Henson, Peter M.

Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF.

Fadok, V. A., Bratton, D. L., Konowal, A., Freed, P. W., Westcott, J. Y., & Henson, P. M. (1998) · Journal of Clinical Investigation

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Cell-Surface Calreticulin Initiates Clearance of Viable or Apoptotic Cells through trans-Activation of LRP on the Phagocyte

Gardai, S. J., McPhillips, K. A., Frasch, S. C., Janssen, W. J., Starefeldt, A., Murphy-Ullrich, J. E., Bratton, D. L., Oldenborg, P.-A., Michalak, M., & Henson, P. M. (2005) · Cell

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Monocyte differentiation and antigen-presenting functions

Jakubzick, C. V., Randolph, G. J., & Henson, P. M. (2017) · Nature Reviews Immunology

Immune cells in cancerImmunotherapy and Immune Responses

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Muc5b is required for airway defence

Roy, M. G., Livraghi-Butrico, A., Fletcher, A. A., McElwee, M. M., Evans, S. E., Boerner, R. M., Alexander, S. N., Bellinghausen, L. K., Song, A. S., Petrova, Y. M., et al. (2014) · Nature

Glycosylation and Glycoproteins ResearchAsthma and respiratory diseases

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Clearance of apoptotic cells by phagocytes

Erwig, L.-P., & Henson, P. M. (2008) · Cell Death & Differentiation

Phagocytosis and Immune RegulationCell death mechanisms and regulation

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The Immunologic Release of Constituents from Neutrophil Leukocytes

Henson, P. M. (1971) · The Journal of Immunology

Neutrophil, Myeloperoxidase and Oxidative MechanismsInflammation biomarkers and pathways

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Immunological Consequences of Apoptotic Cell Phagocytosis

Erwig, L.-P., & Henson, P. M. (2007) · The American Journal of Pathology

Phagocytosis and Immune RegulationImmune Response and Inflammation

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Hemophagocytosis causes a consumptive anemia of inflammation

Zoller, E. E., Lykens, J. E., Terrell, C. E., Aliberti, J., Filipovich, A. H., Henson, P. M., & Jordan, M. B. (2011) · Journal of Experimental Medicine

Autoimmune and Inflammatory Disorders ResearchIron Metabolism and Disorders

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The Immunologic Release of Constituents from Neutrophil Leukocytes

Henson, P. M. (1971) · The Journal of Immunology

Neutrophil, Myeloperoxidase and Oxidative MechanismsCellular transport and secretion

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Tumor Necrosis Factor-α Accelerates the Resolution of Established Pulmonary Fibrosis in Mice by Targeting Profibrotic Lung Macrophages

Redente, E. F., Keith, R. C., Janssen, W., Henson, P. M., Ortiz, L. A., Downey, G. P., Bratton, D. L., & Riches, D. W. H. (2014) · American Journal of Respiratory Cell and Molecular Biology

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisOccupational and environmental lung diseases

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Deletion of c-FLIP from CD11bhi Macrophages Prevents Development of Bleomycin-induced Lung Fibrosis

McCubbrey, A. L., Barthel, L., Mohning, M. P., Redente, E. F., Mould, K. J., Thomas, S. M., Leach, S. M., Danhorn, T., Gibbings, S. L., Jakubzick, C. V., et al. (2018) · American Journal of Respiratory Cell and Molecular Biology

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisTransplantation: Methods and Outcomes

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Regulation of macrophage cytokine production by phagocytosis of apoptotic and post-apoptotic cells

Fadok, V. A., McDonald, P. P., Bratton, D. L., & Henson, P. M. (1998) · Biochemical Society Transactions

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Hemophagocytic macrophages harbor Salmonella enterica during persistent infection

Nix, R. N., Altschuler, S. E., Henson, P. M., & Detweiler, C. S. (2007) · PLoS Pathogens

Salmonella and Campylobacter epidemiologyBacterial Genetics and Biotechnology

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Impaired Phagocytosis of Apoptotic Cells by Macrophages in Chronic Granulomatous Disease Is Reversed by IFN-γ in a Nitric Oxide-Dependent Manner

Fernandez-Boyanapalli, R., McPhillips, K. A., Frasch, S. C., Janssen, W. J., Dinauer, M. C., Riches, D. W. H., Henson, P. M., Byrne, A., & Bratton, D. L. (2010) · The Journal of Immunology

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PPARγ activation normalizes resolution of acute sterile inflammation in murine chronic granulomatous disease

Fernandez-Boyanapalli, R., Frasch, S. C., Riches, D. W. H., Vandivier, R. W., Henson, P. M., & Bratton, D. L. (2010) · Blood

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TNFα inhibits apoptotic cell clearance in the lung, exacerbating acute inflammation

Borges, V. M., Vandivier, R. W., McPhillips, K. A., Kench, J. A., Morimoto, K., Groshong, S. D., Richens, T. R., Graham, B. B., Muldrow, A. M., Heule, L. V., et al. (2009) · American Journal of Physiology-Lung Cellular and Molecular Physiology

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