebral hemorrhage

Duan, Z., Wang, Y., Zhang, Y., Liu, X., Wang, W., Li, H., Lu, Q., You, C., Cheng, Y., Wu, C., et al. (2025) · Chinese Chemical Letters · doi:10.1016/j.cclet.2025.111248 · Cited by 2 · see citing works

CD90 identifies distinct fractions of muscle stem cells with different modalities of activation and quiescence maintenancePreprint

Kheir, E., Libergoli, M., Metti, S., Jensen, J., Wang, J., Jessen, N., Florio, F., Murganti, F., Savino, S. D., Belicchi, M., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.10.25.619970 · Cited by 1 · see citing works

Virtual Nature, Metaverse, and NAD⁺: A Narrative Review for Health Planning and Healthy Ageing

Nakajima, T., & 幸生, 鯉. (2026) · Health Science Reports · doi:10.1002/hsr2.72389

Virtual reality nature, urban virtual reality, and exergaming in entertainment: implications for stress, healthy aging, and nicotinamide adenine dinucleotide+

Nakajima, T., & Koibuchi, Y. (2026) · Frontiers in Virtual Reality · doi:10.3389/frvir.2026.1781200

NAD⁺ biology and supplementation: From mechanisms to clinical perspectives

Pandolfi, S., Ghezzi, C., Bjørklund, G., Metalla, M., Paone, F. M., & Chirumbolo, S. (2026) · Molecular Biology Reports · doi:10.1007/s11033-026-12351-3

Strengthening muscle for healthy ageing: innovative treatments for sarcopenia

Ancel, S., Moal, E. L., Wang, Y. X., & Blau, H. M. (2026) · Nature Reviews Drug Discovery · doi:10.1038/s41573-026-01514-3

BindingDB Entry 50021721: Channeling Nicotinamide Phosphoribosyltransferase (NAMPT) to Address Life and Death.

BindingDB (2025) · UC San Diego · doi:10.7270/q25x2fk7

Nicotinamide and Pyridoxine Supplementation Enhances Muscle Stem Cell Activity and Muscle Regeneration in Humans: A Randomized Placebo‐Controlled Clinical Trial of High Force Eccentric Contraction Recovery in Healthy Young Men

Højfeldt, G. W., Michaud, J., Damgaard, A., Karlog, K., Migliavacca, E., Karaz, S., Pazirandeh-Micol, E., Johansen, O. E., Karagounis, L. G., Helge, B. W., et al. (2026) · Advanced Science · doi:10.1002/advs.202518471 · Cited by 5 · see citing works

Nicotinamide and Pyridoxine supplementation stimulates muscle stem cells in a randomized clinical trial on muscle repairPreprint

Højfeldt, G. W., Michaud, J., Damgaard, A., Karlog, K., Migliavacca, E., Karaz, S., Pazirandeh-Micol, E., Johansen, O. E., Karagounis, L. G., Helge, B. W., et al. (2025) · medRxiv · doi:10.1101/2025.03.24.25323226 · Cited by 3 · see citing works

Nicotinamide and pyridoxine stimulate muscle stem cell expansion and enhance regenerative capacity during aging

Ancel, S., Michaud, J., Migliavacca, E., Jomard, C., Fessard, A., Garcia, P., Karaz, S., Raja, S., Jacot, G. E., Desgeorges, T., et al. (2024) · Journal of Clinical Investigation · doi:10.1172/jci163648 · Cited by 25 · see citing works

Small molecule nicotinamide N-methyltransferase inhibitor activates senescent muscle stem cells and improves regenerative capacity of aged skeletal muscle

Neelakantan, H., Brightwell, C. R., Graber, T. G., Maroto, R., Wang, H.-Y. L., McHardy, S. F., Papaconstantinou, J., Fry, C. S., & Watowich, S. J. (2019) · Biochemical Pharmacology · doi:10.1016/j.bcp.2019.02.008 · Cited by 88 · see citing works

Nicotinamide and Pyridoxine Supplementation Enhances Muscle Stem Cell Activity and Muscle Regeneration in Humans: A Randomized Placebo‐Controlled Clinical Trial of High Force Eccentric Contraction Recovery in Healthy Young Men (Adv. Sci. 28/2026)

Højfeldt, G. W., Michaud, J., Damgaard, A., Karlog, K., Migliavacca, E., Karaz, S., Pazirandeh-Micol, E., Johansen, O. E., Karagounis, L. G., Helge, B. W., et al. (2026) · Advanced Science · doi:10.1002/advs.75392